Endometrial hyperplasia natural history, complications and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
*The majority of cases of endometrial | *The majority of cases of endometrial hyperplasia (except complex atypical hyperplasia) resolve spontaneously with time.<ref name="pmid9255033">{{cite journal| author=Terakawa N, Kigawa J, Taketani Y, Yoshikawa H, Yajima A, Noda K et al.| title=The behavior of endometrial hyperplasia: a prospective study. Endometrial Hyperplasia Study Group. | journal=J Obstet Gynaecol Res | year= 1997 | volume= 23 | issue= 3 | pages= 223-30 | pmid=9255033 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9255033 }} </ref> | ||
*If left untreated, 30% of patients with atypical hyperplasia may progress to develop [[endometrial carcinoma]].<ref name="pmid19285814">{{cite journal| author=Lacey JV, Chia VM| title=Endometrial hyperplasia and the risk of progression to carcinoma. | journal=Maturitas | year= 2009 | volume= 63 | issue= 1 | pages= 39-44 | pmid=19285814 | doi=10.1016/j.maturitas.2009.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19285814 }} </ref> | *If left untreated, 30% of patients with atypical hyperplasia may progress to develop [[endometrial carcinoma]].<ref name="pmid19285814">{{cite journal| author=Lacey JV, Chia VM| title=Endometrial hyperplasia and the risk of progression to carcinoma. | journal=Maturitas | year= 2009 | volume= 63 | issue= 1 | pages= 39-44 | pmid=19285814 | doi=10.1016/j.maturitas.2009.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19285814 }} </ref> | ||
Revision as of 17:42, 28 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
The majority of cases of endometrial hyperplasia (except complex atypical hyperplasia) resolve spontaneously with time.[1] If left untreated, 30% of patients with atypical hyperplasia may progress to develop endometrial carcinoma.[2] Malignant transformation into endometrial cancer is the most common complication of endometrial hyperpasia.[3] Prognosis is generally good with treatment.
Natural History
- The majority of cases of endometrial hyperplasia (except complex atypical hyperplasia) resolve spontaneously with time.[1]
- If left untreated, 30% of patients with atypical hyperplasia may progress to develop endometrial carcinoma.[2]
Complications
Malignant transformation is the most common complication of endometrial hyperpasia.[3]
Prognosis
Prognosis is generally good with treatment for endometrial hyperplasias without atypia.
References
- ↑ 1.0 1.1 Terakawa N, Kigawa J, Taketani Y, Yoshikawa H, Yajima A, Noda K; et al. (1997). "The behavior of endometrial hyperplasia: a prospective study. Endometrial Hyperplasia Study Group". J Obstet Gynaecol Res. 23 (3): 223–30. PMID 9255033.
- ↑ 2.0 2.1 Lacey JV, Chia VM (2009). "Endometrial hyperplasia and the risk of progression to carcinoma". Maturitas. 63 (1): 39–44. doi:10.1016/j.maturitas.2009.02.005. PMID 19285814.
- ↑ 3.0 3.1 Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 16, 2016