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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Disequilibrium}}
{{Disequilibrium}}
{{CMG}}; {{VR}}
{{CMG}}; {{VR}}


{{SK}} Bad balance; chronic dizziness; dizzy; imbalance; instability; loss of balance; off balance; unsteadiness
{{SK}} Bad balance; chronic dizziness; imbalance; instability; loss of balance; off balance; unsteadiness


==Overview==
==[[Disequilibrium overview|Overview]]==
'''Disequilibrium''' refers to an impaired sense or absence of balance or [[equilibrioception]] that primarily occurs during standing or walking usually without any cephalic sensations like headache, nausea and vomiting.  It is one among the causes of [[dizziness]]<ref name="urlChapter 14: Evaluation of the Dizzy Patient">{{cite web |url=http://www.dartmouth.edu/~dons/part_2/chapter_14.html#chpt_14_presyncope |title=Chapter 14: Evaluation of the Dizzy Patient |format= |work= |accessdate=2009-08-06}}</ref>.


==Causes==
==[[Disequilibrium historical perspective|Historical Perspective]]==
===Life Threatening Causes===
*[[Arrhythmia]]
*[[Asthma|Asthma exacerbation]]
*[[Intracranial hemorrhage|Cerebellar hemorrhage]]
*[[Compartment syndrome]]
*[[Endophthalmitis]]
*[[Epilepsy]]
*[[Hypoglycemia]]
*[[Organophosphates]]


===Common Causes===
==[[Disequilibrium classification|Classification]]==
*[[Cerebellar ataxia|Cerebellar disorders]]
*[[Gait abnormality]]
*[[Hypoglycemia]]
*[[Paralysis]]
*[[Peripheral neuropathy]]
*[[Vertigo|Vestibular disorders]]
*[[Visual impairment]]<ref name="Sturnieks-2008">{{Cite journal  | last1 = Sturnieks | first1 = DL. | last2 = St George | first2 = R. | last3 = Lord | first3 = SR. | title = Balance disorders in the elderly. | journal = Neurophysiol Clin | volume = 38 | issue = 6 | pages = 467-78 | month = Dec | year = 2008 | doi = 10.1016/j.neucli.2008.09.001 | PMID = 19026966 }}</ref><ref name="Kroenke-1992">{{Cite journal  | last1 = Kroenke | first1 = K. | last2 = Lucas | first2 = CA. | last3 = Rosenberg | first3 = ML. | last4 = Scherokman | first4 = B. | last5 = Herbers | first5 = JE. | last6 = Wehrle | first6 = PA. | last7 = Boggi | first7 = JO. | title = Causes of persistent dizziness. A prospective study of 100 patients in ambulatory care. | journal = Ann Intern Med | volume = 117 | issue = 11 | pages = 898-904 | month = Dec | year = 1992 | doi =  | PMID = 1443950 }}</ref><ref name="Cherchi-2011">{{Cite journal  | last1 = Cherchi | first1 = M. | title = Infrequent causes of disequilibrium in the adult. | journal = Otolaryngol Clin North Am | volume = 44 | issue = 2 | pages = 405-14, ix | month = Apr | year = 2011 | doi = 10.1016/j.otc.2011.01.011 | PMID = 21474014 }}</ref>


===Causes by Organ System===
==[[Disequilibrium pathophysiology|Pathophysiology]]==
{|style="width:82%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Acute coronary syndrome]],  [[arrhythmia]],  [[arteriosclerosis]],  [[cardiomyopathy]],  [[congestive cardiac failure]],  [[dehydration]],  [[hypertension]],  [[hypotension]],  [[microscopic polyangiitis]],  [[myocardial infarction]],  [[postural hypotension]],  [[transient ischaemic attack]],  [[vasculitis]],  [[vertebral artery dissection]]
|-
|-bgcolor="LightSteelBlue"
| '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Acrylamide]],  [[arsenic]],  [[heavy metals]],  [[konzo]],  [[lead]],  [[mercury]],  [[methanol]],  [[organophosphates]],  [[salicylate poisoning]]
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Aminophylline]],  [[amiodarone]],  [[amphotericin B]],  [[antihypertensives]],  [[antibiotics]],  [[anticholinergics]],  [[anticonvulsants]],  [[antidepressants]],  [[aspirin]],  [[aurothioglucose]],  [[biguanide]],  [[bortezomib]],  [[capecitabine]],  [[carbachol]],  [[carbon tetrachloride]],  [[celecoxib]],  [[chlorpheniramine]],  [[cinnarizine]],  [[cisplatin]],  [[clomifene]],  [[colchicine]],  [[dapsone]],  [[diphenhydramine]],  [[disulfiram]],  [[diuretics]],  [[ethambutol]],  [[ethotoin]],  [[fluorouracil]],  [[hydralazine]],  [[hydroxyzine]],  [[isoniazid]],  [[ixabepilone]],  [[lamivudine]],  [[leflunomide]],  [[linezolid]],  [[lithium]],  [[mefloquine]],  [[melarsoprol]],  [[metronidazole]],  [[nalidixic acid ]],  [[neuroleptics]],  [[nitrofurantoin]],  [[nortriptyline]],  [[nucleoside analogues]],  [[oxaliplatin]],  [[paclitaxel]],  [[phenylbutazone]],  [[phenytoin]],  [[physostigmine]],  [[prochlorperazine]],  [[pyridoxine]],  [[rofecoxib]],  [[sedatives]],  [[stavudine]],  [[suramin]],  [[taxol]],  [[thallium]],  [[toluene]],  [[trabectedin]],  [[tranquilizers]],  [[vaccines]],  [[verteporfin]],  [[vigabatrin]],  [[vincristine]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| [[Hearing impairment|Impaired hearing]]
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| [[Acromegaly]],  [[diabetes mellitus]],  [[diabetic amyotrophy]],  [[diabetic ketoacidosis]],  [[Diabetic neuropathy|diabetic radiculopathy]],  [[hyperthyroidism]],  [[hypoparathyroidism]],  [[hypothyroidism]],  [[phaeochromocytoma]]
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| [[Altitude sickness]],  [[cold exposure]],  [[electrical injury]],  [[heat stroke]],  [[lathyrism]]
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Celiac disease]],  [[chronic liver disease]],  [[hepatic cirrhosis]],  [[Fistula|intestinal fistula]],  [[primary biliary cirrhosis]],  [[pyloric stenosis]],  [[tropical sprue]],  [[viral hepatitis]]
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| [[3-methylglutaconic aciduria]],  [[Leukoencephalopathy|4H syndrome]],  [[abetalipoproteinemia]],  [[adrenoleukodystrophy]],  [[adrenomyeloneuropathy]],  [[alpha-mannosidase deficiency]],  [[AMACR|alpha-methylacyl-CoA racemase deficiency]],  [[argininosuccinic aciduria]],  [[Metachromatic leukodystrophy|arylsulphatase A deficiency]],  [[aspartoacylase deficiency]],  [[ataxia-telangiectasia]],  [[Cutis laxa|ATP6V0A2-related cutis laxa]],  [[bilateral frontoparietal polymicrogyria]],  [[biotinidase deficiency]],  [[carbamoylphosphate synthetase deficiency]],  [[carbohydrate deficient glycoprotein syndrome type 1a]],  [[SACS (gene)|Charlevoix-Saguenay spastic ataxia]],  [[Cockayne syndrome]],  [[Mitochondrial disease|coenzyme Q10 deficiency]],  [[De Grouchy Syndrome]],  [[dentatorubral-pallidoluysian atrophy]],  [[Fabry's disease]],  [[familial alphalipoprotein deficiency]],  [[Friedreich's ataxia]],  [[Hyperkalemic periodic paralysis|Gamstorp-Wohlfart syndrome]],  [[glucose phosphate isomerase deficiency]],  [[GM2 gangliosidosis]],  [[Griscelli syndrome]],  [[Haw river syndrome]],  [[hereditary neuralgic amyotrophy]],  [[Huntington disease]],  [[hypobetalipoproteinemia]],  [[Joubert syndrome]],  [[Loken Senior syndrome]],  [[Marinesco-Sjogren syndrome]],  [[MELAS]],  [[MERRF]],  [[MPV17|MPV17 gene mutation]],  [[Biotinidase deficiency|multiple carboxylase deficiency]],  [[Phenylketonuria|phenylalanine hydroxylase deficiency]],  [[progressive external ophthalmoplegia]],  [[Refsum disease]],  [[Charcot-Marie-Tooth Syndrome|Roussy-Levy disease]],  [[Sandhoff disease]],  [[KCNJ10|SeSAME syndrome]],  [[Silver-Russell dwarfism|Silver syndrome]],  [[SPG20|Troyer syndrome]],  [[Unverricht-Lundborg disease]],  [[Van der Knaap disease]],  [[Von Hippel-Lindau syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| [[Anemia]],  [[glucose phosphate isomerase deficiency]],  [[haemochromatosis]],  [[leukemia]],  [[multiple myeloma]],  [[pernicious anemia]], [[plasmacytoma]],  [[polycythemia vera]],  [[sideroblastic anemia]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| [[Myelopathy|Acute necrotizing myelopathy]],  [[Transverse myelitis|acute viral myelitis]],  [[borrelia burgdorferi]],  [[botulism]],  [[Encephalitis|brainstem encephalitis]],  [[brucellosis]],  [[cerebellar abscess]],  [[chickenpox]],  [[coxsackie A virus]],  [[cysticercosis]],  [[Cytomegalovirus|cytomegalovirus polyradiculopathy]],  [[diphtheria]],  [[encephalomyelitis]],  [[endophthalmitis]],  [[epidural abscess]],  [[epstein-barr virus]],  [[Guillain-Barré syndrome]],  [[herpes simplex]],  [[herpes zoster]],  [[HIV]],  [[leprosy]],  [[lyme disease]],  [[malaria]],  [[meningoencephalitis]],  [[mycoplasma pneumoniae]],  [[ophthalmia neonatorum]],  [[osteomyelitis]],  [[polymyositis]],  [[schistosoma]],  [[septic arthritis]],  [[septicemia]],  [[syphilis]],  [[tick paralysis]],  [[transient synovitis]],  [[treponema pallidum]],  [[tuberculosis]],  [[typhoid fever]],  [[viral hepatitis]]
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| [[Carpal tunnel syndrome]],  [[Charcot-Marie-Tooth Syndrome|Charcot-Marie-Tooth disease]],  [[chondroma]],  [[compartment syndrome]],  [[connective tissue disease]],  [[dermatomyositis]],  [[Duchenne muscular dystrophy]],  [[Ewing's sarcoma]],  [[Neuropathy|femoral neuropathy]],  [[hereditary neuralgic amyotrophy]],  [[Spinal disc herniation|herniated vertebral disc]],  [[Bone fracture|leg fractures]],  [[muscle weakness]],  [[osteoarthritis]],  [[osteochondroma]],  [[osteoma]],  [[osteomyelitis]],  [[osteosarcoma]],  [[Pagets disease]],  [[Neuropathy|peroneal compression at the fibular neck]],  [[Perthes disease]],  [[septic arthritis]],  [[slipped upper femoral epiphysis]],  [[tarsal tunnel syndrome]],  [[transient synovitis]]
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| [[Acoustic neuroma]],  [[Myelopathy|acute necrotizing myelopathy]],  [[Transverse myelitis|acute viral myelitis]],  [[alcoholic polyneuropathy]],  [[amyotrophic lateral sclerosis]],  [[Cerebellar ataxia|anti-glutamic acid decarboxylase associated cerebellar ataxia]],  [[Arnold-Chiari malformation]],  [[Apraxia|ataxia-oculomotor apraxia]],  [[Migraine|basilar migraine]],  [[benign paroxysmal vertigo]],  [[Encephalitis|brainstem encephalitis]],  [[carotid-cavernous fistula]],  [[cerebellar abscess]],  [[cerebellar hypoplasia]],  [[cerebellar ataxia]],  [[Ramsay-Hunt syndrome|cerebellar dyssynergia]], [[Intracranial hemorrhage|cerebellar hemorrhage]],  [[Medulloblastoma|cerebellar tumor]],  [[Dandy-Walker syndrome|cerebellar vermis agenesis]],  [[cerebral palsy]],  [[cerebrotendineous xanthomatosis]],  [[cerebrovascular disease]],  [[ceroid lipofuscinosis]],  [[cervical spondylosis]],  [[cockayne syndrome]],  [[Delirium|confusional state]],  [[Copper deficiency|copper deficiency myeloneuropathy]],  [[cortical visual impairment]],  [[Creutzfeldt-Jakob disease]],  [[Cytomegalovirus|cytomegalovirus polyradiculopathy]],  [[Dandy-Walker syndrome]],  [[Neuropathy|deafferentation]],  [[Myelopathy|decompression sickness myelopathy]],  [[Dejerine Sottas syndrome]],  [[dementia]],  [[demyelination]],  [[diabetic amyotrophy]],  [[Diabetic neuropathy|diabetic radiculopathy]],  [[Schilder's disease|diffuse sclerosis of Schilder]],  [[Hereditary motor and sensory neuropathy|distal hereditary neuronopathy]],  [[dural arteriovenous fistula]],  [[Ramsay-Hunt syndrome|dyssynergia cerebellaris myoclonica]],  [[encephalocele]],  [[encephalomyelitis]],  [[epidural abscess]],  [[epilepsy]],  [[episodic ataxia]],  [[Worster-Drought syndrome|familial Danish dementia]],  [[familial hemiplegic migraine]],  [[Intrauterine growth retardation|fetal akinesia-hypokinesia sequence]],  [[Friedreich's ataxia]],  [[Gerstmann-Sträussler-Scheinker syndrome]],  [[giant axonal neuropathy]],  [[Haw River syndrome]],  [[Familial amyloid polyneuropathy|hereditary amyloid polyneuropathy]],  [[hereditary ataxia]],  [[hereditary sensory and autonomic neuropathy]],  [[hereditary spastic paraplegia]],  [[Spinal disc herniation|Herniated vertebral disc]],  [[hypoxia]],  [[Neuropathy|idiopathic lumbosacral radiculoplexus neuropathy]],  [[Small fiber peripheral neuropathy|idiopathic small fiber neuropathy]],  [[intracranial space-occupying lesion]], [[Kearns-Sayre syndrome]],  [[Klumpke paralysis]],  [[lathyrism]],  [[Leigh syndrome]],  [[Flaccid paralysis|lower motor neuron weakness]],  [[Plexopathy|lumbosacral plexitis]],  [[Machado-Joseph disease]],  [[meningoencephalitis]],  [[meralgia paresthetica]],  [[migraine]],  [[Mitochondrial disease|mitochondrial ataxia]],  [[multifocal motor neuropathy]],  [[multiple lentigines syndrome]],  [[multiple sclerosis]],  [[Neuropathy|multiple sensory defect dizziness]],  [[Shy-Drager syndrome|multiple system atrophy syndromes]],  [[myasthenia gravis]],  [[myelopathy]],  [[Neuropathy, ataxia, and retinitis pigmentosa|NARP  syndrome]],  [[neurofibromatosis]],  [[normal pressure hydrocephalus]],  [[Claude syndrome|Nothnagel Claude syndrome]],  [[Obturator nerve|obturator neuropathy]],  [[olivopontocerebellar atrophy]],  [[Myoclonus|orthostatic myoclonus]],  [[pantothenate kinase]],  [[paraneoplastic cerebellar degeneration]],  [[Neuropathy|paraneoplastic sensory neuropathy]],  [[Parkinson disease]],  [[Pelizaeus-Merzbacher disease]],  [[peripheral neuropathy]],  [[polyrediculitis]],  [[posterior inferior cerebellar artery syndrome]],  [[posterior leucoencephalopathy syndrome]],  [[raised intracranial pressure]],  [[Sandhoff disease]],  [[Neuropathy|sciatic neuropathy]],  [[Arteriovenous malformation|spinal arteriovenous malformations]],  [[spinal cord tumor]],  [[Epidural hematoma|spinal epidural hematoma]],  [[spinocerebellar ataxia]],  [[stroke]],  [[Subacute combined degeneration of spinal cord|subacute combined degeneration]],  [[Leigh's disease|subacute necrotising encephalomyelopathy]],  [[Neuropathy|subacute sensory neuronopathy]],  [[Superior orbital fissure|superior orbital fissure syndrome]],  [[syringobulbia]],  [[syringomyelia]],  [[transient ischaemic attack]],  [[transverse myelitis]],  [[Unverricht-Lundborg disease]],  [[Spasticity|upper motor neuron weakness]],  [[urination]],  [[Van der Knaap disease]],  [[vasculitis]],  [[Vasovagal syncope|vasovagal attacks]],  [[Vertigo|vestibular disorder]]
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[2-hydroxyglutarate dehydrogenase|2-hydroxyglutarate dehydrogenase deficiency]],  [[acute intermittent porphyria]],  [[alpha-mannosidase deficiency]],  [[AMACR|alpha-methylacyl-CoA racemase deficiency]],  [[argininosuccinic aciduria]],  [[Metachromatic leukodystrophy|arylsulphatase A deficiency]],  [[aspartoacylase deficiency]],  [[beri-beri]],  [[carbamoylphosphate synthetase deficiency]],  [[carbohydrate deficient glycoprotein syndrome type 1a]],  [[Porphyria|Chester porphyria]],  [[citrullinemia]],  [[cytosine arabinoside]],  [[erythropoietic protoporphyria]],  [[GM2 gangliosidosis]],  [[Hartnup disease]],  [[Ornithine translocase deficiency|homocitrullinuria syndrome]],  [[hypobetalipoproteinemia]],  [[hypocalcemia]],  [[hypoglycemia]],  [[hyponatremia]],  [[isovaleric acidemia]],  [[Lesch-Nyhan syndrome]],  [[Maple syrup urine disease]],  [[metabolic acidosis]],  [[Biotinidase deficiency|multiple carboxylase deficiency]],  [[Amblyopia|nutritional amblyopia]],  [[ornithine transcarbamylase deficiency]],  [[Phenylketonuria|phenylalanine hydroxylase deficiency]],  [[porphyria]],  [[pyruvate carboxylase deficiency]],  [[pyruvate dehydrogenase deficiency]],  [[Strachan syndrome]],  [[uremia]],  [[Wilson disease]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| [[Childbirth]],  [[menopause]],  [[pregnancy]]
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Acoustic neuroma]],  [[Medulloblastoma|cerebellar tumors]],  [[chondroma]],  [[Ewing's sarcoma]],  [[Hodgkin's lymphoma]],  [[lung carcinoma]],  [[neuroblastoma]],  [[neurofibromatosis type 1]],  [[Non-Hodgkin lymphoma|non-Hodgkin's lymphoma]],  [[osteochondroma]],  [[osteoma]],  [[osteosarcoma]],  [[paraneoplastic syndrome]],  [[rhabdomyosarcoma]],  [[plasmacytoma]],  [[spinal cord tumor]]
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Cataract]],  [[central serous chorioretinopathy]],  [[cortical visual impairment]],  [[endophthalmitis]],  [[Dyskeratosis congenita|Hoyeraal-Hreidarsson syndrome]],  [[hyphema]],  [[Guillain-Barré syndrome|Miller-Fisher syndrome]],  [[ocular ischemic syndrome]],  [[ophthalmia neonatorum]],  [[progressive external ophthalmoplegia]],  [[retinal degeneration]],  [[retrolental fibroplasia]],  [[visual impairment]],  [[vitreous hemorrhage]]
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Ethanol|Alcohol toxicity]]
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| [[Asthma|Asthma exacerbation]],  [[Chronic obstructive pulmonary disease|chronic obstructive pulmonary disease exacerbation]],  [[Idiopathic pulmonary fibrosis|diffuse pulmonary fibrosis]],  [[pleural effusion]],  [[pneumonia]],  [[pneumothorax]],  [[pulmonary edema]],  [[pulmonary embolism]]
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Renal failure]]
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Acute disseminated encephalomyelitis natural history, complications and prognosis|Acute demyelinating encephalomyelitis]],  [[ankylosing spondylitis]],  [[antiphospholipid antibody syndrome]],  [[benign monoclonal gammopathy]],  [[connective tissue disease]],  [[dermatomyositis]],  [[fibromyalgia]],  [[gout]],  [[Guillain-Barré syndrome]],  [[lymphomatoid granulomatosis]],  [[microscopic polyangiitis]],  [[mixed connective tissue disease]],  [[monoclonal gammopathy]],  [[polyarteritis nodosa]],  [[pseudogout]],  [[Reiter's syndrome]],  [[rheumatoid arthritis]],  [[scleroderma]],  [[seronegative spondyloarthritis]],  [[Sjögren's syndrome]],  [[systemic lupus erythematosus]]
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| [[Intracranial hemorrhage|Cerebellar hemorrhage]],  [[head injury]],  [[Bone fracture|leg fractures]]
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| [[Amyloidosis]],  [[cryoglobulinemia]],  [[dysproteinemia]],  [[emotions]],  [[Fatigue|generalized weakness]],  [[hyperventilation]],  [[metachromatic leukodystrophy]],  [[multiple hamartoma syndrome]],  [[Niemann-Pick disease]],  [[old age]],  [[pain]],  [[paraproteinemia]],  [[Salla disease]],  [[sarcoidosis]],  [[Shy-Drager syndrome]],  [[sialidosis]],  [[Tay-Sachs disease]]
|-
|}


===Causes in Alphabetical Order===
==[[Disequilibrium causes|Causes]]==
{{col-begin|width=85%}}
{{col-break|width=33%}}
*[[2-hydroxyglutarate dehydrogenase|2-hydroxyglutarate dehydrogenase deficiency]]
*[[3-methylglutaconic aciduria]]
*[[Leukoencephalopathy|4H syndrome]]
*[[Abetalipoproteinemia]]
*[[Acoustic neuroma]]
*[[Acromegaly]]
*[[Acrylamide]]
*[[Acute coronary syndrome]]
*[[Acute disseminated encephalomyelitis natural history, complications and prognosis|Acute demyelinating encephalomyelitis]]
*[[Acute intermittent porphyria]]
*[[Myelopathy|Acute necrotizing myelopathy]]
*[[Transverse myelitis|Acute viral myelitis]]
*[[Adrenoleukodystrophy]]
*[[Adrenomyeloneuropathy]]
*[[AIDS]]
*[[Alcohol dependence]]
*[[Ethanol|Alcohol toxicity]]
*[[Alcoholic polyneuropathy]]
*[[Alpha-mannosidase deficiency]]
*[[AMACR|Alpha-methylacyl-coa racemase deficiency]]
*[[Altitude sickness]]
*[[Aminophylline]]
*[[Amiodarone]]
*[[Amphotericin B]]
*[[Amyloidosis]]
*[[Amyotrophic lateral sclerosis]]
*[[Anemia]]
*[[Ankylosing spondylitis]]
*[[Antihypertensives]]
*[[Cerebellar ataxia|Anti-glutamic acid decarboxylase associated cerebellar ataxia]]
*[[Antibiotics]]
*[[Anticholinergics]]
*[[Anticonvulsants]]
*[[Antidepressants]]
*[[Antiphospholipid antibody syndrome]]
*[[Anxiety]]
*[[Argininosuccinic aciduria]]
*[[Arnold-Chiari malformation]]
*[[Arrhythmia]]
*[[Arsenic]]
*[[Arteriosclerosis]]
*[[Metachromatic leukodystrophy|Arylsulphatase A deficiency]]
*[[Aspartoacylase deficiency]]
*[[Aspirin]]
*[[Asthma|Asthma exacerbation]]
*[[Apraxia|Ataxia-oculomotor apraxia]]
*[[Ataxia-telangiectasia]]
*[[Cutis laxa|ATP6V0A2-related cutis laxa]]
*[[Aurothioglucose]]
*[[Migraine|Basilar migraine]]
*[[Benign monoclonal gammopathy]]
*[[Benign paroxysmal vertigo]]
*[[Beri-beri]]
*[[Biguanide]]
*[[Bilateral frontoparietal polymicrogyria]]
*[[Biotinidase deficiency]]
*[[Borrelia burgdorferi]]
*[[Bortezomib]]
*[[Botulism]]
*[[Encephalitis|Brainstem encephalitis]]
*[[Somatization disorder|Briquet's syndrome]]
*[[Brucellosis]]
*[[Capecitabine]]
*[[Carbachol]]
*[[Carbamoylphosphate synthetase deficiency]]
*[[Carbohydrate deficient glycoprotein syndrome type 1a]]
*[[Carbon tetrachloride]]
*[[Cardiomyopathy]]
*[[Carotid-cavernous fistula]]
*[[Carpal tunnel syndrome]]
*[[Cataract]]
*[[Celecoxib]]
*[[Celiac disease]]
*[[Central serous chorioretinopathy]]
*[[Cerebellar abscess]]
*[[Cerebellar hypoplasia]]
*[[Cerebellar ataxia]]
*[[Ramsay-Hunt syndrome|Cerebellar dyssynergia]]
*[[Intracranial hemorrhage|Cerebellar hemorrhage]]
*[[Medulloblastoma|Cerebellar tumor]]
*[[Dandy-Walker syndrome|Cerebellar vermis agenesis]]
*[[Cerebral palsy]]
*[[Cerebrotendineous xanthomatosis]]
*[[Cerebrovascular disease]]
*[[Ceroid lipofuscinosis]]
*[[Cervical spondylosis]]
*[[Charcot-Marie-Tooth Syndrome|Charcot-Marie-Tooth disease]]
*[[SACS (gene)|Charlevoix-saguenay spastic ataxia]]
*[[Porphyria|Chester porphyria]]
*[[Chickenpox]]
*[[Childbirth]]
*[[Chlorpheniramine]]
*[[Chondroma]]
*[[Chronic liver disease]]
*[[Chronic obstructive pulmonary disease|Chronic obstructive pulmonary disease exacerbation]]
*[[Cinnarizine]]
*[[Cisplatin]]
*[[Citrullinemia]]
*[[Claude syndrome]]
*[[Clomifene]]
*[[Cockayne syndrome]]
*[[Mitochondrial disease|Coenzyme Q10 deficiency]]
*[[Colchicine]]
*[[Cold exposure]]
*[[Compartment syndrome]]
*[[Delirium|Confusional state]]
*[[Congestive cardiac failure]]
*[[Connective tissue disease]]
*[[Copper deficiency|Copper deficiency myeloneuropathy]]
*[[Cortical visual impairment]]
*[[Coxsackie A virus]]
*[[Creutzfeldt-Jakob disease]]
*[[Cryoglobulinemia]]
*[[Cysticercosis]]
*[[Cytomegalovirus|Cytomegalovirus polyradiculopathy]]
*[[Cytosine arabinoside]]
*[[Dandy-Walker syndrome]]
*[[Dapsone]]
*[[Neuropathy|Deafferentation]]
*[[Myelopathy|Decompression sickness myelopathy]]
*[[De Grouchy Syndrome]]
*[[Dehydration]]
*[[Dejerine Sottas syndrome]]
*[[Dementia]]
*[[Demyelination]]
*[[Dentatorubral-pallidoluysian atrophy]]
*[[Depression]]
*[[Dermatomyositis]]
*[[Diabetes mellitus]]
*[[Diabetic amyotrophy]]
*[[Diabetic ketoacidosis]]
*[[Diabetic neuropathy|Diabetic radiculopathy]]
*[[Idiopathic pulmonary fibrosis|Diffuse pulmonary fibrosis]]
*[[Schilder's disease|Diffuse sclerosis of Schilder]]
*[[Diphenhydramine]]
*[[Diphtheria]]
*[[Hereditary motor and sensory neuropathy|Distal hereditary neuronopathy]]
*[[Disulfiram]]
*[[Diuretics]]
*[[Dothiepin]]
*[[Duchenne muscular dystrophy]]
*[[Dural arteriovenous fistula]]
*[[Dysproteinemia]]
*[[Ramsay-Hunt syndrome|Dyssynergia cerebellaris myoclonica]]
*[[Electrical injury]]
{{col-break|width=33%}}
*[[Emotions]]
*[[Encephalocele]]
*[[Encephalomyelitis]]
*[[Endophthalmitis]]
*[[Epidural abscess]]
*[[Epilepsy]]
*[[Episodic ataxia]]
*[[Epstein-barr virus ]]
*[[Erythropoietic protoporphyria]]
*[[Ethambutol]]
*[[Ethotoin]]
*[[Ewing's sarcoma]]
*[[Fabry's disease]]
*[[Familial alphalipoprotein deficiency]]
*[[Worster-Drought syndrome|Familial danish dementia]]
*[[Familial hemiplegic migraine]]
*[[Neuropathy|Femoral neuropathy]]
*[[Intrauterine growth retardation|Fetal akinesia-hypokinesia sequence]]
*[[Fibromyalgia]]
*[[Fluorouracil]]
*[[Friedreich's ataxia]]
*[[Hyperkalemic periodic paralysis|Gamstorp-Wohlfart syndrome]]
*[[Fatigue|Generalized weakness]]
*[[Gerstmann-Sträussler-Scheinker syndrome]]
*[[Giant axonal neuropathy]]
*[[Glucose phosphate isomerase deficiency]]
*[[GM2 gangliosidosis]]
*[[Gout]]
*[[Griscelli syndrome]]
*[[Guillain-Barré syndrome]]
*[[Haemochromatosis]]
*[[Hartnup disease]]
*[[Haw river syndrome]]
*[[Head injury]]
*[[Heat stroke]]
*[[Heavy metals]]
*[[Hepatic cirrhosis]]
*[[Familial amyloid polyneuropathy|Hereditary amyloid polyneuropathy]]
*[[Hereditary ataxia]]
*[[Hereditary neuralgic amyotrophy]]
*[[Hereditary sensory and autonomic neuropathy]]
*[[Hereditary spastic paraplegia]]
*[[Spinal disc herniation|Herniated vertebral disc]]
*[[Herpes simplex]]
*[[Herpes zoster]]
*[[HIV]]
*[[Hodgkin's lymphoma]]
*[[Ornithine translocase deficiency|Homocitrullinuria syndrome]]
*[[Dyskeratosis congenita|Hoyeraal-Hreidarsson syndrome]]
*[[Huntington disease]]
*[[Hydralazine]]
*[[Hydroxyzine ]]
*[[Hypertension]]
*[[Hyperthyroidism]]
*[[Hyperventilation syndrome]]
*[[Hyperventilation]]
*[[Hyphema]]
*[[Hypobetalipoproteinemia]]
*[[Hypocalcemia]]
*[[Hypochondriasis]]
*[[Hypoglycemia]]
*[[Hyponatremia]]
*[[Hypoparathyroidism]]
*[[Hypotension]]
*[[Hypothyroidism ]]
*[[Hypoxia]]
*[[Hysteria]]
*[[Neuropathy|Idiopathic lumbosacral radiculoplexus neuropathy]]
*[[Small fiber peripheral neuropathy|Idiopathic small fiber neuropathy]]
*[[Hearing impairment|Impaired hearing]]
*[[Fistula|Intestinal fistula]]
*[[Intracranial space-occupying lesion]]
*[[Isoniazid]]
*[[Isovaleric acidemia]]
*[[Ixabepilone]]
*[[Joubert syndrome]]
*[[Kearns-Sayre syndrome]]
*[[Klumpke paralysis]]
*[[Konzo]]
*[[Lamivudine]]
*[[Lathyrism]]
*[[Lead]]
*[[Leflunomide]]
*[[Bone fracture|Leg fractures]]
*[[Leigh syndrome]]
*[[Leprosy]]
*[[Lesch-Nyhan syndrome]]
*[[Leukemia]]
*[[Linezolid]]
*[[Lithium ]]
*[[Loken Senior syndrome]]
*[[Flaccid paralysis|Lower motor neuron weakness]]
*[[Plexopathy|Lumbosacral plexitis]]
*[[Lung carcinoma]]
*[[Lyme disease]]
*[[Lymphomatoid granulomatosis]]
*[[Machado-Joseph disease]]
*[[Major depression]]
*[[Malaria]]
*[[Malingering]]
*[[Maple syrup urine disease]]
*[[Marinesco-Sjogren syndrome]]
*[[Mefloquine ]]
*[[Melarsoprol]]
*[[MELAS]]
*[[Meningoencephalitis]]
*[[Menopause]]
*[[Meralgia paresthetica]]
*[[Mercury]]
*[[MERRF]]
*[[Metabolic acidosis]]
*[[Metachromatic leukodystrophy]]
*[[Methanol]]
*[[Metronidazole]]
*[[Microscopic polyangiitis]]
*[[Migraine ]]
*[[Guillain-Barré syndrome|Miller-Fisher syndrome]]
*[[Mitochondrial disease|Mitochondrial ataxia]]
*[[Mixed connective tissue disease]]
*[[Monoclonal gammopathy]]
*[[MPV17|MPV17 gene mutation]]
*[[Multifocal motor neuropathy]]
*[[Biotinidase deficiency|Multiple carboxylase deficiency]]
*[[Multiple hamartoma syndrome]]
*[[Multiple lentigines syndrome]]
*[[Multiple myeloma]]
*[[Multiple sclerosis]]
*[[Neuropathy|Multiple sensory defect dizziness]]
*[[Shy-Drager syndrome|Multiple system atrophy syndromes]]
*[[Muscle weakness ]]
*[[Myasthenia gravis]]
*[[Mycoplasma pneumoniae]]
*[[Myelopathy]]
*[[Myocardial infarction]]
*[[Nalidixic acid]]
*[[Neuropathy, ataxia, and retinitis pigmentosa|NARP syndrome]]
*[[Neuroblastoma]]
*[[Neurofibromatosis type 1]]
*[[Neuroleptics]]
*[[Neuronal ceroid lipofuscinosis]]
*[[Niemann-Pick disease]]
*[[Nitrofurantoin]]
*[[Non-Hodgkin's lymphoma]]
*[[Normal pressure hydrocephalus]]
{{col-break|width=33%}}
*[[Nortriptyline]]
*[[Claude syndrome|Nothnagel Claude syndrome]]
*[[Nucleoside analogues ]]
*[[Amblyopia|Nutritional amblyopia]]
*[[Obturator nerve|Obturator neuropathy]]
*[[Ocular ischemic syndrome]]
*[[Old age]]
*[[Olivopontocerebellar atrophy]]
*[[Ophthalmia neonatorum]]
*[[Organophosphates]]
*[[Ornithine transcarbamylase deficiency]]
*[[Myoclonus|Orthostatic myoclonus]]
*[[Osteoarthritis]]
*[[Osteochondroma]]
*[[Osteoma]]
*[[Osteomyelitis]]
*[[Osteosarcoma]]
*[[Oxaliplatin]]
*[[Paclitaxel]]
*[[Pagets disease]]
*[[Pain]]
*[[Pantothenate kinase]]
*[[Paraneoplastic cerebellar degeneration]]
*[[Neuropathy|Paraneoplastic sensory neuropathy]]
*[[Paraneoplastic syndrome]]
*[[Paraproteinemia]]
*[[Parkinson disease]]
*[[Pelizaeus-Merzbacher disease]]
*[[Peripheral neuropathy]]
*[[Pernicious anemia]]
*[[Neuropathy|Peroneal compression at the fibular neck]]
*[[Perthes disease]]
*[[Phaeochromocytoma]]
*[[Phenylketonuria|Phenylalanine hydroxylase deficiency]]
*[[Phenylbutazone ]]
*[[Phenytoin]]
*[[Physostigmine]]
*[[Plasmacytoma]]
*[[Pleural effusion]]
*[[Pneumonia]]
*[[Pneumothorax]]
*[[Polyarteritis nodosa]]
*[[Polycythemia vera]]
*[[Polymyositis]]
*[[Polyrediculitis]]
*[[Porphyria]]
*[[Posterior inferior cerebellar artery syndrome]]
*[[Posterior leucoencephalopathy syndrome]]
*[[Postural hypotension]]
*[[Pregnancy]]
*[[Primary biliary cirrhosis]]
*[[Prochlorperazine ]]
*[[Progressive external ophthalmoplegia]]
*[[Pseudogout]]
*[[Pulmonary edema]]
*[[Pulmonary embolism]]
*[[Pyloric stenosis]]
*[[Pyridoxine]]
*[[Pyruvate carboxylase deficiency]]
*[[Pyruvate dehydrogenase deficiency]]
*[[Radiotherapy]]
*[[Raised intracranial pressure]]
*[[Refsum disease]]
*[[Reiter's syndrome]]
*[[Renal failure]]
*[[Retinal degeneration]]
*[[Retrolental fibroplasia ]]
*[[Rhabdomyosarcoma]]
*[[Rheumatoid arthritis]]
*[[Rofecoxib]]
*[[Charcot-Marie-Tooth Syndrome|Roussy-levy disease]]
*[[Salicylate poisoning]]
*[[Salla disease]]
*[[Sandhoff disease]]
*[[Sarcoidosis]]
*[[Schistosoma]]
*[[Schizophrenia]]
*[[Neuropathy|Sciatic neuropathy]]
*[[Scleroderma]]
*[[Sedatives ]]
*[[Septic arthritis]]
*[[Septicemia]]
*[[Seronegative spondyloarthritis]]
*[[KCNJ10|SeSAME syndrome]]
*[[Shy-Drager syndrome]]
*[[Sialidosis]]
*[[Sideroblastic anemia]]
*[[Silver-Russell dwarfism|Silver syndrome]]
*[[Sjögren's syndrome]]
*[[Slipped upper femoral epiphysis]]
*[[Arteriovenous malformation|Spinal arteriovenous malformations]]
*[[Spinal cord tumor]]
*[[Epidural hematoma|Spinal epidural hematoma]]
*[[Spinocerebellar ataxia]]
*[[Stavudine]]
*[[Strachan syndrome]]
*[[Stroke]]
*[[Subacute combined degeneration of spinal cord|Subacute combined degeneration]]
*[[Leigh's disease|Subacute necrotising encephalomyelopathy]]
*[[Neuropathy|Subacute sensory neuronopathy]]
*[[Superior orbital fissure|Superior orbital fissure syndrome]]
*[[Suramin]]
*[[Syphilis]]
*[[Syringobulbia]]
*[[Syringomyelia]]
*[[Systemic lupus erythematosus]]
*[[Tarsal tunnel syndrome]]
*[[Taxol]]
*[[Tay-Sachs disease]]
*[[Thallium]]
*[[Thiamine deficiency]]
*[[Tick paralysis]]
*[[Toluene]]
*[[Tropical sprue]]
*[[Trabectedin]]
*[[Tranquilizers]]
*[[Transient ischemic attack]]
*[[Transient synovitis]]
*[[Transverse myelitis ]]
*[[Treponema pallidum]]
*[[SPG20|Troyer syndrome]]
*[[Tuberculosis]]
*[[Typhoid fever]]
*[[Unverricht-Lundborg disease]]
*[[Spasticity|Upper motor neuron weakness]]
*[[Uremia]]
*[[Urination]]
*[[Vaccines]]
*[[Van der Knaap disease]]
*[[Vasculitis]]
*[[Vasovagal syncope|Vasovagal attacks]]
*[[Vertebral artery dissection]]
*[[Verteporfin]]
*[[Vertigo|Vestibular disorder]]
*[[Vigabatrin]]
*[[Vincristine]]
*[[Viral hepatitis]]
*[[Visual impairment]]
*[[Vitamin B1 deficiency]]
*[[Vitreous hemorrhage]]
*[[Von Hippel-Lindau syndrome]]
*[[Wilson disease]]
*[[Xeroderma pigmentosum]]
*[[Zalcitabine]]
{{col-end}}


== References ==
==[[Disequilibrium differential diagnosis|Differentiating Disequilibrium from other Diseases]]==
{{Reflist|2}}


[[Category:Signs and symptoms]]
==[[Disequilibrium epidemiology and demographics|Epidemiology and Demographics]]==
[[Category:Otolaryngology]]
[[Category:Neurology]]
[[Category:Musculoskeletal disorders]]
[[Category:Up-To-Date]]


{{WH}}
==[[Disequilibrium risk factors|Risk Factors]]==
{{WS}}
 
==[[Disequilibrium natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
 
[[Disequilibrium history and symptoms|History and Symptoms ]] | [[ Disequilibrium physical examination|Physical Examination]] | [[Disequilibrium laboratory findings|Laboratory Findings]] | [[Disequilibrium CT|CT]] | [[Disequilibrium other imaging findings|Other Imaging Findings]] | [[Disequilibrium other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Disequilibrium medical therapy|Medical Therapy]] | [[Disequilibrium surgery|Surgery]] | [[Disequilibrium primary prevention|Primary Prevention]] | [[Disequilibrium secondary prevention|Secondary Prevention]] | [[Disequilibrium cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Disequilibrium future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Disequilibrium case study one|Case #1]]

Latest revision as of 03:58, 1 August 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]

Synonyms and keywords: Bad balance; chronic dizziness; imbalance; instability; loss of balance; off balance; unsteadiness

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Disequilibrium from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1