Eosinophilic esophagitis: Difference between revisions

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Revision as of 14:13, 22 August 2014

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Eosinophilic esophagitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Future or Investigational Therapies

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+__NOTOC__
+'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
+{{Eosinophilic esophagitis}}
+{{CMG}}
+==[[Eosinophilic esophagitis overview|Overview]]==
-==Overview==
+==[[Eosinophilic esophagitis historical perspective|Historical Perspective]]==
-{{SI}}
-'''Eosinophilic esophagitis''' is an [[allergy|allergic]] inflammatory condition of the [[esophagus]]. Symptoms are [[chest pain]] or [[heartburn]] and occasionally [[dysphagia]], or difficulty in [[swallow]]ing.  The [[disease]] was first described in children but occurs in adults as well.
-[[Image:Multi ring esophagus.jpg|thumb|center|[[Endoscopic]] image of [[esophagus]] in a case of eosinophilic esophagitis.  Concentric rings are termed [[Vertebrate trachea|trachealization]] of the esophagus.]]
+==[[Eosinophilic esophagitis classification|Classification]]==
-Diagnosis is obtained during an upper GI endoscopy where [[biopsies]] are taken of the esophagus.  At the time of [[endoscopy]], ridges or [[furrow]]s may be seen in the esophagus wall.  Sometimes, multiple rings may occur in the esophagus, leading to the term "multi-ring esophagus" or "feline esophagus" due to the similarity in the rings of the cat esophagus.  A high number of eosinophils are seen on microscopic examination of the biopsy specimens.
+==[[Eosinophilic esophagitis pathophysiology|Pathophysiology]]==
-Skin testing can help identify which foods might contribute to this disease, but often skin testing implicates foods that are not involved.  Common [[allergen]]s in the GI tract are cow's milk, soy, egg and wheat.
-[[Image:Eosinophilic esophagiits ba swallow.jpg|thumb|center|150px|[[Barium swallow]] of the esophagus, showing multiple rings associated with eosinophilic esophagitis.]]
+==[[Eosinophilic esophagitis causes|Causes]]==
-Treatment strategies include removal of the offending food, [[proton pump inhibitor]]s to decrease acidity in the stomach that may reflux into the esophagus, inhaled steroid puffers taken orally and swallowed, anti-histamines, H2-receptor blockers such as [[cimetidine]], [[leukotriene]] modifiers such as [[montelukast]], and, in investigational reports, the anti-IL5 [[monoclonal antibody]] [[mepolizumab]].  Refractory patients may require oral [[steroid]] medications.
+==[[Eosinophilic esophagitis differential diagnosis|Differentiating Eosinophilic esophagitis from other Diseases]]==
-[[Image:Eosinophilic esophagiits path.jpg|thumb|center|150px|[[H&E]] stain of [[esophagus]] [[biopsy]] showing eosinophilic esophagitis, manifested by an infiltration of [[eosinophils]] in the [[lamina propria]]]]
+==[[Eosinophilic esophagitis epidemiology and demographics|Epidemiology and Demographics]]==
-==External links==
+==[[Eosinophilic esophagitis risk factors|Risk Factors]]==
-*[http://www.apfed.org/ American Partnership for Eosinophilic Disorders]
-*[http://www.cincinnatichildrens.org/svc/alpha/e/eosinophilic/ Cincinnati Center for Eosinophilic Disorders]
+==[[Eosinophilic esophagitis screening|Screening]]==
+==[[Eosinophilic esophagitis natural history|Natural History, Complications and Prognosis]]==
+==Diagnosis==
+[[Eosinophilic esophagitis history and symptoms|History and Symptoms]] | [[Eosinophilic esophagitis physical examination|Physical Examination]] | [[Eosinophilic esophagitis laboratory tests|Laboratory Findings]]
+==Treatment==
+[[Eosinophilic esophagitis medical therapy|Medical Therapy]] | [[Eosinophilic esophagitis primary prevention|Primary Prevention]]  |  [[Eosinophilic esophagitis secondary prevention|Secondary Prevention]]  |  [[Eosinophilic esophagitis future or investigational therapies|Future or Investigational Therapies]]
 {{Gastroenterology}}
 [[Category:Gastroenterology]]
-[[he:אאוזנופיליק אזופגטיס]]
 {{WH}}
 {{WikiDoc Sources}}

Eosinophilic esophagitis: Difference between revisions

Revision as of 14:13, 22 August 2014

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