ERF (gene): Difference between revisions

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Revision as of 00:35, 31 August 2017

ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.^[1]^[2]^[3]

References

↑ Sgouras DN, Athanasiou MA, Beal GJ Jr, Fisher RJ, Blair DG, Mavrothalassitis GJ (Nov 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". EMBO J. 14 (19): 4781–93. PMC 394576. PMID 7588608.
↑ de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (Sep 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.
↑ "Entrez Gene: ERF Ets2 repressor factor".

Liu D, Pavlopoulos E, Modi W, et al. (1997). "ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes". Oncogene. 14 (12): 1445–51. doi:10.1038/sj.onc.1200965. PMID 9136988.
Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G (1999). "Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation". Mol. Cell. Biol. 19 (6): 4121–33. PMC 104371. PMID 10330152.
Dintilhac A, Bernués J (2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences". J. Biol. Chem. 277 (9): 7021–8. doi:10.1074/jbc.M108417200. PMID 11748221.
Dubois T, Howell S, Zemlickova E, Aitken A (2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Lett. 517 (1–3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bain M, Mendelson M, Sinclair J (2003). "Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells". J. Gen. Virol. 84 (Pt 1): 41–9. doi:10.1099/vir.0.18633-0. PMID 12533699.
Xiao X, Athanasiou M, Sidorov IA, et al. (2003). "Role of Ets/Id proteins for telomerase regulation in human cancer cells". Exp. Mol. Pathol. 75 (3): 238–47. doi:10.1016/S0014-4800(03)00092-3. PMID 14611815.
Wolvetang EJ, Bradfield OM, Hatzistavrou T, et al. (2004). "Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis". Neurobiol. Dis. 14 (3): 349–56. doi:10.1016/S0969-9961(03)00107-4. PMID 14678752.
Le Gallic L, Virgilio L, Cohen P, et al. (2004). "ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression". Mol. Cell. Biol. 24 (3): 1206–18. doi:10.1128/MCB.24.3.1206-1218.2004. PMC 321421. PMID 14729966.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Hester KD, Verhelle D, Escoubet-Lozach L, et al. (2007). "Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS". Cell Cycle. 6 (13): 1594–604. doi:10.4161/cc.6.13.4336. PMID 17525531.
Verykokakis M, Papadaki C, Vorgia E, et al. (2007). "The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression". J. Biol. Chem. 282 (41): 30285–94. doi:10.1074/jbc.M704428200. PMID 17699159.

External links

ERF+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid7588608-1] Sgouras DN, Athanasiou MA, Beal GJ Jr, Fisher RJ, Blair DG, Mavrothalassitis GJ (Nov 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". EMBO J. 14 (19): 4781–93. PMC 394576. PMID 7588608.

[pmid9192842-2] Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (Sep 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.

