Cutis laxa: Difference between revisions

	Cutis laxa;
ICD-10	Q82.8
OMIM	219100
DiseasesDB	29117
eMedicine	derm/03
MeSH	D003483

VisualWikitext

Revision as of 18:18, 21 August 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Cutis laxa (also called elastolysis) is a group of rare connective tissue disorders in which the skin becomes inelastic and hangs loosely in folds. In most cases, cutis laxa is inherited. Autosomal dominant, autosomal recessive and X-linked recessive forms have been described, but acquired forms also occur. It is characterized by skin that is loose, hanging, wrinkled, and lacking in elasticity. The loose skin is often most noticeable on the face, resulting in a prematurely aged appearance. The affected areas of skin may be thickened and dark. In addition, the joints are loose (hypermobility) because of lax ligaments and tendons. When cutis laxa is severe, it can also affect the internal organs. The lungs, heart, intestines, or arteries may be affected with a variety of severe impairments. In some cases hernias, and outpouching of the bladder can be observed.

In patients suffering from Cutis Laxa mutations in the elastic fibers comprising the dermis have been identified.

Diagnosis

Physical Examination

Skin

Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]
Cutis laxa. Adapted from Dermatology Atlas.^[1]

External links

Template:DermAtlas

Template:Disease-stub Template:Congenital malformations and deformations of integument

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 ^1.15 "Dermatology Atlas".

[Dermatology_Atlas-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 ^1.15 "Dermatology Atlas".

[1]

@@ Line 35: / Line 35: @@
 Image:Cutis laxa11.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 Image:Cutis laxa12.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
-Image:Cutis laxa13.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 Image:Cutis laxa14.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 Image:Cutis laxa15.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
@@ Line 41: / Line 40: @@
 Image:Cutis laxa17.jpg|Cutis laxa. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 </gallery>
 ==External links==

Cutis laxa
ICD-10	Q82.8
OMIM	219100
DiseasesDB	29117
eMedicine	derm/03
MeSH	D003483