Ebola medical therapy: Difference between revisions

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==Overview==
==Overview==


The treatment of Ebola infection is primarily supportive and includes maintaining [[fluids]] and [[electrolytes]], [[homeostasis]], adequate [[oxygen]] levels and [[blood pressure]] and treating any complicating superimposed infections.<ref name=CDC>{{cite web | title = CDC Ebola Hemorrhagic Fever Information Packet  | url = http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf | year = April 2010 }}</ref> All patients with a confirmed or suspected viral hemorrhagic fever should be put in isolation with adequate contact precautions.<ref name="pmid21084112">{{cite journal| author=Feldmann H, Geisbert TW| title=Ebola haemorrhagic fever. | journal=Lancet | year= 2011 | volume= 377 | issue= 9768 | pages= 849-62 | pmid=21084112 | doi=10.1016/S0140-6736(10)60667-8 | pmc=PMC3406178 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21084112  }} </ref> No vaccine is currently available.
The treatment of Ebola infection is primarily supportive and includes maintaining [[fluids]] and [[electrolytes]], [[homeostasis]], adequate [[oxygen]] levels and [[blood pressure]] and treating any complicating superimposed [[infections]].<ref name=CDC>{{cite web | title = CDC Ebola Hemorrhagic Fever Information Packet  | url = http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf | year = April 2010 }}</ref> All patients with a confirmed or suspected [[viral hemorrhagic fever]] should be put in isolation with adequate contact precautions.<ref name="pmid21084112">{{cite journal| author=Feldmann H, Geisbert TW| title=Ebola haemorrhagic fever. | journal=Lancet | year= 2011 | volume= 377 | issue= 9768 | pages= 849-62 | pmid=21084112 | doi=10.1016/S0140-6736(10)60667-8 | pmc=PMC3406178 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21084112  }} </ref> No vaccine is currently available.


==Medical Therapy==
==Medical Therapy==

Revision as of 16:08, 16 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2]

Overview

The treatment of Ebola infection is primarily supportive and includes maintaining fluids and electrolytes, homeostasis, adequate oxygen levels and blood pressure and treating any complicating superimposed infections.[1] All patients with a confirmed or suspected viral hemorrhagic fever should be put in isolation with adequate contact precautions.[2] No vaccine is currently available.

Medical Therapy

Treatment is primarily supportive.

Shock

The appropriate treatment of shock depends upon the underlying cause.

Bleeding

Replete coagulation factors with fresh frozen plasma if available, and transfuse with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding.

Dehydration

Replete with intravenous fluids that include electrolyte repletion

Vasodilation

Treat with vasopressors

Hypoxia

Treat with supplemental oxygen including intubation as needed.

Superimposed Infections

Treating any complicating infections with empiric antibiotics.

References

  1. "CDC Ebola Hemorrhagic Fever Information Packet" (PDF). April 2010.
  2. Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.


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