Donovanosis overview: Difference between revisions
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Donovanosis is a [[sexually transmitted disease]] that has reached [[Endemic (epidemiology)|endemic]] proportions in many underdeveloped regions. Because of the scarcity of medical treatment, the disease often goes untreated. The disease is characterized by '''painless [[genital ulcer]]s''' which can be mistaken for [[syphilis]].<ref>Murray P. et al. (2005), ''Medical Microbiology, fifth ed.'', Elsevier Mosby, p. 336.</ref> However, they ultimately progress to destruction of internal and external tissue, with leakage of [[mucus]] and [[blood]]. The destructive nature of donovanosis also increases the risk of[[superinfection]] by other pathogenic microbes. | Donovanosis is a [[sexually transmitted disease]] that has reached [[Endemic (epidemiology)|endemic]] proportions in many underdeveloped regions. Because of the scarcity of medical treatment, the disease often goes untreated. The disease is characterized by '''painless [[genital ulcer]]s''' which can be mistaken for [[syphilis]].<ref>Murray P. et al. (2005), ''Medical Microbiology, fifth ed.'', Elsevier Mosby, p. 336.</ref> However, they ultimately progress to destruction of internal and external tissue, with leakage of [[mucus]] and [[blood]]. The destructive nature of donovanosis also increases the risk of[[superinfection]] by other pathogenic microbes. | ||
==Causes== | |||
The causative organism, ''[[Klebsiella]] granulomatis'', used to be called ''Calymmatobacterium granulomatis'', from the Greek ''kalymma'' (a hood or veil), referring to the lesions that contain the bacteria. Prior to this it was called ''Donovania granulomatis'', named after the Donovan Bodies.<ref>Murray P. et al. (2005), ''Medical Microbiology, fifth ed.'', Elsevier Mosby, p. 336.</ref> The species name ''granulomatis'' refers to the granulomatous lesions. The organism was recently reclassified under the genus ''Klebsiella'', a drastic taxonomic change, since it involved changing the organism's [[phylum]]. | |||
==Epidemiology and Demographics== | |||
Donovanosis is [[endemic]] in developing countries and mostly affects 20-40 years old men. | |||
==Diagnosis== | |||
===Physical Examination=== | |||
Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional [[lymphadenopathy]]. | |||
==Treatment== | |||
===Prevention=== | |||
Avoiding all sexual activity is the only absolute way to prevent a sexually transmitted disease such as donovanosis. However, safer sex behaviors may reduce your risk. | |||
The proper use of [[condom]]s, either the male or female type, greatly decreases the risk of catching a [[sexually transmitted disease]]. You need to wear the condom from the beginning to the end of each sexual activity. | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 17:06, 5 December 2012
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Donovanosis Microchapters |
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Diagnosis |
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Donovanosis overview On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]
Overview
Donovanosis is a sexually transmitted disease that has reached endemic proportions in many underdeveloped regions. Because of the scarcity of medical treatment, the disease often goes untreated. The disease is characterized by painless genital ulcers which can be mistaken for syphilis.[1] However, they ultimately progress to destruction of internal and external tissue, with leakage of mucus and blood. The destructive nature of donovanosis also increases the risk ofsuperinfection by other pathogenic microbes.
Causes
The causative organism, Klebsiella granulomatis, used to be called Calymmatobacterium granulomatis, from the Greek kalymma (a hood or veil), referring to the lesions that contain the bacteria. Prior to this it was called Donovania granulomatis, named after the Donovan Bodies.[2] The species name granulomatis refers to the granulomatous lesions. The organism was recently reclassified under the genus Klebsiella, a drastic taxonomic change, since it involved changing the organism's phylum.
Epidemiology and Demographics
Donovanosis is endemic in developing countries and mostly affects 20-40 years old men.
Diagnosis
Physical Examination
Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional lymphadenopathy.
Treatment
Prevention
Avoiding all sexual activity is the only absolute way to prevent a sexually transmitted disease such as donovanosis. However, safer sex behaviors may reduce your risk.
The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted disease. You need to wear the condom from the beginning to the end of each sexual activity.