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{{distinguish|France}}
{{PBB_Controls
{{Infobox_gene}}
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'''Fanconi anemia group E protein''' is a [[protein]] that in humans is encoded by the ''FANCE'' [[gene]].<ref name="pmid7662964">{{cite journal |vauthors=Joenje H, Lo ten Foe JR, Oostra AB, van Berkel CG, Rooimans MA, Schroeder-Kurth T, Wegner RD, Gille JJ, Buchwald M, Arwert F | title = Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype | journal = Blood | volume = 86 | issue = 6 | pages = 2156–60 | date = Oct 1995 | pmid = 7662964 | pmc =  | doi =  }}</ref><ref name="pmid11001585">{{cite journal |vauthors=de Winter JP, Léveillé F, van Berkel CG, Rooimans MA, van Der Weel L, Steltenpool J, Demuth I, Morgan NV, Alon N, Bosnoyan-Collins L, Lightfoot J, Leegwater PA, Waisfisz Q, Komatsu K, Arwert F, Pronk JC, Mathew CG, Digweed M, Buchwald M, Joenje H | title = Isolation of a cDNA representing the Fanconi anemia complementation group E gene | journal = Am J Hum Genet | volume = 67 | issue = 5 | pages = 1306–8 | date = Nov 2000 | pmid = 11001585 | pmc = 1288571 | doi = 10.1016/S0002-9297(07)62959-0 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: FANCE Fanconi anemia, complementation group E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2178| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_FANCE_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2ilr.
| PDB = {{PDB2|2ilr}}
| Name = Fanconi anemia, complementation group E
| HGNCid = 3586
| Symbol = FANCE
| AltSymbols =; FACE; FAE
| OMIM = 600901
| ECnumber = 
| Homologene = 11066
| MGIid = 1920025
| GeneAtlas_image1 = PBB_GE_FANCE_220255_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006281 |text = DNA repair}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2178
    | Hs_Ensembl = ENSG00000112039
    | Hs_RefseqProtein = NP_068741
    | Hs_RefseqmRNA = NM_021922
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 35528116
    | Hs_GenLoc_end = 35542859
    | Hs_Uniprot = Q9HB96
    | Mm_EntrezGene = 72775
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = XM_915490
    | Mm_RefseqProtein = XP_920583
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Fanconi anemia, complementation group E''', also known as '''FANCE''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: FANCE Fanconi anemia, complementation group E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2178| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.<ref name="entrez" />
{{PBB_Summary
 
| section_title =
== Interactions ==
| summary_text = The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.<ref name="entrez">{{cite web | title = Entrez Gene: FANCE Fanconi anemia, complementation group E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2178| accessdate = }}</ref>
 
