GAS7

Growth arrest-specific 7
Identifiers
Symbols	GAS7 ; MLL/GAS7; KIAA0394; MGC1348
External IDs	Template:OMIM5 Template:MGI HomoloGene: 69015
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Growth arrest-specific 7, also known as GAS7, is a human gene.

Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described.

Further reading

• Kurtz A, Zimmer A (1995). "Interspecies fluorescence in situ hybridization further defines synteny homology between mouse chromosome 11 and human chromosome 17". Mamm. Genome. 6 (5): 379–80. PMID 7626897.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ishikawa K, Nagase T, Nakajima D; et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. PMID 9455477.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ju YT, Chang AC, She BR; et al. (1998). "gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation". Proc. Natl. Acad. Sci. U.S.A. 95 (19): 11423–8. PMID 9736752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Megonigal MD, Cheung NK, Rappaport EF; et al. (2000). "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2814–9. doi:10.1073/pnas.050397097. PMID 10706619.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• She BR, Liou GG, Lin-Chao S (2002). "Association of the growth-arrest-specific protein Gas7 with F-actin induces reorganization of microfilaments and promotes membrane outgrowth". Exp. Cell Res. 273 (1): 34–44. doi:10.1006/excr.2001.5435. PMID 11795944.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chao CC, Chang PY, Lu HH (2005). "Human Gas7 isoforms homologous to mouse transcripts differentially induce neurite outgrowth". J. Neurosci. Res. 81 (2): 153–62. doi:10.1002/jnr.20552. PMID 15948147.CS1 maint: Multiple names: authors list (link)