Encephalitis (patient information)

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Encephalitis

Overview

What are the symptoms?

What are the causes?

When to seek urgent medical care?

Diagnosis

Treatment options

Where to find medical care for Encephalitis?

What to expect (Outlook/Prognosis)?

Possible complications

Encephalitis On the Web

Ongoing Trials at Clinical Trials.gov

Images of Encephalitis

Videos on Encephalitis

FDA on Encephalitis

CDC on Encephalitis

Encephalitis in the news

Blogs on Encephalitis

Directions to Hospitals Treating Encephalitis

Risk calculators and risk factors for Encephalitis

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S.

Overview

Encephalitis is irritation and swelling (inflammation) of the brain, most often due to infections.

What are the symptoms of Encephalitis?

Some patients may have symptoms of a cold or stomach infection before encephalitis symptoms begin.

When a case of encephalitis is not very severe, the symptoms may be similar to those of other illnesses, including:

  • Fever that is not very high
  • Mild headache
  • Low energy and a poor appetite

Other symptoms include:

  • Clumsiness, unsteady gait
  • Confusion, disorientation
  • Drowsiness
  • Irritability or poor temper control
  • Light sensitivity
  • Stiff neck and back (occasionally)
  • Vomiting

Symptoms in newborns and younger infants may not be as easy to recognize:

  • Body stiffness
  • Irritability and crying more often (these symptoms may get worse when the baby is picked up)
  • Poor feeding
  • Soft spot on the top of the head may bulge out more
  • Vomiting

Emergency symptoms:

  • Loss of consciousness, poor responsiveness, stupor, coma
  • Muscle weakness or paralysis
  • Seizures
  • Severe headache
  • Sudden change in mental functions:
    • "Flat" mood, lack of mood, or mood that is inappropriate for the situation
    • Impaired judgment
    • Inflexibility, extreme self-centeredness, inability to make a decision, or withdrawal from social interaction
    • Less interest in daily activities
    • Memory loss (amnesia), impaired short-term or long-term memory

What causes Encephalitis?

Encephalitis is a rare condition. It occurs more often in the first year of life and decreases with age. The very young and the elderly are more likely to have a severe case.

Encephalitis is most often caused by a viral infection. Many types of viruses may cause it. Exposure to viruses can occur through:

  • Breathing in respiratory droplets from an infected person
  • Contaminated food or drink
  • Mosquito, tick, and other insect bites
  • Skin contact

Different viruses will occur in different locations. Many cases will tend to cluster in a certain season.

Encephalitis caused by the herpes simplex virus is the leading cause of more severe cases in all ages, including newborns.

A number of viruses for which there is now a vaccine may also cause encephalitis. These include:

  • Measles
  • Mumps
  • Polio
  • Rabies
  • Rubella
  • Varicella (chickenpox)

Other viruses that cause encephalitis include:

  • Adenovirus
  • Coxsackievirus
  • Cytomegalovirus
  • Eastern Equine Encephalitis Virus
  • Echovirus
  • West Nile virus

The virus causes inflammation of brain tissue. The brain tissue swells (cerebral edema), which may destroy nerve cells, cause bleeding in the brain (intracerebral hemorrhage), and brain damage.

When to seek urgent medical care?

Go to the emergency room or call the local emergency number (such as 911) if you have:

Sudden fever Other symptoms of encephalitis

Diagnosis

An examination may show:

  • Abnormal reflexes
  • Increased intracranial pressure
  • Mental confusion
  • Mouth ulcers
  • Muscle weakness
  • Neck stiffness
  • Signs in other organs, such as the liver and lungs
  • Skin rash
  • Speech problems
  • Tests may include:

Brain MRI CT scan of the head Culture of cerebrospinal fluid (CSF), blood, or urine (however, this test is rarely useful) Electroencephalogram (EEG) Lumbar puncture and CSF examination Tests that detect antibodies to a virus (serology tests) Test that detects tiny amounts of virus DNA (polymerase chain reaction -- PCR)

Treatment options

Diseases with similar symptoms

Where to find medical care for Encephalitis?

Directions to Hospitals Treating Condition

What to expect (Outlook/Prognosis)?

Possible complications

Sources

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