Down syndrome: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
 
(8 intermediate revisions by 3 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
'''For patient information click [[{{PAGENAME}}  (patient information)|here]]'''
{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name          = Down syndrome |
   Name          = Down syndrome |
  ICD10          = {{ICD10|Q|90||q|90}} |
  ICD9          = {{ICD9|758.0}} |
  ICDO          = |
   Image          = Drill.jpg <!--- Do not change this picture without discussing it in the Down syndrome discussion page. Because of continued vandalism, pictures will be immediately reverted. ---> |
   Image          = Drill.jpg <!--- Do not change this picture without discussing it in the Down syndrome discussion page. Because of continued vandalism, pictures will be immediately reverted. ---> |
   Caption        = Boy with Down syndrome assembling a bookcase|
   Caption        = Boy with Down syndrome assembling a bookcase|
  OMIM          = 190685 |
  OMIM_mult      = |
  MedlinePlus    = 000997 |
  DiseasesDB    = 3898 |
  MeshID        = D004314 |
}}
}}
{{Down syndrome}}
{{Down syndrome}}
{{CMG}}
'''For patient information, click [[Down syndrome (patient information)|here]]'''
 
{{CMG}} {{AE}} {{HK}} {{SH}}
 
{{SK}} Trisomy 21, trisomy 21 syndrome, mongolianism, mongolism, Down's syndrome baby


==[[Down syndrome overview|Overview]]==
==[[Down syndrome overview|Overview]]==
Line 37: Line 32:
==Diagnosis==
==Diagnosis==


[[Down syndrome history and symptoms|History and Symptoms]] | [[Down syndrome physical examination|Physical Examination]] | [[Down syndrome laboratory findings|Laboratory Findings]] | [[Down syndrome electrocardiogram|Electrocardiogram]] | [[Down syndrome chest x ray|Chest X Ray]] | [[Down syndrome CT|CT]] | [[Down syndrome MRI|MRI]] | [[Down syndrome echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Down syndrome other imaging findings|Other Imaging Findings]] | [[Down syndrome other diagnostic studies|Other Diagnostic Studies]]
[[Down syndrome history and symptoms|History and Symptoms]] | [[Down syndrome physical examination|Physical Examination]] | [[Down syndrome laboratory findings|Laboratory Findings]] | [[Down syndrome electrocardiogram|Electrocardiogram]] | [[Down syndrome x ray|X Ray]] | [[Down syndrome CT|CT]] | [[Down syndrome MRI|MRI]] | [[Down syndrome echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Down syndrome other imaging findings|Other Imaging Findings]] | [[Down syndrome other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==


[[Down syndrome medical therapy|Medical Therapy]] | [[Down syndrome surgery|Surgery]] | [[Down syndrome primary prevention|Primary Prevention]] | [[Down syndrome cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Down syndrome future or investigational therapies|Future or Investigational Therapies]] | [[Down syndrome sociological and cultural aspects|Sociological and Cultural Aspects]]
[[Down syndrome medical therapy|Medical Therapy]] | [[Down syndrome surgery|Surgery]] | [[Down syndrome primary prevention|Primary Prevention]] | [[Down syndrome secondary prevention|Secondary Prevention]] | [[Down syndrome cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Down syndrome future or investigational therapies|Future or Investigational Therapies]] | [[Down syndrome sociological and cultural aspects|Sociological and Cultural Aspects]]
 
*  
==Sources==
*Arron, Joseph R., et al. (2006). NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. ''Nature, 441'': 595-599.
*Epstein, Charles J. (2006). Critical Genes in Critical Region. ''Nature, 441'': 582-583.
* {{cite book
| last =Ganong
| first =W.J.
| year =2005
| title =Review of Medical Physiology
| publisher =Mc-Graw Hill
| location =New York
}}
*Nelson, David L., & Gibbs, Richard H. (2004). The Critical Region in Trisomy-21. ''Science, 306'': 619-621.
*Olson, L.E., Richtsmeier J.T., & Reeves R.H. (2004). A Chromosome-21 Critical Region Does Not Cause Specific Down Syndrome Phenotypes. ''Science, 306'': 687-690.
*Reeves, Roger H., et al. (2000). The DNA Sequence of Human Chromosome 21. ''Nature, 405'': 311-319.
* {{cite book
| last =Underwood
| first =J.C.E.
| year =2004
| title =General and Systematic Pathology
| publisher =Churchill Livingstone
| location =Edinburgh
}}
 
==Bibliography==
* {{cite book
| last =Beck
| first =M.N.
| year =1999
| title =Expecting Adam
| publisher =Berkley Books
| location =New York
}}
* {{cite book
| last =Buckley
| first =S.
| year =2000
| title =Living with Down Syndrome
| publisher =The Down Syndrome Educational Trust
| location =Portsmouth, UK
| url =http://books.google.com/books?id=__5wB08U2hMC
| isbn =1903806011
}}
* {{cite book
| last =Down Syndrome Research Foundation
| year =2005
| title =Bright Beginnings: A Guide for New Parents
| publisher =Down Syndrome Research Foundation
| location =Buckinghamshire, UK
| url =http://www.dsrf.co.uk/Reading_material/Bright_beginnings.htm
}}
* {{cite journal
| journal= Ment Retard Dev Disabil Res Rev
| year= 2007
| volume= 13
| issue= 3
| pages= 272–8
| title= Psychiatric and behavioral disorders in persons with Down syndrome
| author= Dykens EM
| doi= 10.1002/mrdd.20159
| pmid= 17910080
}}
* Hassold, T.J., D. Patterson, eds. (1999). ''Down Syndrome: A Promising Future, Together''. New York: Wiley Liss.
* {{cite book
| last =Kingsley
| first =J.
| coauthors =M. Levitz
| year =1994
| title =Count Us In: Growing up with Down Syndrome
| publisher =Harcourt Brace
| location =San Diego
}}
* Pueschel, S.M., M. Sustrova, eds. (1997). ''Adolescents with Down Syndrome: Toward a More Fulfilling Life''. Baltimore, MD: Paul H. Brookes.
* {{cite book
| last =Selikowitz
| first =M.
| edition =2nd edition
| year =1997
| title =Down Syndrome: The Facts
| publisher =Oxford University Press
| location =Oxford, UK
}}
* {{cite book
| last =Van Dyke
| first =D.C.
| coauthors =P.J. Mattheis, S. Schoon Eberly, J. Williams
| year =1995
| title =Medical and Surgical Care for Children with Down Syndrome
| publisher =Woodbine House
| location =Bethesda, MD
}}
* {{cite book
| last =Zuckoff
| first =M.
| year =2002
| title =Choosing Naia: A Family's Journey
| publisher =Beacon Press
| location =New York
}}


{{Chromosomal abnormalities}}
{{Chromosomal abnormalities}}

Latest revision as of 13:01, 21 March 2018

Template:DiseaseDisorder infobox

Down syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Down syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Sociological and Cultural Aspects

Case Studies

Case #1

Down syndrome On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Down syndrome

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Down syndrome

CDC on Down syndrome

Down syndrome in the news

Blogs on Down syndrome

Directions to Hospitals Treating Down syndrome

Risk calculators and risk factors for Down syndrome

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2] Dildar Hussain, MBBS [3]

Synonyms and keywords: Trisomy 21, trisomy 21 syndrome, mongolianism, mongolism, Down's syndrome baby

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Down syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies | Sociological and Cultural Aspects

Template:Chromosomal abnormalities


Template:WikiDoc Sources