Disseminated intravascular coagulation history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

• The signs and symptoms of DIC are highly variable, and for a large part depend upon the precipitating cause.

  • Common features include:

    • Fever
    • Hypotension
    • Acidosis
    • Proteinuria
    • Hypoxia.

  • Bleeding from wounds or puncture sites is also commonly seen.
  • Patients with low-grade DIC tend to have subacute bleeding and thrombosis, and although most tests of global coagulation are normal, FDPs (flexor digitorum profundus) are uniformly elevated.