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==Overview==
==Overview==
[[Diastolic dysfunction]], in the presence or absence of [[diastolic heart failure]], is a challenging diagnosis that has several diagnostic approaches. While [[cardiac catheterization]] can be used to establish the diagnosis of [[diastolic dysfunction]] by the invasive measurement of elevated left ventricular end diastolic pressure and mean pulmonary capillary pressure, [[echocardiography]] provides an alternative noninvasive diagnostic tool.
Cardiac catheterization can be used to measure the [[PCWP]] and the [[LVEDP]]. These are important predictors of the filling pressure and the degree of myocardial disease progression in dilated cardiomyopathy.
 
==Other Diagnostic Studies==
==Other Diagnostic Studies==
===Cardiac Catheterization===
===Cardiac Catheterization===
The predictors of the filling pressure and the degree of myocardial disease progression are essentially the [[mean pulmonary wedge pressure]] (PCWP, which is equal to the mean left atrial pressure in the absence of mitral stenosis) and the [[left ventricular end diastolic pressure]] (LVEDP).
The predictors of the filling pressure and the degree of myocardial disease progression are essentially the mean pulmonary wedge pressure ([[PCWP]], which is equal to the mean left atrial pressure in the absence of [[mitral stenosis]]) and the [[left ventricular end diastolic pressure]] (LVEDP).
*The diastolic phase of the [[cardiac cycle]] is normally characterized by rapid blood filling at low left ventricular pressures
*The diastolic phase of the [[cardiac cycle]] is normally characterized by rapid blood filling at low left ventricular pressures
*The hallmark of [[diastolic dysfunction]] is elevated left ventricular end diastolic pressure or filling pressure
*The hallmark of [[diastolic dysfunction]] is elevated left ventricular end diastolic pressure or filling pressure
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[[Category:Cardiovascular diseases]]
[[Category:Cardiovascular diseases]]
[[Category:Cardiomyopathy]]
[[Category:Cardiomyopathy]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Up-To-Date cardiology]]
[[Category:Up-To-Date]]

Latest revision as of 12:09, 30 January 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby

Overview

Cardiac catheterization can be used to measure the PCWP and the LVEDP. These are important predictors of the filling pressure and the degree of myocardial disease progression in dilated cardiomyopathy.

Other Diagnostic Studies

Cardiac Catheterization

The predictors of the filling pressure and the degree of myocardial disease progression are essentially the mean pulmonary wedge pressure (PCWP, which is equal to the mean left atrial pressure in the absence of mitral stenosis) and the left ventricular end diastolic pressure (LVEDP).

  • The diastolic phase of the cardiac cycle is normally characterized by rapid blood filling at low left ventricular pressures
  • The hallmark of diastolic dysfunction is elevated left ventricular end diastolic pressure or filling pressure
  • Cardiac catheterization is an invasive diagnostic tool used to measure the PCWP and the LVEDP
  • The cut off values used for the diagnosis of diastolic dysfunction are:
    • PCWP >12 mmHg
    • LVEDP> 16mmHg [1]

References

  1. Paulus WJ, Tschope C, Sanderson JE, Rusconi C, Flachskampf FA, Rademakers FE, et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J 2007;28: 2539-50.

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