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{{Pneumonia}}
__NOTOC__
{{Fungal pneumonia}}
'''For the main page on pneumonia, click [[Pneumonia|here]]'''


'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information, click [[Fungal pneumonia (patient information)|here]]'''


'''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; [[Philip Marcus, M.D., M.P.H.]][mailto:pmarcus192@aol.com]
'''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:charlesmichaelgibson@gmail.com] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com]


==[[Pneumonia overview|Overview]]==
==[[Fungal pneumonia overview#Fungal pneumonia|Overview]]==


==[[Pneumonia historical perspective|Historical Perspective]]==  
==[[Fungal pneumonia historical perspective|Historical Perspective]]==
==[[Fungal pneumonia classification|Classification]]==


==[[Pneumonia pathophysiology|Pathophysiology]]==
==[[Fungal pneumonia pathophysiology|Pathophysiology]]==


==[[Pneumonia causes|Causes]]==
==[[Fungal pneumonia causes|Causes]]==
:'''Specific causes:''' [[bacterial pneumonia|Bacterial]] | [[fungal pneumonia|Fungal]] | [[parasitic pneumonia|Parasitic]] | [[viral pneumonia|Viral]]
:'''Classification scheme:''' [[Community-acquired pneumonia]] | [[Hospital-acquired pneumonia|Health-care associated pneumonia]]
:'''Other types:''' [[Severe acute respiratory syndrome]] | [[Bronchiolitis obliterans organizing pneumonia]] | [[Eosinophilic pneumonia]] | [[Chemical pneumonia]] | [[Aspiration pneumonia]]


==[[Pneumonia differential diagnosis|Differentiating Pneumonia from other Diseases]]==
==[[Fungal pneumonia differential diagnosis|Differentiating Fungal pneumonia from other Diseases]]==


==[[Pneumonia epidemiology and demographics|Epidemiology and Demographics]]==
==[[Fungal pneumonia epidemiology and demographics|Epidemiology and Demographics]]==


==[[Pneumonia risk factors|Risk factors]]==
==[[Fungal pneumonia risk factors|Risk factors]]==


==[[Pneumonia natural history, complications, and prognosis|Natural History, Complications and Prognosis]]==
==[[Fungal pneumonia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
'''Prognosis predictor scores:''' [[CURB-65]] | [[Pneumonia severity index]] | [[Pneumonia medical therapy#Criteria for severe community acquired pneumonia|Criteria for severe community acquired pneumonia]]


==Diagnosis==  
==Diagnosis==  


[[Pneumonia history and symptoms| History and Symptoms]] | [[Pneumonia physical examination | Physical Examination]] | [[Pneumonia laboratory studies |Laboratory Findings]] | [[Pneumonia chest x ray|Chest X Ray]] | [[Pneumonia CT|CT]]
[[Fungal pneumonia history and symptoms| History and Symptoms]] | [[Fungal pneumonia physical examination | Physical Examination]] | [[Fungal pneumonia laboratory findings |Laboratory Findings]] | [[Fungal pneumonia chest x ray|Chest X Ray]] | [[Fungal pneumonia CT|CT]] | [[Fungal pneumonia other imaging findings|Other Imaging Findings]] | [[Fungal pneumonia other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Fungal pneumonia medical therapy|Medical Therapy]] | [[Fungal pneumonia primary prevention|Primary Prevention]] | [[Fungal pneumonia secondary prevention|Prevention]] | [[Fungal pneumonia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Fungal pneumonia future or investigational therapies|Future or Investigational Therapies]]


[[Pneumonia medical therapy#Pneumonia site of care decision|Site of care decision]] | [[Pneumonia medical therapy|Medical Therapy]] | [[Pneumonia medical therapy#Other treatments consideration|Other treatments consideration]] | [[Pneumonia prevention|Prevention]] | [[Pneumonia medical therapy#Management of non-responding pneumonia|Management of non-responding pneumonia]]
==Case Studies==
[[Category:Diseaase]]
[[Fungal pneumonia case study one|Case #1]]
[[Category:Disease]]
[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Infectious disease]]
[[Category:Pneumonia|Pneumonia]]
[[Category:Emergency medicine]]
{{WH}}
{{WS}}
==Pathophysiology & Etiology==
Fungi typically enter the lung with inhalation of their spores, though they can reach the lung through the bloodstream if other parts of the body are infected. Also, fungal pneumonia can be caused by reactivation of a latent infection. Once inside the alveoli, fungi travel into the spaces between the cells and also between adjacent alveoli through connecting pores. This invasion triggers the immune system to respond by sending white blood cells responsible for attacking microorganisms (neutrophils) to the lungs. The neutrophils engulf and kill the offending organisms but also release cytokines which result in a general activation of the immune system. This results in the fever, chills, and fatigue common in bacterial and fungal pneumonia. The neutrophils and fluid leaked from surrounding blood vessels fill the alveoli and result in impaired oxygen transportation.
===Etiologic agent===
Specific instances of fungal infections that can manifest with pulmonary involvement include:
*[[Pneumocystis jirovecii pneumonia]]
*[[Histoplasmosis]], which has primary pulmonary lesions and hematogenous dissemination
*[[Coccidioidomycosis]], which begins with an often self-limited respiratory infection (also called "Valley fever" or "San Joaquin fever")
*[[Pulmonary blastomycosis]]
*[[Sporotrichosis]] - primarily a lymphocutaneous disease, but can involve the lungs as well
*[[Cryptococcosis]] - contracted through inhalation of soil contaminated with the yeast, it can manifest as a pulmonary infection and as a disseminated one
*[[Aspergillosis]], resulting in invasive pulmonary aspergillosis
*rarely, [[Candidiasis]] has pulmonary manifestations in immunocompromised patients.
==Risk Stratification and Prognosis==
Case mortality in fungal pneumonias can be as high as 70% in immunocompromised patients, though immunocompetent patients generally respond well to anti-fungal therapy.
==Treatment==
Fungal pneumonia can be treated with antifungal drugs and sometimes by surgical debridement.
==References==
{{reflist|2}}


[[Category:Diseaase]]
[[Category:Pneumonia]]
[[Category:Pulmonology]]
[[Category:Fungal diseases]]
[[Category:Pneumonia|Pneumonia]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
{{WH}}
{{WH}}
{{WS}}
{{WS}}

Latest revision as of 17:46, 18 September 2017

Pneumonia Main Page

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Overview

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Physical Examination

Laboratory Findings

Chest X Ray

CT

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For the main page on pneumonia, click here

For patient information, click here

Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Fungal pneumonia from other Diseases

Epidemiology and Demographics

Risk factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1 Template:WH Template:WS