Fetal methotrexate syndrome: Difference between revisions

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====Head====
====Head====
* [[Craniosynostosis]] - some or all of the [[cranial sutures|suture]]s in the [[skull]] of an [[infant]] or child close too early, causing problems with normal [[human brain|brain]] and skull growth.
* [[Craniosynostosis]] - some or all of the [[cranial sutures|suture]]s in the [[skull]] of an [[infant]] or child close too early, causing problems with normal [[human brain|brain]] and skull growth.
====Ears====
====Ear====
* [[Low-set ears]]
* [[Low-set ears]]
====Extremities====
====Extremities====
* [[Club foot]]
* [[Club foot]]

Latest revision as of 15:51, 31 July 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Synonyms and keywords: Aminopterin embryopathy syndrome, aminopterin fetopathy syndrome, aminopterin syndrome, aminopterin fetopathy

Overview

Congenital abnormalities have been documented with methotrexate and aminopterin, and collectively their teratogenic effects have become known as the fetal aminopterin syndrome.

Diagnosis

History

A directed history should be obtained to ascertain prenatal exposure of methotrexate and aminopterin.

Physical Examination

Head

Ear

Extremities

Neurologic

References

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