Ebola classification: Difference between revisions
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==Overview== | ==Overview== | ||
Ebola virus can be classified into 5 subtypes: ''Zaïre'', ''Sudan'', ''Reston'', ''Tai (Ivory Coast)'' and ''Bundibugyo''. | Ebola virus can be classified into 5 subtypes: ''Zaïre'', ''Sudan'', ''Reston'', ''Tai (Ivory Coast)'' and ''Bundibugyo'', according to the place of discovery. | ||
==Classification== | |||
The table below summarizes the [[ebola virus]] [[strains]] identified until now: | The table below summarizes the [[ebola virus]] [[strains]] identified until now: | ||
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=====''Zaïre Ebolavirus''===== | =====''Zaïre Ebolavirus''===== | ||
*Among the five [[strains]], ''Zaïre Ebolavirus'' carries the highest [[mortality rate]]. | *Among the five [[strains]], ''Zaïre Ebolavirus'' carries the highest [[mortality rate]]. | ||
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:*It is found in the Democratic Republic of the Congo, Gabon, or the Republic of the Congo. | :*It is found in the Democratic Republic of the Congo, Gabon, or the Republic of the Congo. | ||
:*It has a [[genome]] with two or three [[gene]] overlaps (''VP35''/''VP40'', ''GP''/''VP30'', ''VP24''/''L''). | :*It has a [[genome]] with two or three [[gene]] overlaps (''VP35''/''VP40'', ''GP''/''VP30'', ''VP24''/''L''). | ||
:*It has a [[genomic sequence]] that differs from the | :*It has a [[genomic sequence]] that differs from the [[virus]] type by less than 30%. | ||
=====''Sudan Ebolavirus''===== | =====''Sudan Ebolavirus''===== | ||
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*A [[virus]] of the [[genus]] ''[[Ebolavirus]]'' is considered member of the [[species]] ''Tai Forest ebolavirus'' if:<ref name="KuhnBecker2010">{{cite journal|last1=Kuhn|first1=Jens H.|last2=Becker|first2=Stephan|last3=Ebihara|first3=Hideki|last4=Geisbert|first4=Thomas W.|last5=Johnson|first5=Karl M.|last6=Kawaoka|first6=Yoshihiro|last7=Lipkin|first7=W. Ian|last8=Negredo|first8=Ana I.|last9=Netesov|first9=Sergey V.|last10=Nichol|first10=Stuart T.|last11=Palacios|first11=Gustavo|last12=Peters|first12=Clarence J.|last13=Tenorio|first13=Antonio|last14=Volchkov|first14=Viktor E.|last15=Jahrling|first15=Peter B.|title=Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations|journal=Archives of Virology|volume=155|issue=12|year=2010|pages=2083–2103|issn=0304-8608|doi=10.1007/s00705-010-0814-x}}</ref> | *A [[virus]] of the [[genus]] ''[[Ebolavirus]]'' is considered member of the [[species]] ''Tai Forest ebolavirus'' if:<ref name="KuhnBecker2010">{{cite journal|last1=Kuhn|first1=Jens H.|last2=Becker|first2=Stephan|last3=Ebihara|first3=Hideki|last4=Geisbert|first4=Thomas W.|last5=Johnson|first5=Karl M.|last6=Kawaoka|first6=Yoshihiro|last7=Lipkin|first7=W. Ian|last8=Negredo|first8=Ana I.|last9=Netesov|first9=Sergey V.|last10=Nichol|first10=Stuart T.|last11=Palacios|first11=Gustavo|last12=Peters|first12=Clarence J.|last13=Tenorio|first13=Antonio|last14=Volchkov|first14=Viktor E.|last15=Jahrling|first15=Peter B.|title=Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations|journal=Archives of Virology|volume=155|issue=12|year=2010|pages=2083–2103|issn=0304-8608|doi=10.1007/s00705-010-0814-x}}</ref> | ||
:*It is [[endemic]] in Côte d'Ivoire. | :*It is [[endemic]] in Côte d'Ivoire. | ||
:*It has a [[genome]] with three [[gene]] overlaps ('' | :*It has a [[genome]] with three [[gene]] overlaps (''VP35''/''VP40'', ''GP''/''VP30'', ''VP24''/''L''). | ||
:*It has a [[genomic]] sequence different from ''[[Ebola virus]]'' by ≥30% but different from that of Tai Forest [[virus]] by <30%. | :*It has a [[genomic]] sequence different from ''[[Ebola virus]]'' by ≥30% but different from that of Tai Forest [[virus]] by <30%. | ||
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[[Category:Hemorrhagic fevers]] | [[Category:Hemorrhagic fevers]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
Latest revision as of 17:37, 18 September 2017
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Ebola Microchapters |
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Diagnosis |
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Treatment |
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Postmortem Care |
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Case Studies |
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Ebola classification On the Web |
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American Roentgen Ray Society Images of Ebola classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2]; João André Alves Silva, M.D. [3]
Overview
Ebola virus can be classified into 5 subtypes: Zaïre, Sudan, Reston, Tai (Ivory Coast) and Bundibugyo, according to the place of discovery.
Classification
The table below summarizes the ebola virus strains identified until now:
| Ebola Virus Strain | Place of Discovery | Date Identified |
|---|---|---|
| Sudan ebolavirus | Nzara and Maridi, Sudan | Between June and November 1976 |
| Zaire ebolavirus | Yambuku, Democratic Republic of the Congo | Between August and November 1976 |
| Reston ebolavirus | Reston, Virginia, US. | November 1989 |
| Ivory Coast ebolavirus | Tai Forest, Ivory Coast. | November 1994 |
| Bundibugyo ebolavirus | Bundibugyo District, Uganda | November 2007 |
Zaïre Ebolavirus
- Among the five strains, Zaïre Ebolavirus carries the highest mortality rate.
- A virus of the genus Ebolavirus is considered member of the species Zaire ebolavirus if:[1]
- It is found in the Democratic Republic of the Congo, Gabon, or the Republic of the Congo.
- It has a genome with two or three gene overlaps (VP35/VP40, GP/VP30, VP24/L).
- It has a genomic sequence that differs from the virus type by less than 30%.
Sudan Ebolavirus
- A virus of the genus Ebolavirus is considered member of the species Sudan ebolavirus if:[1]
Reston Ebolavirus
- A virus of the genus Ebolavirus is considered member of the species Reston ebolavirus if:[1]
- If its genome diverges from that of the prototype Reston virus, the Reston virus variant Pennsylvania, by ≤10% at the nucleotide level.
Tai (Ivory Coast) Ebolavirus
- A virus of the genus Ebolavirus is considered member of the species Tai Forest ebolavirus if:[1]
Bundibugyo Ebolavirus
- A virus of the genus Ebolavirus is considered member of the species Bundibugyo ebolavirus if:[1]
- It is endemic in Uganda.
- It has a genome with three gene overlaps (VP35/VP40, GP/VP30, VP24/L).
- It has a genomic sequence different from Ebola virus by ≥30%, but different from that of Bundibugyo virus by <30%.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Kuhn, Jens H.; Becker, Stephan; Ebihara, Hideki; Geisbert, Thomas W.; Johnson, Karl M.; Kawaoka, Yoshihiro; Lipkin, W. Ian; Negredo, Ana I.; Netesov, Sergey V.; Nichol, Stuart T.; Palacios, Gustavo; Peters, Clarence J.; Tenorio, Antonio; Volchkov, Viktor E.; Jahrling, Peter B. (2010). "Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations". Archives of Virology. 155 (12): 2083–2103. doi:10.1007/s00705-010-0814-x. ISSN 0304-8608.