Gallstone disease history and symptoms

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Gallstone disease Microchapters


Patient Information


Historical Perspective




Differentiating Gallstone disease from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


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History and Symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]


Gallstone disease can manifest in a number of ways. Most patients have a history of obesity, multiple pregnancies, use of oral contraceptive pills, age of 40 years old and over, female and of Caucasian or Native American race. Some patients may be in a physical state that favors the development of gallstones but don't develop them, some patients may have gallstones, but are asymptomatic. These gallstones are detected incidentally. Some may have gallstones and experience biliary colic, nausea, vomiting and diarrhea, whilst others will have complications due to gallstones, such as acute cholecystitis and acute pancreatitis.

History and Symptoms


  • Obtaining history is an important aspect of making a diagnosis of gallstone disease.[1][2]

Common Symptoms

Less Common Symptoms

Less common symptoms include:[5]


  1. 1.0 1.1 Diehl AK, Sugarek NJ, Todd KH (1990). "Clinical evaluation for gallstone disease: usefulness of symptoms and signs in diagnosis". Am. J. Med. 89 (1): 29–33. PMID 2368790.
  2. Johnson CD (2001). "ABC of the upper gastrointestinal tract. Upper abdominal pain: Gall bladder". BMJ. 323 (7322): 1170–3. PMC 1121646. PMID 11711412.
  3. "Gallstones". Medline Plus. Retrieved 2007-08-25.
  4. LUND J (1960). "Surgical indications in cholelithiasis: prophylactic choleithiasis: prophylactic cholecystectomy elucidated on the basis of long-term follow up on 526 nonoperated cases". Ann. Surg. 151: 153–62. PMC 1613279. PMID 13848582.
  5. Berger MY, Olde Hartman TC, Bohnen AM (2003). "Abdominal symptoms: do they disappear after cholecystectomy?". Surg Endosc. 17 (11): 1723–8. doi:10.1007/s00464-002-9154-6. PMID 12802649.

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