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{{Cushing's syndrome}}
{{Cushing's syndrome}}  


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{{CMG}} {{AE}} {{MMF}}


==Overview==
==Overview==
Symptoms of Cushing's syndrome include  rapid [[obesity|weight gain]], particularly of the trunk and face with sparing of the limbs ([[central obesity]]), a round face often referred to as a "[[moon face]]", excess [[sweating]], [[insomnia]], reduced [[libido]], [[impotence]], [[amenorrhoea]], [[infertility]] and psychological disturbances, ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]].<ref>{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |coauthors=Robert E. Hales |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref>
Symptoms of Cushing's syndrome include  rapid [[obesity|weight gain]], particularly of the [[trunk]] and [[face]] with sparing of the [[limbs]] ([[central obesity]]), a [[round face]] often referred to as a "[[moon face]]", excessive [[sweating]],[[insomnia]], reduced [[libido]], [[impotence]], [[amenorrhoea]], [[infertility]] and [[Psychological|psychological disturbances]], ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]] and may include [[clinical depression|depression]] and [[anxiety]].
 
==History==


==Symptoms==
==Symptoms==
Symptoms include
Symptoms of Cushing's syndrome include:<ref name="pmid26156970">{{cite journal |vauthors=Nieman LK |title=Cushing's syndrome: update on signs, symptoms and biochemical screening |journal=Eur. J. Endocrinol. |volume=173 |issue=4 |pages=M33–8 |year=2015 |pmid=26156970 |pmc=4553096 |doi=10.1530/EJE-15-0464 |url=}}</ref><ref name="The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences">{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref>
* Rapid [[obesity|weight gain]], particularly of the trunk and face with sparing of the limbs ([[central obesity]])
===Common Symptoms===
* A round face often referred to as a "[[moon face]]"
Common symptoms of Cushing's syndrome include:
* Excess [[sweating]]
* Rapid [[obesity|weight gain]], particularly of the [[trunk]] and [[face]] with sparing of  [[limbs]] ([[central obesity]])
* The excess cortisol may also affect other endocrine systems and cause, for example
*Proximal [[muscle weakness]]
** [[Insomnia]]
* A [[round face]] often referred to as a "[[moon face]]"
** Reduced [[libido]]
* Excessive [[sweating]]
** [[Impotence]]
*[[Headache]]
** [[Amenorrhoea]]
** [[Infertility]]
* Patients frequently suffer various psychological disturbances, ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]] are also common.<ref>{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |coauthors=Robert E. Hales |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref>  
 
Furthermore, [[gastrointestinal]] disturbances, opportunistic infections and impaired wound healing (cortisol is a stress hormone, so it depresses the immune and inflammatory responses).


[[Osteoporosis]] is also a problem in Cushing's Syndrome, as mentioned before, cortisol evokes a stress-like response. The body's maintenance of bone (and other tissues) is therefore no longer one of its main priorities, so to speak.
===Less Common Symptoms===
Less common symptoms of Cushing's syndrome include:
* [[Insomnia]]
*Decreased [[libido]]
*[[Impotence]]
* [[Amenorrhoea]]
*[[Infertility]]
*[[clinical depression|Depression]]
*[[Anxiety]]


==References==
==References==

Latest revision as of 19:43, 20 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Symptoms of Cushing's syndrome include rapid weight gain, particularly of the trunk and face with sparing of the limbs (central obesity), a round face often referred to as a "moon face", excessive sweating,insomnia, reduced libido, impotence, amenorrhoea, infertility and psychological disturbances, ranging from euphoria to psychosis and may include depression and anxiety.

Symptoms

Symptoms of Cushing's syndrome include:[1][2]

Common Symptoms

Common symptoms of Cushing's syndrome include:

Less Common Symptoms

Less common symptoms of Cushing's syndrome include:

References

  1. Nieman LK (2015). "Cushing's syndrome: update on signs, symptoms and biochemical screening". Eur. J. Endocrinol. 173 (4): M33–8. doi:10.1530/EJE-15-0464. PMC 4553096. PMID 26156970.
  2. Yudofsky, Stuart C. (2007). The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences (5th ed.). American Psychiatric Pub, Inc. ISBN 1585622397.


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