Endometrial hyperplasia differential diagnosis: Difference between revisions

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==Overview==
==Overview==
Endometrial hyperplasia must be differentiated from


==Differential Diagnosis==
==Differential Diagnosis==
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===Non-pregnancy related===
===Non-pregnancy related===
*Endometrial carcinoma (variable appearance)
*Endometrial carcinoma (variable appearance)
*Polycystic ovaries (usually uniformly hyperechoic and tends to be diffuse)
*Polycystic ovarian disease (usually uniformly hyperechoic and tends to be diffuse)
*Endometrial polyp or polyps (usually hyperechoic, often focal, look for vascular stalk)
*Endometrial polyp or polyps (usually hyperechoic, often focal, look for vascular stalk)
*Tamoxifen related endometrial changes (variable appearances)
*Tamoxifen related endometrial changes (variable appearances)
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*Submucosal uterine fibroids
*Submucosal uterine fibroids
*Intrauterine adhesions (irregular echogenic areas with focal thickening)
*Intrauterine adhesions (irregular echogenic areas with focal thickening)
*Ovarian tumours associated with endometrial thickening
*Estrogen secreting ovarian tumours
**Endometrioid carcinoma of the ovary
**Granulosa cell ovarian cancer
**Granulosa cell ovarian cancer



Revision as of 16:31, 3 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

Endometrial hyperplasia must be differentiated from

Differential Diagnosis

  • Endometrial hyperplasia must be differentiated from the following:[1]

Pregnancy related

  • Early pregnancy prior to sac being visualized (<5 weeks of gestation)
  • Ectopic pregnancy (thickened endometrium and sometimes fluid collection or pseudogestational sac can be associated)
  • Retained products of conception (heterogeneously thickened endometrium with increased vascularity)
  • Adherent intra-uterine blood clot (heterogeneous endometrium with no vascularity)
  • Molar pregnancy thickened with multiple small cystic spaces
  • Endometritis (prominent hyperechoic endometrium with of without fluid and debris)

Non-pregnancy related

  • Endometrial carcinoma (variable appearance)
  • Polycystic ovarian disease (usually uniformly hyperechoic and tends to be diffuse)
  • Endometrial polyp or polyps (usually hyperechoic, often focal, look for vascular stalk)
  • Tamoxifen related endometrial changes (variable appearances)
  • Hormone replacement therapy (HRT) in postmenopausal female
  • Submucosal uterine fibroids
  • Intrauterine adhesions (irregular echogenic areas with focal thickening)
  • Estrogen secreting ovarian tumours
    • Granulosa cell ovarian cancer

References

  1. Hulka CA, Hall DA, McCarthy K, Simeone JF (1994). "Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography". Radiology. 191 (3): 755–8. doi:10.1148/radiology.191.3.8184058. PMID 8184058.

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