FABP7: Difference between revisions
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Revision as of 17:16, 4 September 2012
Fatty acid binding protein 7, brain | |||||||||||||
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PDB rendering based on 1fdq. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | FABP7 ; B-FABP; BLBP; DKFZp547J2313; FABPB; MRG | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 37880 | ||||||||||||
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RNA expression pattern | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
Fatty acid binding protein 7, brain, also known as FABP7, is a human gene.[1] The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.[1]
References
Further reading
- Börchers T, Hohoff C, Buhlmann C, Spener F (1997). "Heart-type fatty acid binding protein - involvement in growth inhibition and differentiation". Prostaglandins Leukot. Essent. Fatty Acids. 57 (1): 77–84. PMID 9250612.
- Xu LZ, Sánchez R, Sali A, Heintz N (1996). "Ligand specificity of brain lipid-binding protein". J. Biol. Chem. 271 (40): 24711–9. PMID 8798739.
- Young JK, Baker JH, Muller T (1997). "Immunoreactivity for brain-fatty acid binding protein in gomori-positive astrocytes". Glia. 16 (3): 218–26. doi:10.1002/(SICI)1098-1136(199603)16:3<218::AID-GLIA4>3.0.CO;2-Y. PMID 8833192.
- Shi YE, Ni J, Xiao G; et al. (1997). "Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG". Cancer Res. 57 (15): 3084–91. PMID 9242429.
- Shimizu F, Watanabe TK, Shinomiya H; et al. (1997). "Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP)". Biochim. Biophys. Acta. 1354 (1): 24–8. PMID 9375786.
- Godbout R, Bisgrove DA, Shkolny D, Day RS (1998). "Correlation of B-FABP and GFAP expression in malignant glioma". Oncogene. 16 (15): 1955–62. doi:10.1038/sj.onc.1201740. PMID 9591779.
- Pu L, Igbavboa U, Wood WG; et al. (1999). "Expression of fatty acid binding proteins is altered in aged mouse brain". Mol. Cell. Biochem. 198 (1–2): 69–78. PMID 10497880.
- Balendiran GK, Schnutgen F, Scapin G; et al. (2000). "Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein". J. Biol. Chem. 275 (35): 27045–54. doi:10.1074/jbc.M003001200. PMID 10854433.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Rademacher M, Zimmerman AW, Rüterjans H; et al. (2003). "Solution structure of fatty acid-binding protein from human brain". Mol. Cell. Biochem. 239 (1–2): 61–8. PMID 12479569.
- Miller SJ, Li H, Rizvi TA; et al. (2003). "Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis". Mol. Cell. Biol. 23 (6): 2213–24. PMID 12612091.
- Sánchez-Font MF, Bosch-Comas A, Gonzàlez-Duarte R, Marfany G (2003). "Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance". Nucleic Acids Res. 31 (11): 2769–77. PMID 12771203.
- Wang M, Liu YE, Goldberg ID, Shi YE (2004). "Induction of mammary gland differentiation in transgenic mice by the fatty acid-binding protein MRG". J. Biol. Chem. 278 (47): 47319–25. doi:10.1074/jbc.M308131200. PMID 12975368.
- Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Liang Y, Diehn M, Watson N; et al. (2005). "Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme". Proc. Natl. Acad. Sci. U.S.A. 102 (16): 5814–9. doi:10.1073/pnas.0402870102. PMID 15827123.
- Liang Y, Bollen AW, Aldape KD, Gupta N (2006). "Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma". BMC Cancer. 6: 97. doi:10.1186/1471-2407-6-97. PMID 16623952.
- Kaloshi G, Mokhtari K, Carpentier C; et al. (2007). "FABP7 expression in glioblastomas: relation to prognosis, invasion and EGFR status". J. Neurooncol. 84 (3): 245–8. doi:10.1007/s11060-007-9377-4. PMID 17415524.
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