}}
FANCE has been shown to [[Protein-protein interaction|interact]] with:
* [[FANCA]],<ref name = pmid12239156/><ref name = pmid11157805/><ref name = pmid12093742/><ref name = pmid12973351>{{cite journal | vauthors = Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W | title = A novel ubiquitin ligase is deficient in Fanconi anemia | journal = Nat. Genet. | volume = 35 | issue = 2 | pages = 165–70 | date = Oct 2003 | pmid = 12973351 | doi = 10.1038/ng1241 }}</ref>
* [[FANCD2]],<ref name = pmid12093742/><ref name = pmid12649160/><ref name = pmid15115758>{{cite journal |vauthors=Hussain S, Wilson JB, Medhurst AL, Hejna J, Witt E, Ananth S, Davies A, Masson JY, Moses R, West SC, de Winter JP, Ashworth A, Jones NJ, Mathew CG | title = Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways | journal = Hum. Mol. Genet. | volume = 13 | issue = 12 | pages = 1241–8 | date = Jun 2004 | pmid = 15115758 | doi = 10.1093/hmg/ddh135 }}</ref>
* [[FANCF]]<ref name = pmid12093742/><ref name = pmid15262960/>
* [[FANCG]],<ref name = pmid12239156/><ref name = pmid11157805/><ref name = pmid12093742/> and
* [[Fanconi anemia, complementation group C|FANCC]].<ref name = pmid12239156>{{cite journal |vauthors=Taniguchi T, D'Andrea AD | title = The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC | journal = Blood | volume = 100 | issue = 7 | pages = 2457–62 | date = Oct 2002 | pmid = 12239156 | doi = 10.1182/blood-2002-03-0860 }}</ref><ref name = pmid11157805>{{cite journal |vauthors=Medhurst AL, Huber PA, Waisfisz Q, de Winter JP, Mathew CG | title = Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway | journal = Hum. Mol. Genet. | volume = 10 | issue = 4 | pages = 423–9 | date = Feb 2001 | pmid = 11157805 | doi = 10.1093/hmg/10.4.423}}</ref><ref name = pmid12093742>{{cite journal |vauthors=Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, de Winter J, Joenje H, Gergely F, Patel KJ | title = FANCE: the link between Fanconi anaemia complex assembly and activity | journal = EMBO J. | volume = 21 | issue = 13 | pages = 3414–23 | date = Jul 2002 | pmid = 12093742 | pmc = 125396 | doi = 10.1093/emboj/cdf355 }}</ref><ref name = pmid12649160>{{cite journal |vauthors=Gordon SM, Buchwald M | title = Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems | journal = Blood | volume = 102 | issue = 1 | pages = 136–41 | date = Jul 2003 | pmid = 12649160 | doi = 10.1182/blood-2002-11-3517 }}</ref><ref name = pmid15262960>{{cite journal |vauthors=Léveillé F, Blom E, Medhurst AL, Bier P, Laghmani el H, Johnson M, Rooimans MA, Sobeck A, Waisfisz Q, Arwert F, Patel KJ, Hoatlin ME, Joenje H, de Winter JP | title = The Fanconi anemia gene product FANCF is a flexible adaptor protein | journal = J. Biol. Chem. | volume = 279 | issue = 38 | pages = 39421–30 | date = Sep 2004 | pmid = 15262960 | doi = 10.1074/jbc.M407034200 }}</ref>


