ERF (gene): Difference between revisions

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{{DISPLAYTITLE:''ERF'' (gene)}}
{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''ETS domain-containing transcription factor ERF''' is a [[protein]] that in humans is encoded by the ''ERF'' [[gene]].<ref name="pmid7588608">{{cite journal | vauthors = Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ | title = ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation | journal = The EMBO Journal | volume = 14 | issue = 19 | pages = 4781–93 | date = October 1995 | pmid = 7588608 | pmc = 394576 | doi =  }}</ref><ref name="pmid9192842">{{cite journal | vauthors = de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE | title = Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF) | journal = Genomics | volume = 42 | issue = 2 | pages = 227–35 | date = June 1997 | pmid = 9192842 | pmc =  | doi = 10.1006/geno.1997.4730 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ERF Ets2 repressor factor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2077| accessdate = }}</ref>
| require_manual_inspection = no
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = Ets2 repressor factor
| HGNCid = 3444
| Symbol = ERF
| AltSymbols =; PE-2
| OMIM = 
| ECnumber = 
| Homologene = 68516
| MGIid = 109637
| GeneAtlas_image1 = PBB_GE_ERF_203643_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003706 |text = ligand-regulated transcription factor activity}} {{GNF_GO|id=GO:0003714 |text = transcription corepressor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2077
    | Hs_Ensembl = ENSG00000105722
    | Hs_RefseqProtein = NP_006485
    | Hs_RefseqmRNA = NM_006494
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 47443561
    | Hs_GenLoc_end = 47451113
    | Hs_Uniprot = P50548
    | Mm_EntrezGene = 13875
    | Mm_Ensembl = ENSMUSG00000040857
    | Mm_RefseqmRNA = XM_990042
    | Mm_RefseqProtein = XP_995136
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 24951314
    | Mm_GenLoc_end = 24959425
    | Mm_Uniprot = Q3TXK4
  }}
}}
'''Ets2 repressor factor''', also known as '''ERF''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ERF Ets2 repressor factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2077| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Liu D, Pavlopoulos E, Modi W, Moschonas N, Mavrothalassitis G | title = ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes | journal = Oncogene | volume = 14 | issue = 12 | pages = 1445–51 | date = March 1997 | pmid = 9136988 | doi = 10.1038/sj.onc.1200965 }}
| citations =
* {{cite journal | vauthors = Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G | title = Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation | journal = Molecular and Cellular Biology | volume = 19 | issue = 6 | pages = 4121–33 | date = June 1999 | pmid = 10330152 | pmc = 104371 | doi =  }}
*{{cite journal  | author=Sgouras DN, Athanasiou MA, Beal GJ, ''et al.'' |title=ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. |journal=EMBO J. |volume=14 |issue= 19 |pages= 4781-93 |year= 1995 |pmid= 7588608 |doi=  }}
* {{cite journal | vauthors = Dintilhac A, Bernués J | title = HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7021–8 | date = March 2002 | pmid = 11748221 | doi = 10.1074/jbc.M108417200 }}
*{{cite journal | author=Liu D, Pavlopoulos E, Modi W, ''et al.'' |title=ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes. |journal=Oncogene |volume=14 |issue= 12 |pages= 1445-51 |year= 1997 |pmid= 9136988 |doi= 10.1038/sj.onc.1200965 }}
* {{cite journal | vauthors = Dubois T, Howell S, Zemlickova E, Aitken A | title = Identification of casein kinase Ialpha interacting protein partners | journal = FEBS Letters | volume = 517 | issue = 1–3 | pages = 167–71 | date = April 2002 | pmid = 12062430 | doi = 10.1016/S0014-5793(02)02614-5 }}
*{{cite journal | author=de Castro CM, Rabe SM, Langdon SD, ''et al.'' |title=Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF). |journal=Genomics |volume=42 |issue= 2 |pages= 227-35 |year= 1997 |pmid= 9192842 |doi= 10.1006/geno.1997.4730 }}
* {{cite journal | vauthors = Bain M, Mendelson M, Sinclair J | title = Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells | journal = The Journal of General Virology | volume = 84 | issue = Pt 1 | pages = 41–9 | date = January 2003 | pmid = 12533699 | doi = 10.1099/vir.0.18633-0 }}
*{{cite journal  | author=Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G |title=Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation. |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 4121-33 |year= 1999 |pmid= 10330152 |doi=  }}
