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| | __NOTOC__ |
| {{Infobox_Disease | | | {{Infobox_Disease | |
| Name = {{PAGENAME}} | | | Name = {{PAGENAME}} | |
| Image = | | | Image = | |
| Caption = | | | Caption = | |
| DiseasesDB = | | | DiseasesDB = 4328 | |
| ICD10 = | | | ICD10 = | |
| ICD9 = | | | ICD9 = | |
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| OMIM = | | | OMIM = | |
| MedlinePlus = | | | MedlinePlus = | |
| eMedicineSubj = |
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| eMedicineTopic = |
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| MeshID = | | | MeshID = | |
| }} | | }} |
| {{SI}} | | {{Eosinophilia}} |
| {{CMG}}; {{AOEIC}} {{LG}} | | {{CMG}}; {{AOEIC}} {{LG}}, George Leef MD |
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| == Overview ==
| | {{SK}} Eosinophil count raised (peripheral blood), hereditary eosinophilia |
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| *Eosinphilia refers to a group of idiopathic, neoplastic, infectious and allergic illnesses
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| *Eosinphilia is associated with abnormally high number of eosinphil granulocytes in the serum and/or tissue
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| * Reference range: '''0-450 ul'''
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| == Differential Diagnosis of Causes of {{PAGENAME}} == | | ==[[Eosinophilia overview|Overview]]== |
| ===By Organ System===
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| {|height:100px" border="1"
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| |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
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| |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Endomyocardial fibrosis]], [[Cholesterol embolism]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Chemical / poisoning'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Dermatologic'''
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| |bgcolor="Beige"| [[Erythema multiforme]], [[Atopic dermatitis]], [[Dermatitis herpetiformis]], [[fasciitis|Eosinophilic fasciitis]], [[folliculitis|Eosinophilic pustular folliculitis]], [[Pemphigus vulgaris]], [[Psoriasis]], [[Systemic lupus erythematosus]], [[Scabies|Sarcoptes scabiei]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Drug Side Effect'''
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| |bgcolor="Beige"| [[Sulphonamides]], [[Allopurinol]], [[Amitriptyline]], [[Capreomycin]], [[Caspofungin]], [[Chlorpropamide]], [[Clomipramine]], [[Daptomycin]], [[Desipramine]], [[Dothiepin]], [[Doxycycline]], [[Enfuvirtide]], [[Etravirine]], [[Gold salts]], [[Granulocyte-macrophage colony stimulating factor]], [[Hydralazine]], [[Imipramine]], [[Interleukin 2]], [[Micafungin]], [[Minocycline]], [[Nalidixic acid]], [[Nitrofurantoin]], [[Nortriptyline]], [[Olanzapine]], [[Oxytetracycline]], [[Pentostatin]], [[Procarbazine]], [[Smoking|Tobacco smoking]], [[Tryptophan]], [[Vancomycin]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Ear Nose Throat'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Endocrine'''
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| |bgcolor="Beige"| [[Adrenal cortex insufficiency]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Environmental'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Gastroenterologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Genetic'''
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| |bgcolor="Beige"| [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 1]], [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 2]], [[Familial eosinophilia]], [[Kostmann disease]], [[Omenn syndrome]], [[Wiskott-Aldrich syndrome]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Hematologic'''
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| |bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Iatrogenic'''
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| |bgcolor="Beige"| [[Radiotherapy]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Infectious Disease'''
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| |bgcolor="Beige"| [[Acanthocheilonemiasis]], [[Alveolar hydatid disease]], [[Ancylostoma caninum]], [[Ancylostoma duodenale]], [[Angiostrongyliasis]], [[Anisakiasis]], [[Ascariasis]], [[Capillaria]], [[Clonorchiasis]], [[Coccidioidomycosis]], [[Dicrocoelium dendriticum fluke]], [[Dracunculiasis]], [[Echinococcus granulosus]], [[Fasciola hepatica]], [[Gnathostomiasis]], [[Heterophyiasis]], [[Lepromatous leprosy]], [[Loa loa filariasis]], [[Lymphatic filariasis]], [[Mansonelliasis]], [[Metagonimiasis]], [[Mycobacterium tuberculosis]], [[Onchocerciasis]], [[Opisthorchiasis]], [[Paragonimiasis]], [[Schistosoma haematobium]], [[Schistosoma mansoni]], [[Strongyloidiasis]], [[Toxocariasis]], [[Trichinella spiralis]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Musculoskeletal / Ortho'''
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| |bgcolor="Beige"| [[Polyarteritis nodosa]], [[Polymyositis]], [[Rheumatoid disease]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Neurologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Nutritional / Metabolic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Obstetric/Gynecologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Oncologic'''
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| |bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Opthalmologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Overdose / Toxicity'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Psychiatric'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Pulmonary'''
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| |bgcolor="Beige"| [[Simple pulmonary eosinophilia]], [[Visceral larva migrans]], [[Allergic bronchopulmonary aspergillosis]], [[Extrinsic allergic alveolitis]], [[Tropical pulmonary eosinophilia]], [[Churg-Strauss syndrome]], [[Bronchial asthma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Renal / Electrolyte'''
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| |bgcolor="Beige"| [[Interstitial nephritis]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Rheum / Immune / Allergy'''
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| |bgcolor="Beige"| [[Eosinophilia-myalgia syndrome]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Sexual'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Trauma'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Urologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Miscellaneous'''
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| |bgcolor="Beige"| Angiolymphoid hyperplasia with eosinophilia, [[cellulitis|Eosinophilic cellulitis]], [[Hypereosinophilic syndrome]], [[Kimura disease]]
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| |-
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| |}
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| ===In alphabetical order <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:127-128 ISBN 1591032016 | | ==[[Eosinophilia historical perspective|Historical Perspective]]== |
| </ref>===
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| * [[Addison's Disease]]
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| * Advanced solid [[tumor]]s
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| * After [[splenectomy]]
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| * [[vasculitis|Allergic vasculitis]]
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| * [[Ancylostomiasis]]
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| * Angioneurotic syndrome
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| * Artheroembolic diseases