==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
*{{cite journal |vauthors=Wegner RD, Henrichs I, Joenje H, Schroeder-Kurth T | title = Fanconi anemia complementation group E: clinical and cytogenetic data of the first patient | journal = Clin. Genet. | volume = 50 | issue = 6 | pages = 479–82 | year = 1997 | pmid = 9147877 | doi = 10.1111/j.1399-0004.1996.tb02716.x }}
| citations =
*{{cite journal |vauthors=Joenje H, Oostra AB, Wijker M, di Summa FM, van Berkel CG, Rooimans MA, Ebell W, van Weel M, Pronk JC, Buchwald M, Arwert F | title = Evidence for at least eight Fanconi anemia genes | journal = Am. J. Hum. Genet. | volume = 61 | issue = 4 | pages = 940–4 | year = 1997 | pmid = 9382107 | pmc = 1715980 | doi = 10.1086/514881 }}
*{{cite journal | author=Joenje H, Lo ten Foe JR, Oostra AB, ''et al.'' |title=Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype. |journal=Blood |volume=86 |issue= 6 |pages= 2156-60 |year= 1995 |pmid= 7662964 |doi=  }}
*{{cite journal |vauthors=Waisfisz Q, Saar K, Morgan NV, Altay C, Leegwater PA, de Winter JP, Komatsu K, Evans GR, Wegner RD, Reis A, Joenje H, Arwert F, Mathew CG, Pronk JC, Digweed M | title = The Fanconi anemia group E gene, FANCE, maps to chromosome 6p | journal = Am. J. Hum. Genet. | volume = 64 | issue = 5 | pages = 1400–5 | year = 1999 | pmid = 10205272 | pmc = 1377877 | doi = 10.1086/302385 }}
*{{cite journal  | author=Wegner RD, Henrichs I, Joenje H, Schroeder-Kurth T |title=Fanconi anemia complementation group E: clinical and cytogenetic data of the first patient. |journal=Clin. Genet. |volume=50 |issue= 6 |pages= 479-82 |year= 1997 |pmid= 9147877 |doi= }}
*{{cite journal |vauthors=Medhurst AL, Huber PA, Waisfisz Q, de Winter JP, Mathew CG | title = Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway | journal = Hum. Mol. Genet. | volume = 10 | issue = 4 | pages = 423–9 | year = 2001 | pmid = 11157805 | doi = 10.1093/hmg/10.4.423 }}
*{{cite journal | author=Joenje H, Oostra AB, Wijker M, ''et al.'' |title=Evidence for at least eight Fanconi anemia genes. |journal=Am. J. Hum. Genet. |volume=61 |issue= 4 |pages= 940-4 |year= 1997 |pmid= 9382107 |doi= }}
*{{cite journal |vauthors=Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, de Winter J, Joenje H, Gergely F, Patel KJ | title = FANCE: the link between Fanconi anaemia complex assembly and activity | journal = EMBO J. | volume = 21 | issue = 13 | pages = 3414–23 | year = 2002 | pmid = 12093742 | pmc = 125396 | doi = 10.1093/emboj/cdf355 }}
*{{cite journal | author=Waisfisz Q, Saar K, Morgan NV, ''et al.'' |title=The Fanconi anemia group E gene, FANCE, maps to chromosome 6p. |journal=Am. J. Hum. Genet. |volume=64 |issue= 5 |pages= 1400-5 |year= 1999 |pmid= 10205272 |doi= }}
*{{cite journal |vauthors=Taniguchi T, D'Andrea AD | title = The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC | journal = Blood | volume = 100 | issue = 7 | pages = 2457–62 | year = 2002 | pmid = 12239156 | doi = 10.1182/blood-2002-03-0860 }}
*{{cite journal  | author=de Winter JP, Léveillé F, van Berkel CG, ''et al.'' |title=Isolation of a cDNA representing the Fanconi anemia complementation group E gene. |journal=Am. J. Hum. Genet. |volume=67 |issue= 5 |pages= 1306-8 |year= 2000 |pmid= 11001585 |doi=  }}
*{{cite journal |vauthors=Gordon SM, Buchwald M | title = Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems | journal = Blood | volume = 102 | issue = 1 | pages = 136–41 | year = 2003 | pmid = 12649160 | doi = 10.1182/blood-2002-11-3517 }}
*{{cite journal | author=Medhurst AL, Huber PA, Waisfisz Q, ''et al.'' |title=Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 423-9 |year= 2001 |pmid= 11157805 |doi= }}
*{{cite journal |vauthors=Meetei AR, Sechi S, Wallisch M, Yang D, Young MK, Joenje H, Hoatlin ME, Wang W | title = A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome | journal = Mol. Cell. Biol. | volume = 23 | issue = 10 | pages = 3417–26 | year = 2003 | pmid = 12724401 | pmc = 164758 | doi = 10.1128/MCB.23.10.3417-3426.2003 }}
*{{cite journal | author=Pace P, Johnson M, Tan WM, ''et al.'' |title=FANCE: the link between Fanconi anaemia complex assembly and activity. |journal=EMBO J. |volume=21 |issue= 13 |pages= 3414-23 |year= 2002 |pmid= 12093742 |doi= 10.1093/emboj/cdf355 }}
*{{cite journal | vauthors = Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W | title = A novel ubiquitin ligase is deficient in Fanconi anemia | journal = Nat. Genet. | volume = 35 | issue = 2 | pages = 165–70 | year = 2003 | pmid = 12973351 | doi = 10.1038/ng1241 }}
