GIMAP5: Difference between revisions

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{{Infobox_gene}}
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'''GTPase IMAP family member 5''' is an [[enzyme]] that in humans is encoded by the ''GIMAP5'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GIMAP5 GTPase, IMAP family member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55340| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = GTPase, IMAP family member 5
| HGNCid = 18005
| Symbol = GIMAP5
| AltSymbols =; FLJ11296; HIMAP3; IAN4; IAN4L1; IAN5; IMAP3; hIAN5
| OMIM = 608086
| ECnumber = 
| Homologene = 41257
| MGIid = 2442232
| GeneAtlas_image1 = PBB_GE_GIMAP5_218805_at_tn.png
| GeneAtlas_image2 = PBB_GE_GIMAP5_64064_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0019867 |text = outer membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55340
    | Hs_Ensembl = ENSG00000196329
    | Hs_RefseqProtein = NP_060854
    | Hs_RefseqmRNA = NM_018384
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 150065384
    | Hs_GenLoc_end = 150071669
    | Hs_Uniprot = Q96F15
    | Mm_EntrezGene = 317757
    | Mm_Ensembl = ENSMUSG00000043505
    | Mm_RefseqmRNA = XM_974104
    | Mm_RefseqProtein = XP_979198
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 48675783
    | Mm_GenLoc_end = 48683786
    | Mm_Uniprot = Q8BWF2
  }}
}}
'''GTPase, IMAP family member 5''', also known as '''GIMAP5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GIMAP5 GTPase, IMAP family member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55340| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.<ref name="entrez">{{cite web | title = Entrez Gene: GIMAP5 GTPase, IMAP family member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55340| accessdate = }}</ref>
| summary_text = This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.<ref name="entrez">{{cite web | title = Entrez Gene: GIMAP5 GTPase, IMAP family member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55340| accessdate = }}</ref>
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Dahéron L, Zenz T, Siracusa LD, ''et al.'' |title=Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity. |journal=Nucleic Acids Res. |volume=29 |issue= 6 |pages= 1308-16 |year= 2001 |pmid= 11238997 |doi=  }}
*{{cite journal  |vauthors=Dahéron L, Zenz T, Siracusa LD |title=Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity. |journal=Nucleic Acids Res. |volume=29 |issue= 6 |pages= 1308–16 |year= 2001 |pmid= 11238997 |doi=10.1093/nar/29.6.1308  | pmc=29751 |display-authors=etal}}
*{{cite journal  | author=Stamm O, Krücken J, Schmitt-Wrede HP, ''et al.'' |title=Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36. |journal=Gene |volume=282 |issue= 1-2 |pages= 159-67 |year= 2002 |pmid= 11814688 |doi=  }}
*{{cite journal  |vauthors=Stamm O, Krücken J, Schmitt-Wrede HP |title=Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36. |journal=Gene |volume=282 |issue= 1–2 |pages= 159–67 |year= 2002 |pmid= 11814688 |doi=10.1016/S0378-1119(01)00837-X |display-authors=etal}}
*{{cite journal  | author=Cambot M, Aresta S, Kahn-Perlès B, ''et al.'' |title=Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells. |journal=Blood |volume=99 |issue= 9 |pages= 3293-301 |year= 2002 |pmid= 11964296 |doi=  }}
*{{cite journal  |vauthors=Cambot M, Aresta S, Kahn-Perlès B |title=Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells |journal=Blood |volume=99 |issue= 9 |pages= 3293–301 |year= 2002 |pmid= 11964296 |doi=10.1182/blood.V99.9.3293 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  |vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 | pmc=2882961 |doi= 10.1126/science.1083423 |display-authors=etal}}
*{{cite journal  | author=Sandal T, Aumo L, Hedin L, ''et al.'' |title=Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis. |journal=Mol. Biol. Cell |volume=14 |issue= 8 |pages= 3292-304 |year= 2004 |pmid= 12925764 |doi= 10.1091/mbc.E02-10-0700 }}
*{{cite journal  |vauthors=Sandal T, Aumo L, Hedin L |title=Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis |journal=Mol. Biol. Cell |volume=14 |issue= 8 |pages= 3292–304 |year= 2004 |pmid= 12925764 |doi= 10.1091/mbc.E02-10-0700 | pmc=181568 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Zenz T, Roessner A, Thomas A, ''et al.'' |title=hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies. |journal=Genes Immun. |volume=5 |issue= 2 |pages= 109-16 |year= 2004 |pmid= 14724691 |doi= 10.1038/sj.gene.6364044 }}
*{{cite journal  |vauthors=Zenz T, Roessner A, Thomas A |title=hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies |journal=Genes Immun. |volume=5 |issue= 2 |pages= 109–16 |year= 2004 |pmid= 14724691 |doi= 10.1038/sj.gene.6364044 |display-authors=etal}}
*{{cite journal  | author=Krücken J, Schroetel RM, Müller IU, ''et al.'' |title=Comparative analysis of the human gimap gene cluster encoding a novel GTPase family. |journal=Gene |volume=341 |issue=  |pages= 291-304 |year= 2005 |pmid= 15474311 |doi= 10.1016/j.gene.2004.07.005 }}
*{{cite journal  |vauthors=Krücken J, Schroetel RM, Müller IU |title=Comparative analysis of the human gimap gene cluster encoding a novel GTPase family |journal=Gene |volume=341 |issue=  |pages= 291–304 |year= 2005 |pmid= 15474311 |doi= 10.1016/j.gene.2004.07.005 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Hellquist A, Zucchelli M, Kivinen K, ''et al.'' |title=The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus. |journal=J. Med. Genet. |volume=44 |issue= 5 |pages= 314-21 |year= 2007 |pmid= 17220214 |doi= 10.1136/jmg.2006.046185 }}
*{{cite journal  |vauthors=Hellquist A, Zucchelli M, Kivinen K |title=The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus |journal=J. Med. Genet. |volume=44 |issue= 5 |pages= 314–21 |year= 2007 |pmid= 17220214 |doi= 10.1136/jmg.2006.046185 | pmc=2597989 |display-authors=etal}}
*{{cite journal  | author=Dalberg U, Markholst H, Hornum L |title=Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells. |journal=Int. Immunol. |volume=19 |issue= 4 |pages= 447-53 |year= 2007 |pmid= 17369194 |doi= 10.1093/intimm/dxm009 }}
*{{cite journal  |vauthors=Dalberg U, Markholst H, Hornum L |title=Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells |journal=Int. Immunol. |volume=19 |issue= 4 |pages= 447–53 |year= 2007 |pmid= 17369194 |doi= 10.1093/intimm/dxm009 }}
*{{cite journal  | author=Shin JH, Janer M, McNeney B, ''et al.'' |title=IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5. |journal=Genes Immun. |volume=8 |issue= 6 |pages= 503-12 |year= 2007 |pmid= 17641683 |doi= 10.1038/sj.gene.6364413 }}
*{{cite journal  |vauthors=Shin JH, Janer M, McNeney B |title=IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5 |journal=Genes Immun. |volume=8 |issue= 6 |pages= 503–12 |year= 2007 |pmid= 17641683 |doi= 10.1038/sj.gene.6364413 |display-authors=etal}}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 08:44, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

GTPase IMAP family member 5 is an enzyme that in humans is encoded by the GIMAP5 gene.[1]

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.[1]

References

  1. ↑ 1.0 1.1 "Entrez Gene: GIMAP5 GTPase, IMAP family member 5".

Further reading



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