Dysfunctional uterine bleeding other diagnostic studies: Difference between revisions

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|+Pathological Imaging
|+Pathological Imaging
!Underlying Cause
!Underlying Cause
!Histological/ Gross PAthology Images
!Histological/ Gross Pathology Images
!Findings
!Findings
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|'''[[Endometrial polyp|Endometrial Polyps]]''' <ref name="“Radiopaedia”">{{cite web|url=https://radiopaedia.org/articles/endometrial-polyp}}</ref>
|'''[[Endometrial polyp|Endometrial Polyps]]''' <ref name="“Radiopaedia”">{{cite web|url=https://radiopaedia.org/articles/endometrial-polyp}}</ref>
|<br />[[File:Endometrial-polyp-with-complex-hyperplasia-and-atypia-pathology.jpg|center|thumb|335x335px|Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259]][[File:Endometrial-polyp-with-complex-hyperplasia-and-atypia-pathology-2.jpg|center|thumb|300x300px|Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259]]
|<br />[[File:Endometrial-polyp-with-complex-hyperplasia-and-atypia-pathology.jpg|center|thumb|335x335px|Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259|alt=]][[File:Endometrial-polyp-with-complex-hyperplasia-and-atypia-pathology-2.jpg|center|thumb|300x300px|Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259|alt=]]




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*vessels with thick walls
*dense fibrous or smooth muscle tissue
*dense fibrous or smooth muscle tissue
*up to 5% may be premalignant or malignant
*up to 5% may be premalignant or malignant
*covered by epithelial tissue<ref name="pmid32491756">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=32491756 | doi= | pmc= | url= }}</ref>
*contain a largely vascular core; vessels with thick walls


<br />
<br />
|-
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|'''[[Adenomyosis]]''' <ref name="“Radiopaedia”2">{{cite web|url=https://radiopaedia.org/articles/adenomyosis}}</ref>
|'''[[Adenomyosis]]''' <ref name="“Radiopaedia”2">{{cite web|url=https://radiopaedia.org/articles/adenomyosis}}</ref>
|<br />[[File:Adenomyosis-histology-1.jpeg|center|thumb|300x300px|Case courtesy of Assoc Prof Frank Gaillard, Radiopaedia.org, rID: 10173]][[File:Adenomyosis-of-the-uterus-gross-pathology-1.jpeg|center|thumb|300x300px|Case courtesy of Ed Uthman, Radiopaedia.org, rID: 10172 ]]<br />
|<br />[[File:Adenomyosis-histology-1.jpeg|center|thumb|300x300px|Case courtesy of Assoc Prof Frank Gaillard, Radiopaedia.org, rID: 10173|alt=]][[File:Adenomyosis-of-the-uterus-gross-pathology-1.jpeg|center|thumb|300x300px|Case courtesy of Ed Uthman, Radiopaedia.org, rID: 10172 |alt=]]<br />
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*ectopic endometrial tissue present within the myometrium
*ectopic endometrial tissue present within the myometrial smooth muscle<ref name="pmid30969690">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=30969690 | doi= | pmc= | url= }}</ref>
|-
|-
|'''[[Leiomyoma]]''' <ref name="“Radiopaedia”3">{{cite web|url=https://radiopaedia.org/articles/uterine-leiomyoma}}</ref>
|'''[[Leiomyoma]]''' <ref name="“Radiopaedia”3">{{cite web|url=https://radiopaedia.org/articles/uterine-leiomyoma}}</ref>
|<br />[[File:Extra-uterine-leiomyomata.jpg|center|thumb|300x300px|Case courtesy of Dr  Hein Els, Radiopaedia.org, rID: 45202]]<br />
|<br />[[File:Extra-uterine-leiomyomata.jpg|center|thumb|300x300px|Case courtesy of Dr  Hein Els, Radiopaedia.org, rID: 45202|alt=]]<br />
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*benign tumours made up of smooth muscle cells with fibrous connective tissue
*benign tumours made up of smooth muscle cells with fibrous connective tissue
*composed of extracellular matrix<ref name="pmid30855861">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=30855861 | doi= | pmc= | url= }}</ref>
*encapsulated with a pseudocapsule
|-
|-
|'''[[Uterine cancer|Malignancy]]''' <ref name="“Radiopaedia”42">{{cite web|url=https://radiopaedia.org/articles/endometrial-carcinoma}}</ref>
|'''[[Uterine cancer|Malignancy]]''' <ref name="“Radiopaedia”42">{{cite web|url=https://radiopaedia.org/articles/endometrial-carcinoma}}</ref>
|<br />[[File:Endometrial carcinoma histo.png|center|thumb|306x306px|PMID: 25969637<ref name="pmid25969637">{{cite journal| author=Faria SC, Sagebiel T, Balachandran A, Devine C, Lal C, Bhosale PR| title=Imaging in endometrial carcinoma. | journal=Indian J Radiol Imaging | year= 2015 | volume= 25 | issue= 2 | pages= 137-47 | pmid=25969637 | doi=10.4103/0971-3026.155857 | pmc=4419423 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25969637  }}</ref>]]
|<br />[[File:Endometrial carcinoma histo.png|center|thumb|306x306px|PMID: 25969637<ref name="pmid25969637">{{cite journal| author=Faria SC, Sagebiel T, Balachandran A, Devine C, Lal C, Bhosale PR| title=Imaging in endometrial carcinoma. | journal=Indian J Radiol Imaging | year= 2015 | volume= 25 | issue= 2 | pages= 137-47 | pmid=25969637 | doi=10.4103/0971-3026.155857 | pmc=4419423 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25969637  }}</ref>|alt=]]





