Diffuse large B cell lymphoma risk factors

Jump to navigation Jump to search

Diffuse large B cell lymphoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Diagnosis

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Biopsy

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Diffuse large B cell lymphoma risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Diffuse large B cell lymphoma risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Diffuse large B cell lymphoma risk factors

CDC on Diffuse large B cell lymphoma risk factors

Diffuse large B cell lymphoma risk factors in the news

Blogs on Diffuse large B cell lymphoma risk factors

Directions to Hospitals Treating Diffuse large B cell lymphoma

Risk calculators and risk factors for Diffuse large B cell lymphoma risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2] Anila Hussain, MD [3]

Overview

According to the American Cancer Society, There are several Factors including Old Age, Male Gender, White Ethnicity, Geography, exposure to Certain Drugs and Chemicals, Radiation exposure, and weak Immune System that can increase the chances of getting Non Hodgkin Lymphoma(NHL) among which Diffuse Large B cell Lymphoma is the Most common sub-type.

Risk factors:

Age:

Old age is a strong risk Factor for Lymphoma Overall with majority of cases occurring in age 60 or more, however some cases can be seen in young population which depends upon the type of Lymphoma

Gender:

Overall Risk of Non-Hodgkin Lymphoma is higher in men than in women, but there are certain types that are more commonly seen in women. Reasons to these are unknown

Race, Ethnicity and Geography:

In USA, Non Hodgkin Lymphoma is most commonly seen in white population than African-Americans or Asian-Americans

Worldwide, it is more common in developed countries with USA and Europe having the highest prevalence.

Drug and Chemical Exposure:

Some chemicals like Benzene and Herbicides and Insecticides may be associated with an increase Risk of NHL but Research is under progress to clarify these links. Some Chemotherapeutic Drugs might be associated as treatment for Hodgkin Lymphoma increases the risk of NHL but it is unclear whether it is treatment related or related to disease itself

Radiation:

There is an increased risk of many types of cancers in people exposed to high intensity. For example Survivors of many nuclear reactor accidents and atomic bombs have found to have certain types of cancers including NHL, Leukemia and Thyroid cancer. Also people with Hodgkin Lymphoma who get treated with Radiation have a slightly increased incidence to develop NHL later in life

Immunodeficiency:

There is an increased risk of NHL in people with immunodeficiency. Examples include Organ Transplant Recipients who are on Immunosuppressive drugs, HIV Infection. Some genetic conditions in which children are born with weak immune system like Wiskott-Aldrich Syndrome and Ataxia-telengectasia(AT) also have higher risk of NHL.

Autoimmune:

Some autoimmune diseases also increase the risk of cancer slightly.

References


Template:WikiDoc Sources