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| * [[Ascariasis]]
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| * [[Asthma]]
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| * [[Churg-Strauss Syndrome]]
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| * [[Chronic Myelogenous Leukemia]] ([[CML]])
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| * [[Chronic Renal Disease]]
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| * [[Contact dermatitis]]
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| * [[Dermatitis herpetiformis]]
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| * [[Dermatomyositis]]
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| * [[Drug]] exanthema
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| * [[Drug]]s
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| * [[Dysentery]]
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| * [[Echinococcosis]]
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| * Eosinophilic [[gastroenteritis]]
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| * Eosinophilic [[leukemia]]
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| * Eosinophilic pulmonary infiltrate
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| * [[Erythema infectiosum]]
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| * [[Erythema multiforme]]
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| * [[Erythema nodosum]]
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| * [[Exfoliative dermatitis]]
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| * Facial [[granuloma]]
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| * Familial eosinophilia
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| * [[Felty's Syndrome]]
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| * [[endocarditis|Fibroblastic endocarditis]]
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| * [[Filariasis]]
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| * Food [[allergy]]
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| * Generalized [[carcinoma]]
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| * [[Gonorrhea]]
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| * [[Graft versus host disease]]
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| * [[Hay fever]]
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| * [[Henoch-Schonlein Purpura]]
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| * [[Hodgkin's Lymphoma]]
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| * [[Hypereosinophilic Syndrome]]
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| * [[Hypopituitarism]]
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| * [[Ichthyosis]]
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| * [[Leprosy]]
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| * [[Loeffler's Endocarditis]]
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| * Liver damage in cholestasis
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| * [[Mansonelliasis]]
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| * [[Mastocytosis]]
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| * [[Measles]]
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| * Muscular spasms
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| * [[Mycosis fungoides]]
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| * Myeloproliferative disorder
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| * [[Myxedema]]
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| * [[Necrosis]] near [[tumor]]s
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| * [[Neurodermatitis]]
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| * [[Onchocercosis]]
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| * [[Oxyuriasis]]
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| * Ovarial [[carcinoma]]
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| * [[Pemphigus]]
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| * [[Pernicious anemia]]
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| * [[Pityriasis rosea]]
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| * [[Polyarteritis Nodosa]]
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| * [[Polycythemia]]
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| * [[Psoriasis]]
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| * [[Quincke's Edema]]
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| * Radiation disease
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| * [[Regional enteritis]]
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| * [[Rheumatoid Arthritis]]
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| * [[Sarcoidosis]]
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| * [[Scabies]]
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| * [[Scarlet Fever]]
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| * [[Schistosomiasis]]
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| * [[Serum sickness]]
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| * [[Thyrotoxicosis]]
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| * Toxokarosis
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| * [[Trichinosis]]
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| * Tropical pulmonary eosinophilia
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| * [[Tuberculosis]]
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| * [[Ulcerative colitis]]
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| * [[Urticaria]]
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| * [[Vasculitis]]
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| * [[Waterhouse-Friderichsen Syndrome]]
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| == References == | | ==[[Eosinophilia pathophysiology|Pathophysiology]]== |
| {{Reflist|2}}
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| {{WH}}
| | ==[[Eosinophilia causes|Causes]]== |
| {{WS}}
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| | ==[[Eosinophilia differential diagnosis|Differentiating Eosinophilia from other Diseases]]== |
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| | ==[[Eosinophilia epidemiology and demographics|Epidemiology and Demographics]]== |
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| | ==[[Eosinophilia risk factors|Risk Factors]]== |
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| | ==[[Eosinophilia natural history, complications and prognosis|Natural History, Complications and Prognosis]]== |
| | |
| | ==Diagnosis== |
| | [[Eosinophilia history and symptoms|History and Symptoms]] | [[Eosinophilia physical examination|Physical Examination]] | [[Eosinophilia laboratory findings|Laboratory Findings]] | [[Eosinophilia CT|CT]] | [[Eosinophilia other diagnostic studies|Other Diagnostic Studies]] |
| | |
| | ==Treatment== |
| | [[Eosinophilia medical therapy|Medical Therapy]] | [[Eosinophilia surgery|Surgery]] | [[Eosinophilia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Eosinophilia future or investigational therapies|Future or Investigational Therapies]] |
| | |
| | ==Case Studies== |
| | [[Eosinophilia case study one|Case #1]] |
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| | ==Related Chapters== |
| | *[[Leukocytosis]] |
| | *[[Granulocytosis]] |
| | *[[Neutrophilia]] |
| | *[[Monocytosis]] |
| | *[[Lymphocytosis]] |
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| | [[Category:Laboratory Test]] |
| [[Category:Hematology]] | | [[Category:Hematology]] |
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| [[Category:Blood tests]] | | [[Category:Blood tests]] |
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| | [[Category:Overview complete]] |
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