Fexofenadine hydrochloride: Difference between revisions

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{{DrugProjectFormSinglePage
{{DrugProjectFormSinglePage
|authorTag={{KS}}
|authorTag={{KS}}
|aOrAn=a
|genericName=fexofenadine hydrochloride
|adverseReactions=<!--Black Box Warning-->
|aOrAn=an
|drugClass=antihistamine
|indicationType=treatment
|indication=[[Runny nose]],[[Itchy]], watery eyes, [[Sneezing]],[[Itching]] of the nose or throat
|adverseReactions=[[stomach ache]], [[backache]],[[dizziness]] , [[headache]] , [[somnolence]]
[[fatigue]], pain in limb (2.1% )
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
Line 64: Line 69:


* In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
* In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of Fexofenadine
|postmarketing='''Common'''
* Gastrointestinal: [[stomach ache]] (2.1% )
* Musculoskeletal: [[backache]] (2.1% to 2.5% )
* Neurologic: [[dizziness]] (2.1% ), [[headache]] (4.8% to 10.3% ), [[somnolence]]
* Other: [[fatigue]], pain in limb (2.1% )
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''


=====Body as a Whole=====
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of fexofenadine hydrochloride in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of fexofenadine hydrochloride during labor and delivery.
|useInNursing=There is no FDA guidance on the use of fexofenadine hydrochloride with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of fexofenadine hydrochloride with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of fexofenadine hydrochloridewith respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of fexofenadine hydrochloride with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of fexofenadine hydrochloride with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of fexofenadine hydrochloride in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of fexofenadine hydrochloride in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of fexofenadine hydrochloride in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance on the use of fexofenadine hydrochloride in patients who are immunocompromised.




|administration=* Oral


=====Cardiovascular=====


|monitoring=There is limited information regarding <i>Monitoring</i> of fexofenadine hydrochloride in the drug label.




=====Digestive=====




|IVCompat=There is limited information regarding <i>IV Compatibility</i> of fexofenadine hydrochloride in the drug label.


=====Endocrine=====


|overdose=




=====Hematologic and Lymphatic=====






=====Metabolic and Nutritional=====
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.


<!--Pharmacology-->


<!--Drug box 2-->
|mechAction=*


=====Musculoskeletal=====


|structure=*




=====Neurologic=====
|PD=There is limited information regarding <i>Pharmacodynamics</i> of fexofenadine hydrochloride in the drug label.
 
 
 
=====Respiratory=====
 
 
 
=====Skin and Hypersensitivy Reactions=====
 
 
 
=====Special Senses=====
 
 
 
=====Urogenital=====
 
 
 
=====Miscellaneous=====
 
 
 
<!--Drug Interactions-->
|drugInteractions=* Drug
:* Description
 
<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
 
<!--Administration and Monitoring-->
|administration=* Oral
 
* Intravenous
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
 
* Description
 
<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.


<!--Overdosage-->
|overdose====Acute Overdose===


====Signs and Symptoms====
|PK=There is limited information regarding <i>Pharmacokinetics</i> of fexofenadine hydrochloride in the drug label.
 
* Description
 
====Management====
 
* Description
 
===Chronic Overdose===
 
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.
 
<!--Pharmacology-->
 
<!--Drug box 2-->
|drugBox=<!--Mechanism of Action-->
|mechAction=*
 
<!--Structure-->
|structure=*


: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]


<!--Pharmacodynamics-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of fexofenadine hydrochloride in the drug label.
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.


<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.


<!--Nonclinical Toxicology-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of fexofenadine hydrochloride in the drug label.
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.


<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.


<!--How Supplied-->
|howSupplied=*
|howSupplied=*
|packLabel=<!--Patient Counseling Information-->
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of fexofenadine hydrochloride in the drug label.
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.


<!--Precautions with Alcohol-->
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.