* {{cite journal | vauthors = Xiao X, Athanasiou M, Sidorov IA, Horikawa I, Cremona G, Blair D, Barret JC, Dimitrov DS | title = Role of Ets/Id proteins for telomerase regulation in human cancer cells | journal = Experimental and Molecular Pathology | volume = 75 | issue = 3 | pages = 238–47 | date = December 2003 | pmid = 14611815 | doi = 10.1016/S0014-4800(03)00092-3 }}
*{{cite journal | author=Dintilhac A, Bernués J |title=HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7021-8 |year= 2002 |pmid= 11748221 |doi= 10.1074/jbc.M108417200 }}
* {{cite journal | vauthors = Wolvetang EJ, Bradfield OM, Hatzistavrou T, Crack PJ, Busciglio J, Kola I, Hertzog PJ | title = Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis | journal = Neurobiology of Disease | volume = 14 | issue = 3 | pages = 349–56 | date = December 2003 | pmid = 14678752 | doi = 10.1016/S0969-9961(03)00107-4 }}
*{{cite journal | author=Dubois T, Howell S, Zemlickova E, Aitken A |title=Identification of casein kinase Ialpha interacting protein partners. |journal=FEBS Lett. |volume=517 |issue= 1-3 |pages= 167-71 |year= 2002 |pmid= 12062430 |doi= }}
* {{cite journal | vauthors = Le Gallic L, Virgilio L, Cohen P, Biteau B, Mavrothalassitis G | title = ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression | journal = Molecular and Cellular Biology | volume = 24 | issue = 3 | pages = 1206–18 | date = February 2004 | pmid = 14729966 | pmc = 321421 | doi = 10.1128/MCB.24.3.1206-1218.2004 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP | title = A probability-based approach for high-throughput protein phosphorylation analysis and site localization | journal = Nature Biotechnology | volume = 24 | issue = 10 | pages = 1285–92 | date = October 2006 | pmid = 16964243 | doi = 10.1038/nbt1240 }}
*{{cite journal | author=Bain M, Mendelson M, Sinclair J |title=Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells. |journal=J. Gen. Virol. |volume=84 |issue= Pt 1 |pages= 41-9 |year= 2003 |pmid= 12533699 |doi= }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Xiao X, Athanasiou M, Sidorov IA, ''et al.'' |title=Role of Ets/Id proteins for telomerase regulation in human cancer cells. |journal=Exp. Mol. Pathol. |volume=75 |issue= 3 |pages= 238-47 |year= 2003 |pmid= 14611815 |doi= }}
* {{cite journal | vauthors = Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK | title = Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS | journal = Cell Cycle | volume = 6 | issue = 13 | pages = 1594–604 | date = July 2007 | pmid = 17525531 | doi = 10.4161/cc.6.13.4336 }}
*{{cite journal | author=Wolvetang EJ, Bradfield OM, Hatzistavrou T, ''et al.'' |title=Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis. |journal=Neurobiol. Dis. |volume=14 |issue= 3 |pages= 349-56 |year= 2004 |pmid= 14678752 |doi= }}
* {{cite journal | vauthors = Verykokakis M, Papadaki C, Vorgia E, Le Gallic L, Mavrothalassitis G | title = The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression | journal = The Journal of Biological Chemistry | volume = 282 | issue = 41 | pages = 30285–94 | date = October 2007 | pmid = 17699159 | doi = 10.1074/jbc.M704428200 }}
*{{cite journal | author=Le Gallic L, Virgilio L, Cohen P, ''et al.'' |title=ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression. |journal=Mol. Cell. Biol. |volume=24 |issue= 3 |pages= 1206-18 |year= 2004 |pmid= 14729966 |doi=  }}
*{{cite journal  | author=Grimwood J, Gordon LA, Olsen A, ''et al.'' |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Hester KD, Verhelle D, Escoubet-Lozach L, ''et al.'' |title=Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS. |journal=Cell Cycle |volume=6 |issue= 13 |pages= 1594-604 |year= 2007 |pmid= 17525531 |doi= }}
*{{cite journal | author=Verykokakis M, Papadaki C, Vorgia E, ''et al.'' |title=The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression. |journal=J. Biol. Chem. |volume=282 |issue= 41 |pages= 30285-94 |year= 2007 |pmid= 17699159 |doi= 10.1074/jbc.M704428200 }}
}}
{{refend}}
{{refend}}


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* {{MeshName|ERF+protein,+human}}
* {{MeshName|ERF+protein,+human}}


{{NLM content}}
{{Transcription factors|g3}}
[[Category:Transcription factors]]


{{gene-19-stub}}
{{gene-19-stub}}
{{NLM content}}
{{Transcription factors}}
[[Category:Transcription factors]]
{{WikiDoc Sources}}

Latest revision as of 10:56, 2 January 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.[1][2][3]

References

  1. ↑ Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ (October 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". The EMBO Journal. 14 (19): 4781–93. PMC 394576. PMID 7588608.
  2. ↑ de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (June 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.
  3. ↑ "Entrez Gene: ERF Ets2 repressor factor".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Retrieved from "https://www.wikidoc.org/index.php?title=ERF_(gene)&oldid=1530034"