Difference between revisions of "Cryopyrin-associated periodic syndrome (patient information)"

Jump to: navigation, search
(Created page with "__NOTOC__ {Cryopyrin-associated periodic syndrome} {{CMG}}; {{AE}} {{Sahar}} ==Overview== ==What are the Symptoms of cryopyrin-associated periodic syndrome?== ==What Cause...")
 
Line 5: Line 5:
  
 
==Overview==
 
==Overview==
 
+
The cryopyrin-associated periodic syndrome consists of three separate diseases that occur due to a defect in the same gene.
 
==What are the Symptoms of cryopyrin-associated periodic syndrome?==
 
==What are the Symptoms of cryopyrin-associated periodic syndrome?==
 
+
*The symptoms depend on the severity and type of the disease.
 +
*Generally, disease severity increases from mild to severe in the following order: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome, neonatal-onset multisystem inflammatory disease (NOMID).
 +
*
 
==What Causes cryopyrin-associated periodic syndrome?==
 
==What Causes cryopyrin-associated periodic syndrome?==
 
+
*CAPS occurs due to a defect in a gene that is responsible for the production of cryopyrin.
 +
*Cryopyrin is a protein which plays an important role in controlling inflammation.
 
==Who is at Highest Risk?==
 
==Who is at Highest Risk?==
  
Line 17: Line 20:
  
 
==Treatment Options==
 
==Treatment Options==
 
+
*Treatment options include:
 +
**Biologic agents that target interleukin-1 (IL-1)
 +
*Treatment for joint deformities:
 +
**Physical therapy
 +
**Splints
 +
**surgery (less common)
 +
*Symptomatic treatment:
 +
**Nonsteroidal anti-inflammatory drugs
 +
**Corticosteroids
 +
**Methotrexate
 
==Where to find Medical Care for cryopyrin-associated periodic syndrome?==
 
==Where to find Medical Care for cryopyrin-associated periodic syndrome?==
Medical care for (disease name) can be found [https://www.google.com/maps/search/hospitals/ here].
+
Medical care for cryopyrin-associated periodic syndrome can be found [https://www.google.com/maps/search/hospitals/ here].
 
 
 
==Prevention==
 
==Prevention==
 
+
*There is no preventive method for the cryopyrin-associated periodic syndrome.
 
==What to Expect (Outlook/Prognosis)?==
 
==What to Expect (Outlook/Prognosis)?==
  
 
==Possible Complications==
 
==Possible Complications==
 
+
*Renal failure
 +
*Hearing loss
 +
*Developmental delay (in NOMID)
 
==Sources==
 
==Sources==
 
http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm
 
http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm

Revision as of 18:36, 12 July 2019

{Cryopyrin-associated periodic syndrome}

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

The cryopyrin-associated periodic syndrome consists of three separate diseases that occur due to a defect in the same gene.

What are the Symptoms of cryopyrin-associated periodic syndrome?

  • The symptoms depend on the severity and type of the disease.
  • Generally, disease severity increases from mild to severe in the following order: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome, neonatal-onset multisystem inflammatory disease (NOMID).

What Causes cryopyrin-associated periodic syndrome?

  • CAPS occurs due to a defect in a gene that is responsible for the production of cryopyrin.
  • Cryopyrin is a protein which plays an important role in controlling inflammation.

Who is at Highest Risk?

Diagnosis

When to Seek Urgent Medical Care?

Treatment Options

  • Treatment options include:
    • Biologic agents that target interleukin-1 (IL-1)
  • Treatment for joint deformities:
    • Physical therapy
    • Splints
    • surgery (less common)
  • Symptomatic treatment:
    • Nonsteroidal anti-inflammatory drugs
    • Corticosteroids
    • Methotrexate

Where to find Medical Care for cryopyrin-associated periodic syndrome?

Medical care for cryopyrin-associated periodic syndrome can be found here.

Prevention

  • There is no preventive method for the cryopyrin-associated periodic syndrome.

What to Expect (Outlook/Prognosis)?

Possible Complications

  • Renal failure
  • Hearing loss
  • Developmental delay (in NOMID)

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm



Linked-in.jpg