<!--Brand Names-->
|alcohol=* Alcohol- fexofenadine hydrochloride interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
|brandNames=* ®<ref>{{Cite web | title =  | url =  }}</ref>


<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>


<!--Drug Shortage Status-->
|drugShortage=
|drugShortage=
}}
}}

Revision as of 15:32, 29 December 2014

Fexofenadine hydrochloride
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Fexofenadine hydrochloride is an antihistamine that is FDA approved for the treatment of Runny nose,Itchy, watery eyes, Sneezing,Itching of the nose or throat. Common adverse reactions include stomach ache, backache,dizziness , headache , somnolence 

fatigue, pain in limb (2.1% ).

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:

Dosing

This image is provided by the National Library of Medicine.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Fexofenadine in adult patients.

Non–Guideline-Supported Use

Indications

  • Hymenoptera immunotherapy, Pretreatment[1]
  • Perennial allergic rhinitis[2]

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Indications

Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:

Dosing

This image is provided by the National Library of Medicine.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Fexofenadine in pediatric patients.

Non–Guideline-Supported Use

Indications

  • Hymenoptera immunotherapy, Pretreatment[1]
  • Perennial allergic rhinitis[2]

Contraindications

There is limited information regarding Fexofenadine hydrochloride Contraindications in the drug label.

Warnings

Do not use

  • If you have ever had an allergic reaction to this product or any of its ingredients.

Ask a doctor before use if you have

  • Kidney disease. Your doctor should determine if you need a different dose.

When using this product

  • Do not take more than directed
  • Do not take at the same time as aluminum or magnesium antacids
  • Do not take with fruit juices (see Directions)

Stop use and ask a doctor if

  • An allergic reaction to this product occurs. Seek medical help right away.

If pregnant or breast-feeding

Ask a health professional before use.

Keep out of reach of children

  • In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Fexofenadine

Postmarketing Experience

Common

Drug Interactions

There is limited information regarding Fexofenadine hydrochloride Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Fexofenadine hydrochloride in women who are pregnant.
Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of fexofenadine hydrochloride in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of fexofenadine hydrochloride during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of fexofenadine hydrochloride with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of fexofenadine hydrochloride with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of fexofenadine hydrochloridewith respect to geriatric patients.

Gender

There is no FDA guidance on the use of fexofenadine hydrochloride with respect to specific gender populations.

Race

There is no FDA guidance on the use of fexofenadine hydrochloride with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of fexofenadine hydrochloride in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of fexofenadine hydrochloride in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of fexofenadine hydrochloride in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance on the use of fexofenadine hydrochloride in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral

Monitoring

There is limited information regarding Monitoring of fexofenadine hydrochloride in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of fexofenadine hydrochloride in the drug label.

Overdosage

There is limited information regarding Chronic Overdose of Fexofenadine hydrochloride in the drug label.

Pharmacology

There is limited information regarding Fexofenadine hydrochloride Pharmacology in the drug label.

Mechanism of Action

Structure

Pharmacodynamics

There is limited information regarding Pharmacodynamics of fexofenadine hydrochloride in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of fexofenadine hydrochloride in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of fexofenadine hydrochloride in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of fexofenadine hydrochloride in the drug label.

How Supplied

Storage

There is limited information regarding Fexofenadine hydrochloride Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Fexofenadine hydrochloride |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Fexofenadine hydrochloride |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of fexofenadine hydrochloride in the drug label.

Precautions with Alcohol

  • Alcohol- fexofenadine hydrochloride interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Fexofenadine hydrochloride Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Fexofenadine hydrochloride Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ 1.0 1.1 Reimers A, Hari Y, Müller U (2000). "Reduction of side-effects from ultrarush immunotherapy with honeybee venom by pretreatment with fexofenadine: a double-blind, placebo-controlled trial". Allergy. 55 (5): 484–8. PMID 10843430 PMID: 10843430 Check |pmid= value (help).
  2. ↑ 2.0 2.1 Bunnag C, Jareoncharsri P, Tunsuriyawong P, Pumhirun P, Limprasertsiri S, Chochaipanichnon L; et al. (2000). "A non-comparative trial of the efficacy and safety of fexofenadine for treatment of perennial allergic rhinitis". Asian Pac J Allergy Immunol. 18 (3): 127–33. PMID 11270466 PMID: 11270466 Check |pmid= value (help).

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