Curling's ulcer
|
WikiDoc Resources for Curling's ulcer |
|
Articles |
|---|
|
Most recent articles on Curling's ulcer Most cited articles on Curling's ulcer |
|
Media |
|
Powerpoint slides on Curling's ulcer |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Curling's ulcer at Clinical Trials.gov Trial results on Curling's ulcer Clinical Trials on Curling's ulcer at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Curling's ulcer NICE Guidance on Curling's ulcer
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Curling's ulcer Discussion groups on Curling's ulcer Patient Handouts on Curling's ulcer Directions to Hospitals Treating Curling's ulcer Risk calculators and risk factors for Curling's ulcer
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Curling's ulcer |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Curling's ulcer is an acute peptic ulcer of the duodenum resulting as a complication from severe burns when reduced plasma volume leads to sloughing of the gastric mucosa. The condition was first described in 1823 and named for a doctor, Thomas Blizard Curling, who observed ten such patients in 1842.[1]
These stress ulcers were once a common complication of serious burns, presenting in over 10% of cases,[1] and especially common in child burn victims.[2] They result in perforation and hemorrhage more often than other forms of intestinal ulceration[3] and had correspondingly high mortality rates.[1] While emergency surgery was once the only treatment, combination therapies including enteral feeding with powerful antacids such as H2-receptor antagonists or, more recently, proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.[4]
A similar condition involving elevated intracranial pressure is known as Cushing ulcer.
References
- ↑ 1.0 1.1 1.2 Pruitt, Basil A., Jr., F.D. Foley and John A. Moncrief (Oct 1970). "Curling's Ulcer:A Clinical-Pathology Study of 323 Cases". Annals of Surgery. 172.
- ↑ Bruck, H.M. and Basil A. Pruitt, Jr. (Jun 1972). "Curling's ulcer in children: a 12-year review of 63 cases". Journal of Trauma. 12.
- ↑ Lev, Robert; et al. (Dec 1973). "Stress erosions". Digestive Diseases and Sciences. 18.
- ↑ Moran, K.T., T. O'Reilly and A.M. Munster (Oct 1987). "A combined regimen for the prophylaxis of Curling's ulcer". American Surgeons. 53.