DNASE1L1

Deoxyribonuclease I-like 1
Identifiers
Symbols	DNASE1L1 ; DNAS1L1; DNL1L; XIB
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4896
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Deoxyribonuclease I-like 1, also known as DNASE1L1, is a human gene.

This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Further reading

• Parrish JE, Ciccodicola A, Wehhert M; et al. (1996). "A muscle-specific DNase I-like gene in human Xq28". Hum. Mol. Genet. 4 (9): 1557–64. PMID 8541839.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pergolizzi R, Appierto V, Bosetti A; et al. (1996). "Cloning of a gene encoding a DNase I-like endonuclease in the human Xq28 region". Gene. 168 (2): 267–70. PMID 8654957.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen EY, Zollo M, Mazzarella R; et al. (1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum. Mol. Genet. 5 (5): 659–68. PMID 8733135.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rodriguez AM, Rodin D, Nomura H; et al. (1997). "Identification, localization, and expression of two novel human genes similar to deoxyribonuclease I.". Genomics. 42 (3): 507–13. doi:10.1006/geno.1997.4748. PMID 9205125.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malferrari G, Mazza U, Tresoldi C; et al. (1999). "Molecular characterization of a novel endonuclease (Xib) and possible involvement in lysosomal glycogen storage disorders". Exp. Mol. Pathol. 66 (2): 123–30. doi:10.1006/exmp.1999.2254. PMID 10409440.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ross MT, Grafham DV, Coffey AJ; et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shiokawa D, Shika Y, Saito K; et al. (2006). "Physical and biochemical properties of mammalian DNase X proteins: non-AUG translation initiation of porcine and bovine mRNAs for DNase X.". Biochem. J. 392 (Pt 3): 511–7. doi:10.1042/BJ20051114. PMID 16107205.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Coy JF, Velhagen I, Himmele R; et al. "Isolation, differential splicing and protein expression of a DNase on the human X chromosome". Cell Death Differ. 3 (2): 199–206. PMID 17180083.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)