| No. |
Drug Name |
Active Ingredient |
Approval Date |
FDA-approved use on approval date
|
| 48 |
Ubrelvy |
ubrogepant |
12/23/2019 |
to treat acute treatment of migraine with or without aura in adults
|
| 47 |
Enhertu |
fam-trastuzumab deruxtecan-nxki |
12/20/2019 |
To treat metastatic breast cancer
|
| 46 |
Dayvigo |
lemborexant |
12/20/2019 |
To treat insomnia
|
| 45 |
Caplyta |
lumateperone tosylate |
12/20/2019 |
To treat schizophrenia
|
| 44 |
TissueBlue |
Brilliant Blue G Ophthalmic Solution |
12/20/2019 |
Dye used in eye surgery
|
| 43 |
Padcev |
enfortumab vedotin-ejfv |
12/18/2019 |
To treat refractory bladder cancer
|
| 42 |
Vyondys 53 |
golodirsen |
12/12/2019 |
To treat certain patients with Duchenne muscular dystrophy
|
| 41 |
Oxbryta |
voxelotor |
11/25/2019 |
To treat sickle cell disease
|
| 40 |
Xcopri |
cenobamate |
11/21/2019 |
To treat partial onset seizures
|
| 39 |
Givlaari |
givosiran |
11/20/2019 |
To treat acute hepatic porphyria, a rare blood disorder
|
| 38 |
Adakveo |
crizanlizumab-tmca |
11/15/2019 |
To treat patients with painful complication of sickle cell disease
|
| 37 |
Fetroja |
cefiderocol |
11/14/2019 |
To treat patients with complicated urinary tract infections who have limited or no alternative treatment options
|
| 36 |
Brukinsa |
zanubrutinib |
11/14/2019 |
To treat certain patients with mantle cell lymphoma, a form of blood cancer
|
| 35 |
Reblozyl |
luspatercept–aamt |
11/8/2019 |
For the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell transfusions
|
| 34 |
ExEm Foam |
air polymer-type A |
11/7/2019 |
A diagnostic agent used to assess fallopian tube patency (openness) in women with known or suspected infertility
|
| 33 |
Trikafta |
elexacaftor/ivacaftor/tezacaftor |
10/21/2019 |
To treat patients 12 years of age and older with the most common gene mutation that causes cystic fibrosis
|
| 32 |
Reyvow |
lasmiditan |
10/11/2019 |
For the acute treatment of migraine with or without aura, in adults
|
| 31 |
|
fluorodopa F 18 |
10/10/2019 |
A diagnostic agent for use in positron emission tomography (PET) to help diagnose adult patients with suspected Parkinsonian syndromes (PS)
|
| 30 |
Scenesse |
afamelanotide |
10/8/2019 |
To increase pain-free light exposure in adult patients with a history of phototoxic reactions (damage to skin) from erythropoietic protoporphyria
|
| 29 |
Beovu |
brolucizumab–dbll |
10/7/2019 |
Treatment of wet age-related macular degeneration
|
| 28 |
Aklief |
trifarotene |
10/4/2019 |
For the topical treatment of acne vulgaris in patients 9 years of age and older
|
| 27 |
Ibsrela |
tenapanor |
9/12/2019 |
To treat irritable bowel syndrome with constipation in adults.
|
| 26 |
Nourianz |
istradefylline |
8/27/2019 |
To treat adult patients with Parkinson’s disease experiencing “off” episodes
|
| 25 |
Ga-68-DOTATOC |
Ga-68-DOTATOC |
8/21/2019 |
For use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs)
|
| 24 |
Xenleta |
lefamulin |
8/19/2019 |
To treat adults with community-acquired bacterial pneumonia
|
| 23 |
Rinvoq |
upadacitinib |
8/16/2019 |
To treat adults with moderately to severely active rheumatoid arthritis
|
| 22 |
Inrebic |
fedratinib |
8/16/2019 |
To treat adult patients with intermediate-2 or high-risk primary or secondary myelofibrosis
|
| 21 |
Rozlytrek |
entrectinib |
8/15/2019 |
To treat adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are ROS1-positive
|
| 20 |
Wakix |
pitolisant |
8/14/2019 |
To treat excessive daytime sleepiness (EDS) in adult patients with narcolepsy
|
| 19 |
|
pretomanid |
8/14/2019 |
For treatment-resistant forms of tuberculosis that affects the lungs
|
| 18 |
Turalio |
pexidartinib |
8/2/2019 |
To treat adult patients with symptomatic tenosynovial giant cell tumor
|
| 17 |
Nubeqa |
darolutamide |
7/30/2019 |
To treat adult patients with non-metastatic castration resistant prostate cancer
|
| 16 |
Accrufer |
ferric maltol |
7/25/2019 |
To treat iron deficiency anemia in adults
|
| 15 |
Recarbrio |
imipenem, cilastatin and relebactam |
7/16/2019 |
To treat complicated urinary tract and complicated intra-abdominal infections
|
| 14 |
Xpovio |
selinexor |
7/3/2019 |
To treat adult patients with relapsed or refractory multiple myeloma (RRMM)
|
| 13 |
Vyleesi |
bremelanotide |
6/21/2018 |
To treat hypoactive sexual desire disorder in premenopausal women.
|
| 12 |
Polivy |
polatuzumab vedotin-piiq |
6/10/2019 |
To treat adult patients with relapsed or refractory diffuse large B-cell lymphoma
|
| 11 |
Piqray |
alpelisib |
5/24/2019 |
To treat breast cancer
|
| 10 |
Vyndaqel |
tafamidis meglumine |
5/3/2019 |
To treat heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM) in adults
|
| 9 |
Skyrizi |
risankizumab-rzaa |
4/23/2019 |
To treat moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy
|
| 8 |
Balversa |
erdafitinib |
4/12/2019 |
To treat adult patients with locally advanced or metastatic bladder cancer
|
| 7 |
Evenity |
romosozumab-aqqg |
4/9/2019 |
To treat osteoporosis in postmenopausal women at high risk of fracture
|
| 6 |
Mayzent |
siponimod |
3/26/2019 |
To treat adults with relapsing forms of multiple sclerosis
|
| 5 |
Sunosi |
solriamfetol |
3/20/2019 |
To treat excessive sleepiness in adult patients with narcolepsy or obstructive sleep apnea
|
| 4 |
Zulresso |
brexanolone |
3/19/2019 |
To treat postpartum depression (PPD) in adult women
|
| 3 |
Egaten |
triclabendazole |
2/13/2019 |
To treat fascioliasis, a parasitic infestation caused by two species of flatworms or trematodes that mainly the affect the liver, sometimes referred to as “liver flukes”
|
| 2 |
Cablivi |
caplacizumab-yhdp |
2/6/2019 |
To treat adult patients with acquired thrombotic thrombocytopenic purpura (aTTP)
|
| 1 |
Jeuveau |
prabotulinumtoxinA-xvfs |
2/1/2019 |
For the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients
|