De Quervain's thyroiditis medical therapy

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De Quervain's thyroiditis Microchapters


Patient Information


Historical Perspective




Differentiating De Quervain's thyroiditis from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications, and Prognosis


Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings


Chest X Ray



Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies


Medical Therapy


Primary prevention

Secondary prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]


The mainstay of therapy for de Quervain's thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms. Corticosteroids are usually used in severely ill patients. Levothyroxine is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state.

Medical Therapy

De Quervain's thyroiditis

The drugs used in the treatment of de Quervain's thyroiditis are:[1][2][3][4]

  • For pain
    • Preferred regimen (1): Naproxen: 500 to 1000 mg per day in two divided doses
    • Preferred regimen (2): Ibuprofen: 1200 to 3200 mg per day in three or four divided doses
  • For severe condition
    • Preferred regimen (1): Prednisone: 40 mg per day orally
  • For hypothyroidism
  • Preferred regimen (1): Synthetic levothyroxine (L-T4): 1.6–1.8 μg/kg per day orally
  • For thyrotoxic symptoms
    • Preferred regimen (1): atenolol: 25-200mg per day orally
    • Preferred regimen (2): metoprolol: 25-200mg per day orally


  1. Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
  2. Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K (1987). "Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis". Clin. Endocrinol. (Oxf). 27 (3): 339–44. PMID 3427792.
  3. Volpé R (1993). "The management of subacute (DeQuervain's) thyroiditis". Thyroid. 3 (3): 253–5. PMID 8257868.
  4. Feely J, Peden N (1984). "Use of beta-adrenoceptor blocking drugs in hyperthyroidism". Drugs. 27 (5): 425–46. PMID 6144501.