Cushing's syndrome (patient information)

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What is Cushing's syndrome

Cushing’s syndrome is a hormonal disorder caused by prolonged exposure of the body’s tissues to high levels of the hormone cortisol. Sometimes called hypercortisolism, Cushing’s syndrome is relatively rare and most commonly affects adults aged 20 to 50. People who are obese and have type 2 diabetes, along with poorly controlled blood glucose—also called blood sugar—and high blood pressure, have an increased risk of developing the disorder.

What are the Symptoms of Cushing's syndrome?

Signs and symptoms of Cushing’s syndrome vary, but most people with the disorder have:

• upper body obesity
• a rounded face
• increased fat around the neck
• relatively slender arms and legs
• Children tend to be obese with slowed growth rates.

Other signs appear in the skin, which becomes fragile and thin, bruises easily, and heals poorly. Purple or pink stretch marks may appear on the abdomen, thighs, buttocks, arms, and breasts. The bones are weakened, and routine activities such as bending, lifting, or rising from a chair may lead to backaches and rib or spinal column fractures.

Women with Cushing’s syndrome usually have excess hair growth on their face, neck, chest, abdomen, and thighs. Their menstrual periods may become irregular or stop. Men may have decreased fertility with diminished or absent desire for sex and, sometimes, erectile dysfunction.

Other common signs and symptoms include:

• severe fatigue
• weak muscles
• high blood pressure
• high blood glucose
• increased thirst and urination
• irritability, anxiety, or depression
• a fatty hump between the shoulders

Diseases With Similar Symptoms

• polycystic ovary syndrome
• metabolic syndrome

Where to find Medical Care for " "

Directions to Hospitals Treating Cushing's syndrome