FUT1

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene.

Further reading

• Ball SP, Tongue N, Gibaud A, Le Pendu J, Mollicone R, Gérard G, Oriol R (July 1991). "The human chromosome 19 linkage group FUT1 (H), FUT2 (SE), LE, LU, PEPD, C3, APOC2, D19S7 and D19S9". Annals of Human Genetics. 55 (Pt 3): 225–33. doi:10.1111/j.1469-1809.1991.tb00417.x. PMID 1763885.
• Larsen RD, Ernst LK, Nair RP, Lowe JB (September 1990). "Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen". Proceedings of the National Academy of Sciences of the United States of America. 87 (17): 6674–8. doi:10.1073/pnas.87.17.6674. PMC 54599. PMID 2118655.
• Reguigne-Arnould I, Couillin P, Mollicone R, Fauré S, Fletcher A, Kelly RJ, Lowe JB, Oriol R (1995). "Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19". Cytogenetics and Cell Genetics. 71 (2): 158–62. doi:10.1159/000134098. PMID 7656588.
• Bruneau N, Lombardo D (June 1995). "Chaperone function of a Grp 94-related protein for folding and transport of the pancreatic bile salt-dependent lipase". The Journal of Biological Chemistry. 270 (22): 13524–33. doi:10.1074/jbc.270.22.13524. PMID 7768954.
• Kelly RJ, Ernst LK, Larsen RD, Bryant JG, Robinson JS, Lowe JB (June 1994). "Molecular basis for H blood group deficiency in Bombay (Oh) and para-Bombay individuals". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 5843–7. doi:10.1073/pnas.91.13.5843. PMC 44093. PMID 7912436.
• Koda Y, Soejima M, Kimura H (March 1997). "Structure and expression of H-type GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase gene (FUT1). Two transcription start sites and alternative splicing generate several forms of FUT1 mRNA". The Journal of Biological Chemistry. 272 (11): 7501–5. doi:10.1074/jbc.272.11.7501. PMID 9054453.
• Wagner FF, Flegel WA (March 1997). "Polymorphism of the h allele and the population frequency of sporadic nonfunctional alleles". Transfusion. 37 (3): 284–90. doi:10.1046/j.1537-2995.1997.37397240210.x. PMID 9122901.
• Kaneko M, Nishihara S, Shinya N, Kudo T, Iwasaki H, Seno T, Okubo Y, Narimatsu H (July 1997). "Wide variety of point mutations in the H gene of Bombay and para-Bombay individuals that inactivate H enzyme". Blood. 90 (2): 839–49. PMID 9226185.
• Koda Y, Soejima M, Johnson PH, Smart E, Kimura H (September 1997). "Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system". Biochemical and Biophysical Research Communications. 238 (1): 21–5. doi:10.1006/bbrc.1997.7232. PMID 9299444.
• Koda Y, Soejima M, Kimura H (September 1998). "Changing transcription start sites in H-type alpha(1,2)fucosyltransferase gene (FUT1) during differentiation of the human erythroid lineage". European Journal of Biochemistry / FEBS. 256 (2): 379–87. doi:10.1046/j.1432-1327.1998.2560379.x. PMID 9760178.
• Roos C, Kolmer M, Mattila P, Renkonen R (February 2002). "Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism". The Journal of Biological Chemistry. 277 (5): 3168–75. doi:10.1074/jbc.M107927200. PMID 11698403.
• Yip SP, Chee KY, Chan PY, Chow EY, Wong HF (October 2002). "Molecular genetic analysis of para-Bombay phenotypes in Chinese: a novel non-functional FUT1 allele is identified". Vox Sanguinis. 83 (3): 258–62. doi:10.1046/j.1423-0410.2002.00184.x. PMID 12366770.
• López-Ferrer A, de Bolós C (January 2002). "The expression of human FUT1 in HT-29/M3 colon cancer cells instructs the glycosylation of MUC1 and MUC5AC apomucins". Glycoconjugate Journal. 19 (1): 13–21. doi:10.1023/A:1022576712961. PMID 12652076.
• Shi S, Stanley P (April 2003). "Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways". Proceedings of the National Academy of Sciences of the United States of America. 100 (9): 5234–9. doi:10.1073/pnas.0831126100. PMC 154328. PMID 12697902.
• Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (June 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Guo ZH, Xiang D, Zhu ZY, Wang JL, Zhang JM, Liu X, Shen W, Chen HP (October 2004). "[Analysis on FUT1 and FUT2 gene of 10 para-Bombay individuals in China]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics. 21 (5): 417–21. PMID 15476160.
• Yan L, Zhu F, Xu X, Hong X, Lv Q (May 2005). "Molecular basis for para-Bombay phenotypes in Chinese persons, including a novel nonfunctional FUT1 allele". Transfusion. 45 (5): 725–30. doi:10.1111/j.1537-2995.2005.04305.x. PMID 15847661.
• Mejías-Luque R, López-Ferrer A, Garrido M, Fabra A, de Bolós C (July 2007). "Changes in the invasive and metastatic capacities of HT-29/M3 cells induced by the expression of fucosyltransferase 1". Cancer Science. 98 (7): 1000–5. doi:10.1111/j.1349-7006.2007.00484.x. PMID 17459061.