*{{cite journal | author=Taniguchi T, D'Andrea AD |title=The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC. |journal=Blood |volume=100 |issue= 7 |pages= 2457-62 |year= 2002 |pmid= 12239156 |doi= 10.1182/blood-2002-03-0860 }}
*{{cite journal |vauthors=Hussain S, Wilson JB, Medhurst AL, Hejna J, Witt E, Ananth S, Davies A, Masson JY, Moses R, West SC, de Winter JP, Ashworth A, Jones NJ, Mathew CG | title = Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways | journal = Hum. Mol. Genet. | volume = 13 | issue = 12 | pages = 1241–8 | year = 2004 | pmid = 15115758 | doi = 10.1093/hmg/ddh135 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal |vauthors=Wang X, Andreassen PR, D'Andrea AD | title = Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin | journal = Mol. Cell. Biol. | volume = 24 | issue = 13 | pages = 5850–62 | year = 2004 | pmid = 15199141 | pmc = 480901 | doi = 10.1128/MCB.24.13.5850-5862.2004 }}
*{{cite journal  | author=Gordon SM, Buchwald M |title=Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems. |journal=Blood |volume=102 |issue= 1 |pages= 136-41 |year= 2003 |pmid= 12649160 |doi= 10.1182/blood-2002-11-3517 }}
*{{cite journal |vauthors=Léveillé F, Blom E, Medhurst AL, Bier P, Laghmani el H, Johnson M, Rooimans MA, Sobeck A, Waisfisz Q, Arwert F, Patel KJ, Hoatlin ME, Joenje H, de Winter JP | title = The Fanconi anemia gene product FANCF is a flexible adaptor protein | journal = J. Biol. Chem. | volume = 279 | issue = 38 | pages = 39421–30 | year = 2004 | pmid = 15262960 | doi = 10.1074/jbc.M407034200 }}
*{{cite journal | author=Meetei AR, Sechi S, Wallisch M, ''et al.'' |title=A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. |journal=Mol. Cell. Biol. |volume=23 |issue= 10 |pages= 3417-26 |year= 2003 |pmid= 12724401 |doi= }}
*{{cite journal |vauthors=Meetei AR, Levitus M, Xue Y, Medhurst AL, Zwaan M, Ling C, Rooimans MA, Bier P, Hoatlin M, Pals G, de Winter JP, Wang W, Joenje H | title = X-linked inheritance of Fanconi anemia complementation group B | journal = Nat. Genet. | volume = 36 | issue = 11 | pages = 1219–24 | year = 2004 | pmid = 15502827 | doi = 10.1038/ng1458 }}
*{{cite journal | author=Meetei AR, de Winter JP, Medhurst AL, ''et al.'' |title=A novel ubiquitin ligase is deficient in Fanconi anemia. |journal=Nat. Genet. |volume=35 |issue= 2 |pages= 165-70 |year= 2003 |pmid= 12973351 |doi= 10.1038/ng1241 }}
*{{cite journal |vauthors=Meetei AR, Medhurst AL, Ling C, Xue Y, Singh TR, Bier P, Steltenpool J, Stone S, Dokal I, Mathew CG, Hoatlin M, Joenje H, de Winter JP, Wang W | title = A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M | journal = Nat. Genet. | volume = 37 | issue = 9 | pages = 958–63 | year = 2005 | pmid = 16116422 | pmc = 2704909 | doi = 10.1038/ng1626 }}
*{{cite journal | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal |vauthors=Gordon SM, Alon N, Buchwald M | title = FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway | journal = J. Biol. Chem. | volume = 280 | issue = 43 | pages = 36118–25 | year = 2006 | pmid = 16127171 | doi = 10.1074/jbc.M507758200 }}
*{{cite journal  | author=Hussain S, Wilson JB, Medhurst AL, ''et al.'' |title=Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. |journal=Hum. Mol. Genet. |volume=13 |issue= 12 |pages= 1241-8 |year= 2004 |pmid= 15115758 |doi= 10.1093/hmg/ddh135 }}
*{{cite journal | author=Wang X, Andreassen PR, D'Andrea AD |title=Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. |journal=Mol. Cell. Biol. |volume=24 |issue= 13 |pages= 5850-62 |year= 2004 |pmid= 15199141 |doi= 10.1128/MCB.24.13.5850-5862.2004 }}
*{{cite journal | author=Léveillé F, Blom E, Medhurst AL, ''et al.'' |title=The Fanconi anemia gene product FANCF is a flexible adaptor protein. |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 39421-30 |year= 2004 |pmid= 15262960 |doi= 10.1074/jbc.M407034200 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Meetei AR, Levitus M, Xue Y, ''et al.'' |title=X-linked inheritance of Fanconi anemia complementation group B. |journal=Nat. Genet. |volume=36 |issue= 11 |pages= 1219-24 |year= 2004 |pmid= 15502827 |doi= 10.1038/ng1458 }}
*{{cite journal | author=Meetei AR, Medhurst AL, Ling C, ''et al.'' |title=A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. |journal=Nat. Genet. |volume=37 |issue= 9 |pages= 958-63 |year= 2005 |pmid= 16116422 |doi= 10.1038/ng1626 }}
*{{cite journal | author=Gordon SM, Alon N, Buchwald M |title=FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway. |journal=J. Biol. Chem. |volume=280 |issue= 43 |pages= 36118-25 |year= 2006 |pmid= 16127171 |doi= 10.1074/jbc.M507758200 }}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=2178}}


