FUT2

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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Galactoside 2-alpha-L-fucosyltransferase 2 is an enzyme that in humans is encoded by the FUT2 gene.[1][2] It affects the Lewis blood group.[citation needed]

Approximately 20% of Caucasians are non-secretors due to the G428A (rs601338) and C571T (rs492602?) nonsense mutations in FUT2 and therefore have strong although not absolute protection from the norovirus GII.4.[citation needed]


References

  1. Ball SP, Tongue N, Gibaud A, Le Pendu J, Mollicone R, Gerard G, Oriol R (Feb 1992). "The human chromosome 19 linkage group FUT1 (H), FUT2 (SE), LE, LU, PEPD, C3, APOC2, D19S7 and D19S9". Ann Hum Genet. 55 (Pt 3): 225–33. doi:10.1111/j.1469-1809.1991.tb00417.x. PMID 1763885.
  2. "Entrez Gene: FUT2 fucosyltransferase 2 (secretor status included)".

Further reading




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