Differentiating Scleroderma from other diseases
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
OR
[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].
Differentiating X from other Diseases
- [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
- [Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
- As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
Preferred Table
Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | Physical examination | |||||||||||||||
Lab Findings | Imaging | Histopathology | ||||||||||||||
Symptom 1 | Symptom 2 | Symptom 3 | Physical exam 1 | Physical exam 2 | Physical exam 3 | Lab 1 | Lab 2 | Lab 3 | Imaging 1 | Imaging 2 | Imaging 3 | |||||
Systemic diseases | Scleroderma | |||||||||||||||
Scleromyxedema | ||||||||||||||||
Amyloidosis | ||||||||||||||||
Eosinophilic fasciitis | ||||||||||||||||
Chronic graft-versus-host disease | ||||||||||||||||
Drug induced scleroderma | ||||||||||||||||
Scleroderma overlap syndromes | Systemic lupus erythematosus | |||||||||||||||
Dermatomyositis | ||||||||||||||||
Rheumatoid arthritis | ||||||||||||||||
Endocrine disorders | Diabetes mellitus (diabetic cheiroarthropathy) | |||||||||||||||
Myxedema due to hypothyroidism | ||||||||||||||||
POEMS syndrome | ||||||||||||||||
Renal diseases | Nephrogenic systemic fibrosis |