{{protein-stub}}
{{Gene-6-stub}}
{{WikiDoc Sources}}

Revision as of 04:38, 31 August 2017

Not to be confused with France.
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Fanconi anemia group E protein is a protein that in humans is encoded by the FANCE gene.[1][2][3]

Function

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.[3]

Interactions

FANCE has been shown to interact with:

References

  1. ↑ Joenje H, Lo ten Foe JR, Oostra AB, van Berkel CG, Rooimans MA, Schroeder-Kurth T, Wegner RD, Gille JJ, Buchwald M, Arwert F (Oct 1995). "Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype". Blood. 86 (6): 2156–60. PMID 7662964.
  2. ↑ de Winter JP, Léveillé F, van Berkel CG, Rooimans MA, van Der Weel L, Steltenpool J, Demuth I, Morgan NV, Alon N, Bosnoyan-Collins L, Lightfoot J, Leegwater PA, Waisfisz Q, Komatsu K, Arwert F, Pronk JC, Mathew CG, Digweed M, Buchwald M, Joenje H (Nov 2000). "Isolation of a cDNA representing the Fanconi anemia complementation group E gene". Am J Hum Genet. 67 (5): 1306–8. doi:10.1016/S0002-9297(07)62959-0. PMC 1288571. PMID 11001585.
  3. ↑ 3.0 3.1 "Entrez Gene: FANCE Fanconi anemia, complementation group E".
  4. ↑ 4.0 4.1 4.2 Taniguchi T, D'Andrea AD (Oct 2002). "The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC". Blood. 100 (7): 2457–62. doi:10.1182/blood-2002-03-0860. PMID 12239156.
  5. ↑ 5.0 5.1 5.2 Medhurst AL, Huber PA, Waisfisz Q, de Winter JP, Mathew CG (Feb 2001). "Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway". Hum. Mol. Genet. 10 (4): 423–9. doi:10.1093/hmg/10.4.423. PMID 11157805.
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, de Winter J, Joenje H, Gergely F, Patel KJ (Jul 2002). "FANCE: the link between Fanconi anaemia complex assembly and activity". EMBO J. 21 (13): 3414–23. doi:10.1093/emboj/cdf355. PMC 125396. PMID 12093742.
  7. ↑ Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W (Oct 2003). "A novel ubiquitin ligase is deficient in Fanconi anemia". Nat. Genet. 35 (2): 165–70. doi:10.1038/ng1241. PMID 12973351.
  8. ↑ 8.0 8.1 Gordon SM, Buchwald M (Jul 2003). "Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems". Blood. 102 (1): 136–41. doi:10.1182/blood-2002-11-3517. PMID 12649160.
  9. ↑ Hussain S, Wilson JB, Medhurst AL, Hejna J, Witt E, Ananth S, Davies A, Masson JY, Moses R, West SC, de Winter JP, Ashworth A, Jones NJ, Mathew CG (Jun 2004). "Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways". Hum. Mol. Genet. 13 (12): 1241–8. doi:10.1093/hmg/ddh135. PMID 15115758.
  10. ↑ 10.0 10.1 Léveillé F, Blom E, Medhurst AL, Bier P, Laghmani el H, Johnson M, Rooimans MA, Sobeck A, Waisfisz Q, Arwert F, Patel KJ, Hoatlin ME, Joenje H, de Winter JP (Sep 2004). "The Fanconi anemia gene product FANCF is a flexible adaptor protein". J. Biol. Chem. 279 (38): 39421–30. doi:10.1074/jbc.M407034200. PMID 15262960.

Further reading


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