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__NOTOC__
{{SI}}
{{CMG}}
{{SK}} Synonym 1; Synonym 2; Synonym 3
==Overview==


'''Name of Disease State'''
==Historical Perspective==
*[Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
*In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
*In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].
==Classification==
*[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
:*[group1]
:*[group2]
:*[group3]
*Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
==Pathophysiology==
*The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
*The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
*On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
*On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
==Causes==
* [Disease name] may be caused by either [cause1], [cause2], or [cause3].
* [Disease name] is caused by a mutation in the [gene1], [gene2], or [gene3] gene[s].
* There are no established causes for [disease name].
==Differentiating [disease name] from other Diseases==
*[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
:*[Differential dx1]
:*[Differential dx2]
:*[Differential dx3]
==Epidemiology and Demographics==
* The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
* In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].
===Age===
*Patients of all age groups may develop [disease name].
*[Disease name] is more commonly observed among patients aged [age range] years old.
*[Disease name] is more commonly observed among [elderly patients/young patients/children].
===Gender===
*[Disease name] affects men and women equally.
*[Gender 1] are more commonly affected with [disease name] than [gender 2].
* The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.
===Race===
*There is no racial predilection for [disease name].
*[Disease name] usually affects individuals of the [race 1] race.
*[Race 2] individuals are less likely to develop [disease name].
==Risk Factors==
*Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
== Natural History, Complications and Prognosis==
*The majority of patients with [disease name] remain asymptomatic for [duration/years].
*Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
*If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
*Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
*Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].
== Diagnosis ==
===Diagnostic Criteria===
*The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
:*[criterion 1]
:*[criterion 2]
:*[criterion 3]
:*[criterion 4]
=== Symptoms ===
*[Disease name] is usually asymptomatic.
*Symptoms of [disease name] may include the following:
:*[symptom 1]
:*[symptom 2]
:*[symptom 3]
:*[symptom 4]
:*[symptom 5]
:*[symptom 6]
=== Physical Examination ===
*Patients with [disease name] usually appear [general appearance].
*Physical examination may be remarkable for:
:*[finding 1]
:*[finding 2]
:*[finding 3]
:*[finding 4]
:*[finding 5]
:*[finding 6]
=== Laboratory Findings ===
*There are no specific laboratory findings associated with [disease name].


==== Editor-In-Chief: ====
*A  [positive/negative] [test name] is diagnostic of [disease name].
 
*An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please email [[charlesmichaelgibson@gmail.com]] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
*Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
----
   
 
===Imaging Findings===
= Overview =  
*There are no [imaging study] findings associated with [disease name].
 
===== References =====
*[Imaging study 1] is the imaging modality of choice for [disease name].
----
*On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
= Epidemiology and Demographics =
*[Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].
 
 
===== References =====
----
= Risk Factors =
 
 
===== References =====
----
= Screening =
 
 
===== References =====
----
= Pathophysiology & Etiology=
 
===== References =====
----
= Molecular Biology =
 
 
===== References =====
----
= Genetics =
 
 
===== References =====
----
= Natural History =
 
 
===== References =====
----
= Diagnosis =
 
== Differential Diagnosis ==
 
 
===== References =====
----
== History and Symptoms ==
 
 
===== References =====
----
== Physical Examination ==
 
=== Appearance of the Patient ===
 
=== Eyes ===
 
=== Ear Nose and Throat ===
 
=== Heart ===
 
=== Lungs ===
 
=== Abdomen ===
 
=== Extremities ===
 
=== Neurologic ===
 
=== Other ===
 
===== References =====
----
== Laboratory Findings ==
 
=== Electrolyte and Biomarker Studies ===
 
 
=====References=====
----
 
=== Electrocardiogram ===
 
 
=====References=====
----
 
=== Chest X Ray ===
 
 
=====References=====
----
 
=== MRI and CT ===
 
 
=====References=====
----
 
=== Echocardiography or Ultrasound ===
 
 
=====References=====
----
 
=== Other Imaging Findings ===
 
=====References=====
----
=== Other Diagnostic Studies ===
=== Other Diagnostic Studies ===
*[Disease name] may also be diagnosed using [diagnostic study name].
*Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].
== Treatment ==
=== Medical Therapy ===
*There is no treatment for [disease name]; the mainstay of therapy is supportive care.
*The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
*[Medical therapy 1] acts by [mechanism of action 1].
*Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].
=== Surgery ===
*Surgery is the mainstay of therapy for [disease name].
*[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
*[Surgical procedure] can only be performed for patients with [disease stage] [disease name].
=== Prevention ===
*There are no primary preventive measures available for [disease name].
*Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].


