Germ cell tumor screening: Difference between revisions

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* According to the '''KIT'' [[Mutation|Mutations]] Are Common in [[Testicular]] Seminomas' study, [[Screening (medicine)|screening]] for seminoma by using the highly sensitive combination of denaturing [[High performance liquid chromatography|high performance liquid chromatography (HPLC)]] and direct [[sequencing]] observed:<ref name="pmid14695343">{{cite journal |vauthors=Kemmer K, Corless CL, Fletcher JA, McGreevey L, Haley A, Griffith D, Cummings OW, Wait C, Town A, Heinrich MC |title=KIT mutations are common in testicular seminomas |journal=Am. J. Pathol. |volume=164 |issue=1 |pages=305–13 |date=January 2004 |pmid=14695343 |pmc=1602213 |doi=10.1016/S0002-9440(10)63120-3 |url=}}</ref>
* According to the '''KIT'' [[Mutation|Mutations]] Are Common in [[Testicular]] Seminomas' study, [[Screening (medicine)|screening]] for seminoma by using the highly sensitive combination of denaturing [[High performance liquid chromatography|high performance liquid chromatography (HPLC)]] and direct [[sequencing]] observed:<ref name="pmid14695343">{{cite journal |vauthors=Kemmer K, Corless CL, Fletcher JA, McGreevey L, Haley A, Griffith D, Cummings OW, Wait C, Town A, Heinrich MC |title=KIT mutations are common in testicular seminomas |journal=Am. J. Pathol. |volume=164 |issue=1 |pages=305–13 |date=January 2004 |pmid=14695343 |pmc=1602213 |doi=10.1016/S0002-9440(10)63120-3 |url=}}</ref>
**[[Mutation|Mutations]] of KIT [[exon]] 17
**[[Mutation|Mutations]] of D816H
**[[Mutation|Mutations]] of Y823D
'''Germinoma:'''
*According to the United States Preventive Services Task Force, [[Screening (medicine)|screening]] for intracranial germ cell tumor (germinoma) is not recommended among the general population.<ref name="screening">http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=germinoma Accessed on January 26, 2016.</ref>


*<nowiki>* </nowiki>[[Mutation|Mutations]] of KIT [[exon]] 17
*<nowiki>* </nowiki>[[Mutation|Mutations]] of D816H
*<nowiki>* </nowiki>[[Mutation|Mutations]] of Y823D





Latest revision as of 19:59, 21 August 2019

Ovarian germ cell tumor:

Testicular germ cell tumor:

Germinoma:

  • According to the United States Preventive Services Task Force, screening for intracranial germ cell tumor (germinoma) is not recommended among the general population.[3]




References

  1. Grossman, David C.; Curry, Susan J.; Owens, Douglas K.; Barry, Michael J.; Davidson, Karina W.; Doubeni, Chyke A.; Epling, John W.; Kemper, Alex R.; Krist, Alex H.; Kurth, Ann E.; Landefeld, C. Seth; Mangione, Carol M.; Phipps, Maureen G.; Silverstein, Michael; Simon, Melissa A.; Tseng, Chien-Wen (2018). "Screening for Ovarian Cancer". JAMA. 319 (6): 588. doi:10.1001/jama.2017.21926. ISSN 0098-7484.
  2. Kemmer K, Corless CL, Fletcher JA, McGreevey L, Haley A, Griffith D, Cummings OW, Wait C, Town A, Heinrich MC (January 2004). "KIT mutations are common in testicular seminomas". Am. J. Pathol. 164 (1): 305–13. doi:10.1016/S0002-9440(10)63120-3. PMC 1602213. PMID 14695343.
  3. http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=germinoma Accessed on January 26, 2016.