Gastroparesis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

There are no diagnostic laboratory findings associated with gastroparesis. However, some laboratory findings consistent with the diagnosis of gastroparesis and its complications include elevated blood urea nitrogen (BUN), creatinine, erythrocyte sedimentation rate (ESR), or C-reactive protein (CRP). Elevated glucose or glycated hemoglobin levels (HbA1c) might be seen in patients with diabetic gastroparesis.

There are no diagnostic laboratory findings associated with gastroparesis.
Laboratory findings consistent with the diagnosis of gastroparesis and its complications include:^[1]^[2]^[3]
- Elevated BUN in severe dehydration (normal BUN <20 mg/dL)
- Elevated creatinine in severe dehydration (normal creatinine <1.1 mg/dL for female, <1.2 mg/dL for male)
- Elevated c-reactive protein (normal CRP <0.8 mg/dL)
- Elevated erythrocyte sedimentation rate (normal ESR <20 mm/h)
- Hypoalbuminemia (normal albumin >3.5 g/dL)
Patients with gastroparesis might have abnormal tests depends on underlying cause:^[1]
- Elevated HbA1C (in diabetic gastroparesis)
- Elevated glucose (in diabetic gastroparesis)
- Elevated TSH in gastroparesis due to hypothyroidism (normal 0.4-5 mU/L)^[4]

↑ ^1.0 ^1.1 Parkman, Henry P.; Yates, Katherine P.; Hasler, William L.; Nguyan, Linda; Pasricha, Pankaj J.; Snape, William J.; Farrugia, Gianrico; Calles, Jorge; Koch, Kenneth L.; Abell, Thomas L.; McCallum, Richard W.; Petito, Dorothy; Parrish, Carol Rees; Duffy, Frank; Lee, Linda; Unalp–Arida, Aynur; Tonascia, James; Hamilton, Frank (2011). "Dietary Intake and Nutritional Deficiencies in Patients With Diabetic or Idiopathic Gastroparesis". Gastroenterology. 141 (2): 486–498.e7. doi:10.1053/j.gastro.2011.04.045. ISSN 0016-5085.
↑ Pasricha, Pankaj J.; Yates, Katherine P.; Nguyen, Linda; Clarke, John; Abell, Thomas L.; Farrugia, Gianrico; Hasler, William L.; Koch, Kenneth L.; Snape, William J.; McCallum, Richard W.; Sarosiek, Irene; Tonascia, James; Miriel, Laura A.; Lee, Linda; Hamilton, Frank; Parkman, Henry P. (2015). "Outcomes and Factors Associated With Reduced Symptoms in Patients With Gastroparesis". Gastroenterology. 149 (7): 1762–1774.e4. doi:10.1053/j.gastro.2015.08.008. ISSN 0016-5085.
↑ Stein, Benjamin; Everhart, Kelly K.; Lacy, Brian E. (2015). "Gastroparesis". Journal of Clinical Gastroenterology. 49 (7): 550–558. doi:10.1097/MCG.0000000000000320. ISSN 0192-0790.
↑ Caldwell G, Kellett HA, Gow SM, Beckett GJ, Sweeting VM, Seth J; et al. (1985). "A new strategy for thyroid function testing". Lancet. 1 (8438): 1117–9. PMID 2860333.