===== References =====
*Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].
----
= Risk Stratification and Prognosis=
 
 
===== References =====
----
= Treatment =
 
 
== Pharmacotherapy ==
 
=== Acute Pharmacotherapies ===
 
===== References =====
----
 
=== Chronic Pharmacotherapies ===
 
 
===== References =====
----
 
== Surgery and Device Based Therapy ==
 
=== Indications for Surgery ===
 
 
===== References =====
----
=== Pre-Operative Assessment ===
 
 
===== References =====
----
 
=== Post-Operative Management ===
 
 
===== References =====
----
=== Transplantation ===
 
 
===== References =====
----
== Primary Prevention ==
 
 
===== References =====
----
== Secondary Prevention ==
 
 
===== References =====
----
== Cost-Effectiveness of Therapy ==
 
 
===== References =====
----
== Future or Investigational Therapies ==
 
 
===== References =====
----
 
==Suggested Revisions to the Current Guidelines==
 
 
== References ==
<biblio>
</biblio>
----
== Acknowledgements ==
The content on this page was first contributed by:
 
List of contributors:
----
== Suggested Reading and Key General References ==
 
== Suggested Links and Web Resources ==
 
== For Patients ==


==References==
{{Reflist|2}}
   
   
 
[[Category:Pulmonology]]
----
{{WikiDoc Sources}}
 
[[Category:Disease]]

Latest revision as of 18:52, 7 June 2016

WikiDoc Resources for Fibrothorax

Articles

Most recent articles on Fibrothorax

Most cited articles on Fibrothorax

Review articles on Fibrothorax

Articles on Fibrothorax in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Fibrothorax

Images of Fibrothorax

Photos of Fibrothorax

Podcasts & MP3s on Fibrothorax

Videos on Fibrothorax

Evidence Based Medicine

Cochrane Collaboration on Fibrothorax

Bandolier on Fibrothorax

TRIP on Fibrothorax

Clinical Trials

Ongoing Trials on Fibrothorax at Clinical Trials.gov

Trial results on Fibrothorax

Clinical Trials on Fibrothorax at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Fibrothorax

NICE Guidance on Fibrothorax

NHS PRODIGY Guidance

FDA on Fibrothorax

CDC on Fibrothorax

Books

Books on Fibrothorax

News

Fibrothorax in the news

Be alerted to news on Fibrothorax

News trends on Fibrothorax

Commentary

Blogs on Fibrothorax

Definitions

Definitions of Fibrothorax

Patient Resources / Community

Patient resources on Fibrothorax

Discussion groups on Fibrothorax

Patient Handouts on Fibrothorax

Directions to Hospitals Treating Fibrothorax

Risk calculators and risk factors for Fibrothorax

Healthcare Provider Resources

Symptoms of Fibrothorax

Causes & Risk Factors for Fibrothorax

Diagnostic studies for Fibrothorax

Treatment of Fibrothorax

Continuing Medical Education (CME)

CME Programs on Fibrothorax

International

Fibrothorax en Espanol

Fibrothorax en Francais

Business

Fibrothorax in the Marketplace

Patents on Fibrothorax

Experimental / Informatics

List of terms related to Fibrothorax

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3

Overview

Historical Perspective

  • [Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
  • In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
  • In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].

Classification

  • [Disease name] may be classified according to [classification method] into [number] subtypes/groups:
  • [group1]
  • [group2]
  • [group3]
  • Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].

Pathophysiology

  • The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
  • The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
  • On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
  • On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Causes

  • [Disease name] may be caused by either [cause1], [cause2], or [cause3].
  • [Disease name] is caused by a mutation in the [gene1], [gene2], or [gene3] gene[s].
  • There are no established causes for [disease name].

Differentiating [disease name] from other Diseases

  • [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
  • [Differential dx1]
  • [Differential dx2]
  • [Differential dx3]

Epidemiology and Demographics

  • The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
  • In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].

Age

  • Patients of all age groups may develop [disease name].
  • [Disease name] is more commonly observed among patients aged [age range] years old.
  • [Disease name] is more commonly observed among [elderly patients/young patients/children].

Gender

  • [Disease name] affects men and women equally.
  • [Gender 1] are more commonly affected with [disease name] than [gender 2].
  • The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

  • There is no racial predilection for [disease name].
  • [Disease name] usually affects individuals of the [race 1] race.
  • [Race 2] individuals are less likely to develop [disease name].

Risk Factors

  • Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].

Natural History, Complications and Prognosis

  • The majority of patients with [disease name] remain asymptomatic for [duration/years].
  • Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
  • If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
  • Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
  • Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].

Diagnosis

Diagnostic Criteria

  • The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
  • [criterion 1]
  • [criterion 2]
  • [criterion 3]
  • [criterion 4]

Symptoms

  • [Disease name] is usually asymptomatic.
  • Symptoms of [disease name] may include the following:
  • [symptom 1]
  • [symptom 2]
  • [symptom 3]
  • [symptom 4]
  • [symptom 5]
  • [symptom 6]

Physical Examination

  • Patients with [disease name] usually appear [general appearance].
  • Physical examination may be remarkable for:
  • [finding 1]
  • [finding 2]
  • [finding 3]
  • [finding 4]
  • [finding 5]
  • [finding 6]

Laboratory Findings

  • There are no specific laboratory findings associated with [disease name].
  • A [positive/negative] [test name] is diagnostic of [disease name].
  • An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
  • Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

Imaging Findings

  • There are no [imaging study] findings associated with [disease name].
  • [Imaging study 1] is the imaging modality of choice for [disease name].
  • On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
  • [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

  • [Disease name] may also be diagnosed using [diagnostic study name].
  • Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].

Treatment

Medical Therapy

  • There is no treatment for [disease name]; the mainstay of therapy is supportive care.
  • The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
  • [Medical therapy 1] acts by [mechanism of action 1].
  • Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].

Surgery

  • Surgery is the mainstay of therapy for [disease name].
  • [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
  • [Surgical procedure] can only be performed for patients with [disease stage] [disease name].

Prevention

  • There are no primary preventive measures available for [disease name].
  • Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].
  • Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].

References