[entrez-3] "Entrez Gene: ERF Ets2 repressor factor".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Underlinked|date=May 2016}}
-{{PBB_Controls
+{{DISPLAYTITLE:''ERF'' (gene)}}
-| update_page = yes
+{{Infobox_gene}}
-| require_manual_inspection = no
+'''ETS domain-containing transcription factor ERF''' is a [[protein]] that in humans is encoded by the ''ERF'' [[gene]].<ref name="pmid7588608">{{cite journal | vauthors = Sgouras DN, Athanasiou MA, ((Beal GJ Jr)), Fisher RJ, Blair DG, Mavrothalassitis GJ | title = ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation | journal = EMBO J | volume = 14 | issue = 19 | pages = 4781–93 |date=Nov 1995 | pmid = 7588608 | pmc = 394576 | doi =  }}</ref><ref name="pmid9192842">{{cite journal | vauthors = de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE | title = Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF) | journal = Genomics | volume = 42 | issue = 2 | pages = 227–35 |date=Sep 1997 | pmid = 9192842 | pmc =  | doi = 10.1006/geno.1997.4730 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ERF Ets2 repressor factor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2077| accessdate = }}</ref>
-| update_protein_box = yes
-| update_summary = yes
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-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Ets2 repressor factor
- | HGNCid = 3444
- | Symbol = ERF
- | AltSymbols =; PE-2
- | OMIM =
- | ECnumber =
- | Homologene = 68516
- | MGIid = 109637
- | GeneAtlas_image1 = PBB_GE_ERF_203643_at_tn.png
- | Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003706 |text = ligand-regulated transcription factor activity}} {{GNF_GO|id=GO:0003714 |text = transcription corepressor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 2077
-    | Hs_Ensembl = ENSG00000105722
-    | Hs_RefseqProtein = NP_006485
-    | Hs_RefseqmRNA = NM_006494
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 19
-    | Hs_GenLoc_start = 47443561
-    | Hs_GenLoc_end = 47451113
-    | Hs_Uniprot = P50548
-    | Mm_EntrezGene = 13875
-    | Mm_Ensembl = ENSMUSG00000040857
-    | Mm_RefseqmRNA = XM_990042
-    | Mm_RefseqProtein = XP_995136
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 24951314
-    | Mm_GenLoc_end = 24959425
-    | Mm_Uniprot = Q3TXK4
-  }}
-}}
-'''Ets2 repressor factor''', also known as '''ERF''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ERF Ets2 repressor factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2077| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 55: / Line 11: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Sgouras DN, Athanasiou MA, Beal GJ, ''et al.'' |title=ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. |journal=EMBO J. |volume=14 |issue= 19 |pages= 4781-93 |year= 1995 |pmid= 7588608 |doi=  }}
+*{{cite journal  | vauthors=Liu D, Pavlopoulos E, Modi W |title=ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes. |journal=Oncogene |volume=14 |issue= 12 |pages= 1445–51 |year= 1997 |pmid= 9136988 |doi= 10.1038/sj.onc.1200965 |display-authors=etal}}
-*{{cite journal  | author=Liu D, Pavlopoulos E, Modi W, ''et al.'' |title=ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes. |journal=Oncogene |volume=14 |issue= 12 |pages= 1445-51 |year= 1997 |pmid= 9136988 |doi= 10.1038/sj.onc.1200965 }}
+*{{cite journal  | vauthors=Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G |title=Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation. |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 4121–33 |year= 1999 |pmid= 10330152 |doi=  | pmc=104371  }}
-*{{cite journal  | author=de Castro CM, Rabe SM, Langdon SD, ''et al.'' |title=Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF). |journal=Genomics |volume=42 |issue= 2 |pages= 227-35 |year= 1997 |pmid= 9192842 |doi= 10.1006/geno.1997.4730 }}
+*{{cite journal  | vauthors=Dintilhac A, Bernués J |title=HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7021–8 |year= 2002 |pmid= 11748221 |doi= 10.1074/jbc.M108417200 }}
-*{{cite journal  | author=Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G |title=Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation. |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 4121-33 |year= 1999 |pmid= 10330152 |doi=  }}
+*{{cite journal  | vauthors=Dubois T, Howell S, Zemlickova E, Aitken A |title=Identification of casein kinase Ialpha interacting protein partners. |journal=FEBS Lett. |volume=517 |issue= 1–3 |pages= 167–71 |year= 2002 |pmid= 12062430 |doi=10.1016/S0014-5793(02)02614-5  }}
