Erythromycin (oral): Difference between revisions
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==Overview== | ==Overview== | ||
'''Erythromycin''' is a [[macrolide]] [[antibiotic]] that has an antimicrobial spectrum similar to or slightly wider than that of [[penicillin]], and is often [[prescription drug|prescribed]] for people who have an [[allergy]] to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including ''[[Mycoplasma]]'' and [[legionellosis]]. It was first marketed by [[Eli Lilly and Company]], and it is today commonly known as EES (erythromycin ethylsuccinate, an ester [[prodrug]] that is commonly administered). It is also occasionally used as a [[prokinetic]] agent. | |||
In structure, this macrocyclic compound contains a 14-membered [[lactone]] ring with ten asymmetric centers and two sugars (<small>L</small>-[[cladinose]] and <small>D</small>-[[desosamine]]), making it a compound very difficult to produce via synthetic methods. | |||
Erythromycin is produced from a strain of the actinomycete ''[[Saccharopolyspora erythraea]]''. | |||
==Category== | ==Category== | ||
Revision as of 22:43, 8 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]
Overview
Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often prescribed for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including Mycoplasma and legionellosis. It was first marketed by Eli Lilly and Company, and it is today commonly known as EES (erythromycin ethylsuccinate, an ester prodrug that is commonly administered). It is also occasionally used as a prokinetic agent.
In structure, this macrocyclic compound contains a 14-membered lactone ring with ten asymmetric centers and two sugars (L-cladinose and D-desosamine), making it a compound very difficult to produce via synthetic methods.
Erythromycin is produced from a strain of the actinomycete Saccharopolyspora erythraea.
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US Brand Names
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages