Diloxanide furoate

Jump to navigation Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Diloxanide
Clinical data
Trade namesFuramide
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • No available data
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • Not approved (US, CA)
Pharmacokinetic data
Bioavailability90% (diloxanide)
MetabolismHydrolyzed to furoic acid and diloxanide, which undergoes extensive glucuronidation
Elimination half-life3 hours
ExcretionRenal (90%), fecal (10%)
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC14H11Cl2NO4
Molar mass328.147 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

WikiDoc Resources for Diloxanide furoate

Articles

Most recent articles on Diloxanide furoate

Most cited articles on Diloxanide furoate

Review articles on Diloxanide furoate

Articles on Diloxanide furoate in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Diloxanide furoate

Images of Diloxanide furoate

Photos of Diloxanide furoate

Podcasts & MP3s on Diloxanide furoate

Videos on Diloxanide furoate

Evidence Based Medicine

Cochrane Collaboration on Diloxanide furoate

Bandolier on Diloxanide furoate

TRIP on Diloxanide furoate

Clinical Trials

Ongoing Trials on Diloxanide furoate at Clinical Trials.gov

Trial results on Diloxanide furoate

Clinical Trials on Diloxanide furoate at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Diloxanide furoate

NICE Guidance on Diloxanide furoate

NHS PRODIGY Guidance

FDA on Diloxanide furoate

CDC on Diloxanide furoate

Books

Books on Diloxanide furoate

News

Diloxanide furoate in the news

Be alerted to news on Diloxanide furoate

News trends on Diloxanide furoate

Commentary

Blogs on Diloxanide furoate

Definitions

Definitions of Diloxanide furoate

Patient Resources / Community

Patient resources on Diloxanide furoate

Discussion groups on Diloxanide furoate

Patient Handouts on Diloxanide furoate

Directions to Hospitals Treating Diloxanide furoate

Risk calculators and risk factors for Diloxanide furoate

Healthcare Provider Resources

Symptoms of Diloxanide furoate

Causes & Risk Factors for Diloxanide furoate

Diagnostic studies for Diloxanide furoate

Treatment of Diloxanide furoate

Continuing Medical Education (CME)

CME Programs on Diloxanide furoate

International

Diloxanide furoate en Espanol

Diloxanide furoate en Francais

Business

Diloxanide furoate in the Marketplace

Patents on Diloxanide furoate

Experimental / Informatics

List of terms related to Diloxanide furoate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Diloxanide furoate is a luminal amebicide used in the treatment of Amebiasis. It is considered the luminal agent of choice for mild intestinal amebiasis or asymptomatic cyst carriers.It can also be added to metronidazole(active drug in luminal and extraintestinal amebiasis) in acute amebic dysentery as well as hepatic abscess(In hepatic abscess it is for the control of cysts in the lumen which may cause relapse). The drug was discovered by The Boots Company Plc in 1956 and introduced as Furamide. The Furamide brand is now owned by Abbott Laboratories. It is not available in the US. In India it is available as Amicline by Franco-Indian.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Safety and effectiveness

A 13-year study conducted by the United States Center for Disease Control between 1977 and 1990 found that this drug had a low incidence of side effects and was successful in treatment of 86% of asymptomatic carriers of Entamoeba histolytica.

References