Revision as of 07:28, 14 March 2022



Dysfunctional uterine bleeding Microchapters

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Differentiating Dysfunctional uterine bleeding from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Arooj Naz, Vishnu Vardhan Serla M.B.B.S. [2]

Overview

Other diagnostic studies helpful in detecting the underlying cause include dilatation and curettage to obtain a biopsy. Biopsies can further be studied for their underlying histological findings. hysteroscopy may also be of use in diagnosis.

Other Diagnostic Findings

Other diagnostic findings that may be useful in diagnosis include:


Pathological Imaging
Underlying Cause Histological/ Gross Pathology Images Findings
Endometrial Polyps [1]
Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259
Case courtesy of Dr Mikkaela McCormack, Radiopaedia.org, rID: 44259



  • dense fibrous or smooth muscle tissue
  • up to 5% may be premalignant or malignant
  • covered by epithelial tissue[2]
  • contain a largely vascular core; vessels with thick walls


Adenomyosis [3]
Case courtesy of Assoc Prof Frank Gaillard, Radiopaedia.org, rID: 10173
Case courtesy of Ed Uthman, Radiopaedia.org, rID: 10172

  • ectopic endometrial tissue present within the myometrial smooth muscle[4]
Leiomyoma [5]
Case courtesy of Dr  Hein Els, Radiopaedia.org, rID: 45202

  • benign tumours made up of smooth muscle cells with fibrous connective tissue
  • composed of extracellular matrix[6]
  • encapsulated with a pseudocapsule
Malignancy [7]
PMID: 25969637[8]



  • Type 1: arises due to unopposed hyperestrogenism; the most common histological subtype
  • Type 2: arises due to endometrial atrophy; subtypes include papillary serous, clear cell, squamous and undifferentiated carcinoma

References

  1. https://radiopaedia.org/articles/endometrial-polyp. Missing or empty |title= (help)
  2. "StatPearls".   ( ). 2022:  . PMID 32491756 Check |pmid= value (help).
  3. https://radiopaedia.org/articles/adenomyosis. Missing or empty |title= (help)
  4. "StatPearls".   ( ). 2022:  . PMID 30969690.
  5. https://radiopaedia.org/articles/uterine-leiomyoma. Missing or empty |title= (help)
  6. "StatPearls".   ( ). 2022:  . PMID 30855861.
  7. https://radiopaedia.org/articles/endometrial-carcinoma. Missing or empty |title= (help)
  8. Faria SC, Sagebiel T, Balachandran A, Devine C, Lal C, Bhosale PR (2015). "Imaging in endometrial carcinoma". Indian J Radiol Imaging. 25 (2): 137–47. doi:10.4103/0971-3026.155857. PMC 4419423. PMID 25969637.

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