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{{Infobox_Disease
__NOTOC__
| Name          = {{PAGENAME}}
{{Giardiasis}}
| Image          = Giardia lamblia SEM 8698 lores.jpg
{{About1|Giardia lamblia}}
| Caption        = ''Giardia'' cell, SEM
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
| DiseasesDB    = 5213
| ICD10          =  {{ICD10|A|07|1|a|00}}
| ICD9          = {{ICD9|007.1}}
| ICDO          =
| OMIM          =
| MedlinePlus    = 000288
| eMedicineSubj  = emerg
| eMedicineTopic = 215
| MeshID        = D005873
}}
{{SI}}
{{Editor Help}}


==Overview==
{{CMG}}; '''Associate Editor-In-Chief:''' {{YD}}; {{SSK}}; {{CZ}}
'''Giardiasis''' (also known as '''beaver fever''') is a disease caused by the [[flagellate|flagellate protozoan]] ''[[Giardia lamblia]]'' (also sometimes called ''Giardia intestinalis'' and ''Giardia duodenalis'') <ref>Huang, White. An Updated Review on Cryptosporidium and Giardia ''Gastroenterol Clin N Am 35'' (2006) 291–314</ref>. The giardia organism inhabits the digestive tract of a wide variety of domestic and wild animal species, including humans. It is a common cause of [[gastroenteritis]] in humans, infecting approximately 200 million people worldwide.


==Transmission==
{{SK}} Beaver fever, Giardiosis; Giardia enteritis; Lambliasis; Giardia infection; Giardia lamblia infection; Giardia intestinalis infection
Giardiasis is passed via the [[fecal-oral route]]. Primary routes are personal contact and contaminated water and food. People who spend time in institutional or day-care environments are more susceptible, as are travelers and those who consume improperly treated water. It is a particular danger to people hiking or backpacking in wilderness areas worldwide. Giardia is suspected to be [[zoonotic]]—communicable between animals and humans.  Major reservoir hosts would include beavers, dogs, cats, horses, and cattle.


==Symptoms==
==[[Giardiasis overview|Overview]]==
Symptoms include loss of appetite, lethargy, fever, explosive diarrhea, loose or watery stool, stomach cramps, upset stomach, projectile vomiting (uncommon), bloating, and flatulence. Symptoms typically begin 1–2 weeks after infection and may wane and reappear cyclically.  Symptoms are caused largely by the thick coating of ''Giardia'' organisms coating the inside of the [[small intestine]] and blocking nutrient absorption.  Most people are asymptomatic; only about a third of infected people exhibit symptoms.


==Treatment==
==[[Giardiasis historical perspective|Historical Perspective]]==
Drugs used to treat adults include [[metronidazole]], [[albendazole]] and [[quinacrine]]. [[Furazolidone]] and [[nitazoxanide]] may be used in children. Treatment is not always necessary, as the body can defeat the infection by itself.
 
==[[Giardiasis classification|Classification]]==
 
==[[Giardiasis pathophysiology|Pathophysiology]]==
 
==[[Giardiasis causes|Causes]]==
 
==[[Giardiasis differential diagnosis|Differentiating Giardiasis from other Diseases]]==
 
==[[Giardiasis epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Giardiasis risk factors|Risk Factors]]==


The drug [[tinidazole]] can treat giardiasis in a single treatment of 2000 mg, instead of the longer treatment of the other medications listed. The shorter duration of treatment may also cause less patient distress. Tinidazole is now approved by the FDA<ref name="FDA">[http://www.fda.gov/Cder/consumerinfo/druginfo/tindamax.htm FDA info on Tindamax].</ref> and available to U.S. patients.
==[[Giardiasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


==Testing==
==Diagnosis==


While most sources suggest that commonly used tests for giardia are unreliable, a new immunologic test referred to as ELISA, for [[enzyme-linked immunosorbent assay]] are now available.  These tests are capable of a 90 percent detection rate or more. <ref>[http://www.yosemite.org/naturenotes/Giardia.htm#_ednref7 Giardia Lamblia and Giardiasis by Robert L. Rockwell, PhD ]</ref>
[[Giardiasis history and symptoms|History and Symptoms]] | [[Giardiasis physical examination|Physical Examination]] | [[Giardiasis laboratory findings|Laboratory Findings]] | [[Giardiasis other diagnostic studies|Other Diagnostic Studies]]


==References==
==Treatment==
{{Reflist|2}}


==External links==
[[Giardiasis medical therapy|Medical Therapy]] | [[Giardiasis prevention|Prevention]] | [[Giardiasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Giardiasis future or investigational therapies|Future or Investigational Therapies]]
*[http://www.cdc.gov/ncidod/dpd/parasites/giardiasis/factsht_giardia.htm Giardiasis Fact Sheet]
 
*[http://www.emedicinehealth.com/articles/17334-1.asp eMedicine Health Giardiasis]
==Case Studies==
[[Giardiasis case study one|Case #1]]
 
==External Links==
*[http://www.cdc.gov/parasites/giardia/ Giardiasis Fact Sheet]


{{Protozoal diseases}}
{{Protozoal diseases}}
 
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Parasitic diseases]]
[[Category:Parasitic diseases]]
[[Category:Water-borne diseases]]
[[Category:Water-borne diseases]]
[[Category:Infectious disease]]


{{SIB}}


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Latest revision as of 17:49, 18 September 2017

Giardiasis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Giardiasis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Risk calculators and risk factors for Giardiasis

This page is about clinical aspects of the disease.  For microbiologic aspects of the causative organism(s), see Giardia lamblia.

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.; Cafer Zorkun, M.D., Ph.D. [2]

Synonyms and keywords: Beaver fever, Giardiosis; Giardia enteritis; Lambliasis; Giardia infection; Giardia lamblia infection; Giardia intestinalis infection

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Giardiasis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

External Links

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Template:WikiDoc Sources