Gallbladder cancer risk factors

Jump to navigation Jump to search

Gallbladder cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Differentiating Gallbladder cancer from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

CT

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Palliative Treatment

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Gallbladder cancer risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Gallbladder cancer risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Gallbladder cancer risk factors

CDC on Gallbladder cancer risk factors

Gallbladder cancer risk factors in the news

Blogs on Gallbladder cancer risk factors

Directions to Hospitals Treating Gallbladder cancer

Risk calculators and risk factors for Gallbladder cancer risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Common risk factors in the development of gallbladder cancer are obesity, chronic cholecystitis, chronic cholelithiasis, chronic typhoid infection, alcohol and genetic mutations.

Risk factors

  • Obesity increases the risk for gallbladder cancer
  • Chronic cholecystitis and cholelithiasis
  • Chronic typhoid infection of gallbladder. Chronic salmonella typhi carriers have 3 to 200 times higher risk of gallbladder cancer than non-carriers and 1–6% lifetime risk of development of cancer[1]
  • Various single nucleotide polymorphisms (SNPs) have been shown to be associated with gallbladder cancer. However, existing genetic studies in gallbladder cancer susceptibility have so far been insufficient to confirm any association[2]
  • Alcohol: Alcohol drinking is a risk factor of gallbladder cancer[3] [4]

References

  1. Ferreccio, Catterina (2012). "Salmonella typhi and Gallbladder Cancer": 117–137. doi:10.1007/978-94-007-2585-0_5.
  2. Srivastava K, Srivastava A, Sharma KL, Mittal B (2011). "Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis". Mutat Res. 728 (1–2): 67–79. doi:10.1016/j.mrrev.2011.06.002. PMC 3162044. PMID 21708280.
  3. Ji, J (2005 Sep). "Variation in the risk for liver and gallbladder cancers in socioeconomic and occupational groups in Sweden with etiological implications". Int Arch Occup Environ Health. 78 (8): 641–9. PMID 16001211. Retrieved 28 May 2007. Unknown parameter |coauthors= ignored (help); Check date values in: |date= (help)
  4. Ji J, Couto E, Hemminki K. Incidence differences for gallbladder cancer between occupational groups suggest an etiological role for alcohol Int J Cancer 2005 Sep 1;116(3):492-3.


Template:WikiDoc Sources