Familial adenomatous polyposis surgery

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Familial adenomatous polyposis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Surgery is the mainstay of treatment for familial adenomatous polyposis.

Surgery

  • Treatment for FAP depends on the genotype. Most individuals with the APC mutation will develop colon cancer by the age of 40.
  • Prophylatic surgery is generally recommended before the age of 25.
  • There are several surgical options that involve the removal of either the colon or both the colon and rectum.
  • The decision to remove the rectum depends on the number of polyps in the rectum as well as the family history.
  • If the rectum has few polyps, the colon is removed and the small bowel (ileum) is connected to the rectum (ileorectal anastomosis).
  • If the rectum is involved then the colon and rectum are removed and the patient may require an ileostomy or have an ileoanal pouch reconstruction.

References

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