Cushing's syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Epidemiology and Demographics

The incidence of pituitary tumors causing Cushing's syndrome may be relatively high, as much as one in five people, [1] but only a minute fraction are active and produce excessive hormones.

Overview

Enterobiasis is particularly common in children. Annually, around 200 million people are infected worldwide. The pinworm is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe.

Epidemiology and Demographics

Cushing's disease is more common in females.

Prevalance

The prevalence of Cushing's syndrome is 39-79 per million.[2][3]

Incidence

The overall incidence of endogenous Cushing’s syndrome is approximately 2–5 new cases per million people per year.[2]

Age

There is no gender predilection for Cushing's syndrome.

Gender

Cushing's disease is more common in females with a female-to-male ratio of 3:1.[2]

Race

There is no racial predilection for enterobiasis.

Developed Countries

It is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe.

Developing Countries

Enterobiasis has a worldwide distribution.

References

  1. Ezzat S, Asa SL, Couldwell WT; et al. (2004). "The prevalence of pituitary adenomas: a systematic review". Cancer. 101 (3): 613–9. doi:10.1002/cncr.20412. PMID 15274075.
  2. 2.0 2.1 2.2 Lacroix A, Feelders RA, Stratakis CA, Nieman LK (2015). "Cushing's syndrome". Lancet. 386 (9996): 913–27. doi:10.1016/S0140-6736(14)61375-1. PMID 26004339.
  3. Loriaux DL (2017). "Diagnosis and Differential Diagnosis of Cushing's Syndrome". N. Engl. J. Med. 376 (15): 1451–1459. doi:10.1056/NEJMra1505550. PMID 28402781.


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