Familial adenomatous polyposis medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
The mainstay of treatment for familial adenomatous polyposis is surgery. However, [[non-steroidal anti-inflammatory drug]]s (NSAIDs) such as sulindac and celecoxib are recommended to decrease the size and number of colon polyps. | The mainstay of treatment for familial adenomatous polyposis is [[surgery]]. However, [[non-steroidal anti-inflammatory drug]]s (NSAIDs) such as [[sulindac]] and [[celecoxib]] are recommended to decrease the size and number of [[colon polyps]]. | ||
==Medical Therapy== | ==Medical Therapy== | ||
*The mainstay of treatment for familial adenomatous polyposis is surgery. | *The mainstay of treatment for familial adenomatous polyposis is [[surgery]]. | ||
*Pharmacologic medical therapies for familial adenomatous polyposis include [[non-steroidal anti-inflammatory drug]]s ([[Non-steroidal anti-inflammatory drug|NSAIDs]]).<ref name="pmid10630758">{{cite journal |vauthors=King JE, Dozois RR, Lindor NM, Ahlquist DA |title=Care of patients and their families with familial adenomatous polyposis |journal=Mayo Clin. Proc. |volume=75 |issue=1 |pages=57–67 |year=2000 |pmid=10630758 |doi=10.4065/75.1.57 |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | *Pharmacologic medical therapies for familial adenomatous polyposis include [[non-steroidal anti-inflammatory drug]]s ([[Non-steroidal anti-inflammatory drug|NSAIDs]]).<ref name="pmid10630758">{{cite journal |vauthors=King JE, Dozois RR, Lindor NM, Ahlquist DA |title=Care of patients and their families with familial adenomatous polyposis |journal=Mayo Clin. Proc. |volume=75 |issue=1 |pages=57–67 |year=2000 |pmid=10630758 |doi=10.4065/75.1.57 |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | ||
** Preferred regimen (1): | ** Preferred regimen (1): [[Sulindac]] | ||
** Preferred regimen (2): | ** Preferred regimen (2): [[Celecoxib]] 400 mg twice daily for 6 months | ||
'''Note (1)''': [[non-steroidal anti-inflammatory drug]]s ([[Non-steroidal anti-inflammatory drug|NSAIDs]]) decrease the size and number of colon polyps. | '''Note (1)''': [[non-steroidal anti-inflammatory drug]]s ([[Non-steroidal anti-inflammatory drug|NSAIDs]]) decrease the size and number of [[colon polyps]]. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 21:40, 30 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
The mainstay of treatment for familial adenomatous polyposis is surgery. However, non-steroidal anti-inflammatory drugs (NSAIDs) such as sulindac and celecoxib are recommended to decrease the size and number of colon polyps.
Medical Therapy
- The mainstay of treatment for familial adenomatous polyposis is surgery.
- Pharmacologic medical therapies for familial adenomatous polyposis include non-steroidal anti-inflammatory drugs (NSAIDs).[1][2]
Note (1): non-steroidal anti-inflammatory drugs (NSAIDs) decrease the size and number of colon polyps.
References
- ↑ King JE, Dozois RR, Lindor NM, Ahlquist DA (2000). "Care of patients and their families with familial adenomatous polyposis". Mayo Clin. Proc. 75 (1): 57–67. doi:10.4065/75.1.57. PMID 10630758.
- ↑ Half, Elizabeth; Bercovich, Dani; Rozen, Paul (2009). "Familial adenomatous polyposis". Orphanet Journal of Rare Diseases. 4 (1): 22. doi:10.1186/1750-1172-4-22. ISSN 1750-1172.