-*{{cite journal  | author=Dintilhac A, Bernués J |title=HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7021-8 |year= 2002 |pmid= 11748221 |doi= 10.1074/jbc.M108417200 }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Dubois T, Howell S, Zemlickova E, Aitken A |title=Identification of casein kinase Ialpha interacting protein partners. |journal=FEBS Lett. |volume=517 |issue= 1-3 |pages= 167-71 |year= 2002 |pmid= 12062430 |doi=  }}
+*{{cite journal  | vauthors=Bain M, Mendelson M, Sinclair J |title=Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells |journal=J. Gen. Virol. |volume=84 |issue= Pt 1 |pages= 41–9 |year= 2003 |pmid= 12533699 |doi=10.1099/vir.0.18633-0  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Xiao X, Athanasiou M, Sidorov IA |title=Role of Ets/Id proteins for telomerase regulation in human cancer cells |journal=Exp. Mol. Pathol. |volume=75 |issue= 3 |pages= 238–47 |year= 2003 |pmid= 14611815 |doi=10.1016/S0014-4800(03)00092-3  |display-authors=etal}}
-*{{cite journal  | author=Bain M, Mendelson M, Sinclair J |title=Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells. |journal=J. Gen. Virol. |volume=84 |issue= Pt 1 |pages= 41-9 |year= 2003 |pmid= 12533699 |doi=  }}
+*{{cite journal  | vauthors=Wolvetang EJ, Bradfield OM, Hatzistavrou T |title=Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis |journal=Neurobiol. Dis. |volume=14 |issue= 3 |pages= 349–56 |year= 2004 |pmid= 14678752 |doi=10.1016/S0969-9961(03)00107-4  |display-authors=etal}}
-*{{cite journal  | author=Xiao X, Athanasiou M, Sidorov IA, ''et al.'' |title=Role of Ets/Id proteins for telomerase regulation in human cancer cells. |journal=Exp. Mol. Pathol. |volume=75 |issue= 3 |pages= 238-47 |year= 2003 |pmid= 14611815 |doi=  }}
+*{{cite journal  | vauthors=Le Gallic L, Virgilio L, Cohen P |title=ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression |journal=Mol. Cell. Biol. |volume=24 |issue= 3 |pages= 1206–18 |year= 2004 |pmid= 14729966 |doi=10.1128/MCB.24.3.1206-1218.2004  | pmc=321421  |display-authors=etal}}
-*{{cite journal  | author=Wolvetang EJ, Bradfield OM, Hatzistavrou T, ''et al.'' |title=Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis. |journal=Neurobiol. Dis. |volume=14 |issue= 3 |pages= 349-56 |year= 2004 |pmid= 14678752 |doi=  }}
+*{{cite journal  | vauthors=Grimwood J, Gordon LA, Olsen A |title=The DNA sequence and biology of human chromosome 19 |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |display-authors=etal}}
-*{{cite journal  | author=Le Gallic L, Virgilio L, Cohen P, ''et al.'' |title=ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression. |journal=Mol. Cell. Biol. |volume=24 |issue= 3 |pages= 1206-18 |year= 2004 |pmid= 14729966 |doi=  }}
+*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Grimwood J, Gordon LA, Olsen A, ''et al.'' |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
+*{{cite journal  | vauthors=Beausoleil SA, Villén J, Gerber SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
-*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
+*{{cite journal  | vauthors=Hester KD, Verhelle D, Escoubet-Lozach L |title=Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS |journal=Cell Cycle |volume=6 |issue= 13 |pages= 1594–604 |year= 2007 |pmid= 17525531 |doi=10.4161/cc.6.13.4336  |display-authors=etal}}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
+*{{cite journal  | vauthors=Verykokakis M, Papadaki C, Vorgia E |title=The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression |journal=J. Biol. Chem. |volume=282 |issue= 41 |pages= 30285–94 |year= 2007 |pmid= 17699159 |doi= 10.1074/jbc.M704428200 |display-authors=etal}}
-*{{cite journal  | author=Hester KD, Verhelle D, Escoubet-Lozach L, ''et al.'' |title=Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS. |journal=Cell Cycle |volume=6 |issue= 13 |pages= 1594-604 |year= 2007 |pmid= 17525531 |doi=  }}
-*{{cite journal  | author=Verykokakis M, Papadaki C, Vorgia E, ''et al.'' |title=The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression. |journal=J. Biol. Chem. |volume=282 |issue= 41 |pages= 30285-94 |year= 2007 |pmid= 17699159 |doi= 10.1074/jbc.M704428200 }}
 }}
 {{refend}}
@@ Line 82: / Line 37: @@
 == External links ==
 * {{MeshName|ERF+protein,+human}}
+{{NLM content}}
+{{Transcription factors|g3}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+[[Category:Transcription factors]]
 {{gene-19-stub}}
-{{NLM content}}
-{{Transcription factors}}
-[[Category:Transcription factors]]
-{{WikiDoc Sources}}

ERF (gene): Difference between revisions

Revision as of 00:35, 31 August 2017

References

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