Gestational trophoblastic neoplasia staging: Difference between revisions
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==Overview== | ==Overview== | ||
According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) [[cancer staging]] system, there are 4 stages of choriocarcinoma. | According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) [[cancer staging]] system, there are 4 stages of choriocarcinoma.<ref name= eee>Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015</ref> | ||
==Staging== | ==Staging== | ||
The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system is as follows: | The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system is as follows:<ref name= eee>Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015</ref> | ||
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Revision as of 19:00, 15 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) cancer staging system, there are 4 stages of choriocarcinoma.[1]
Staging
The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system is as follows:[1]
| Stage | FIGO Anatomical Staging |
|---|---|
|
I |
Disease confined to the uterus |
|
II |
GTN extends outside of the uterus, but is limited to the genital structures (adnexa, vagina, broad ligament) |
|
III |
GTN extends to the lungs, with or without known genital tract involvement |
|
IV |
All other metastatic sites |
The modified World Health Organization [WHO] prognostic scoring system is as follows:
| Modified WHO Prognostic Scoring System as Adapted by FIGO | ||||
| Scores | 0 | 1 | 2 | 4 |
| Age | <40 | ≥40 | – | – |
| Antecedent pregnancy | mole | abortion | term | – |
| Interval months from index pregnancy | <4 | 4–6 | 7–12 | >12 |
| Pretreatment serum hCG (iu/1) | <103 | 103–104 | 104–105 | >105 |
| Largest tumor size (including uterus) | <3 | 3–4 cm | ≥5 cm | – |
| Site of metastases | lung | spleen, kidney | gastrointestinal | liver, brain |
| Number of metastases | – | 1–4 | 5–8 | >8 |
| Previous failed chemotherapy | – | – | single drug | ≥2 drugs |
References
- ↑ 1.0 1.1 Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015