Ebola medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2]

Overview

The treatment of Ebola infection is primarily supportive and includes maintaining fluids and electrolytes, homeostasis, adequate oxygen levels and blood pressure and treating any complicating superimposed infections.[1] All patients with a confirmed or suspected viral hemorrhagic fever should be put in isolation with adequate contact precautions.[2] No vaccine is currently available.

Medical Therapy

Treatment for Ebola is primarily supportive. There are no targeted antiviral therapies currently in use.

Bleeding

Replete coagulation factors with fresh frozen plasma if available, and transfuse with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding.

Dehydration

Replete with intravenous fluids that include electrolyte repletion.

Shock

Treat with a combination of intravenous fluids, vasopressors, and blood products as needed.

Hypoxia

Treat with supplemental oxygen including intubation if deemed necessary.

Superimposed Infections

Treating any complicating infections with empiric antibiotics.

References

  1. "CDC Ebola Hemorrhagic Fever Information Packet" (PDF). April 2010.
  2. Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.


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