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==Overview==
==Overview==
'''Coronary catheterization''' is an invasive procedure to access the [[coronary circulation]] and blood filled chambers of the [[heart]] using a [[catheter]]. It is performed for both diagnostic and interventional (treatment) purposes. Coronary catheterization is one of the several [[cardiology diagnostic tests and procedures]]. Specifically, coronary catheterization is a visually interpreted test performed to recognize occlusion, [[stenosis]], [[restenosis]], [[thrombosis]] or [[aneurysm|aneurysmal]] enlargement the [[coronary artery]] [[lumen]]s, [[heart chamber]] size, [[heart muscle]] contraction performance and some aspects of [[heart valve]] function. Important internal [[heart]] and [[lung]] [[blood pressure]]s, not measurable from outside the body, can be accurately measured during the test. The relevant problems that the test deals with most commonly occur as a result of advanced [[atherosclerosis]], [[atheroma]]activity within the wall of the coronary [[artery|arteries]]. Less frequently, other issues, [[heart valve|valvular]], [[heart muscle]] or [[arrhythmia]] issues are the primary focus of the test.<ref>Connolly JE. The development of coronary artery surgery: personal recollections. ''Tex Heart Inst J'' 2002;29:10-4. PMID 11995842.</ref> <ref>Proudfit WL, Shirey EK, Sones FM Jr. Selective cine coronary arteriography. Correlation with clinical findings in 1,000 patients. ''Circulation'' 1966;33:901-10. PMID 5942973.</ref> <ref>Sones FM, Shirey EK. Cine coronary arteriography. ''Mod Concepts Cardiovasc Dis'' 1962;31:735-8. PMID 13915182.</ref> <ref>Smith SC Jr, Feldman TE, Hirshfeld JW Jr, Jacobs AK, Kern MJ, King SB 3rd, Morrison DA, O'neill WW, Schaff HV, Whitlow PL, Williams DO, Antman EM, Smith SC Jr, Adams CD, Anderson JL, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK, Nishimura R, Ornato JP, Page RL, Riegel B; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention. ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention-Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). J Am Coll Cardiol. 2006 Jan 3;47(1):216-35. PMID 16386696</ref>
[[Cardiac catheterization]] refers to the insertion of hollow tubes (catheters) into various structures of the heart. When catheters are inserted specifically into the [[coronary arteries]] that supply blood to the [[heart muscle]] (the [[myocardium]]), this instrumentation is called [[coronary catheterization]]. [[Coronary catheterization]] is to be distinguished form [[left heart catheterization]] in which catheters (hollow tubes) are inserted into the blood filled chambers of the [[heart]].  


[[Coronary artery]] [[lumen|luminal]] [[stenosis|narrowing]] reduces the flow reserve for oxygenated blood to the heart, typically producing intermittent [[Angina pectoris|angina]] if very advanced; [[lumen|luminal]] occlusion usually produces a [[myocardial infarction|heart attack]]. However, it has been increasingly recognized, since the late 1980s, that coronary catheterization does not allow the recognition of the presence or absence of coronary [[atherosclerosis]] itself, only significant [[lumen|luminal]] changes which have occurred as a result of end stage complications of the [[atherosclerosis|atherosclerotic]] process. See [[IVUS]] and [[atheroma]] for a better understanding of this issue.
Once the catheter is inserted into the coronary artery, coronary angiography is the process of injecting iodinated contrast material (i.e. dye) into the [[coronary arteries]] to assess the [[coronary circulation]].  Coronary angiography is performed for both diagnostic and interventional (treatment) purposes.  Coronary angiography is a visually interpreted test performed to recognize occlusion or narrowing (referred to as a [[stenosis]]), [[restenosis]] (reblockage after successful opening of the artery), [[thrombosis]] (clot) or [[aneurysm|aneurysmal]] enlargement the [[coronary artery]] [[lumen]].  <ref>Proudfit WL, Shirey EK, Sones FM Jr. Selective cine coronary arteriography. Correlation with clinical findings in 1,000 patients. ''Circulation'' 1966;33:901-10. PMID 5942973.</ref> <ref>Sones FM, Shirey EK. Cine coronary arteriography. ''Mod Concepts Cardiovasc Dis'' 1962;31:735-8. PMID 13915182.</ref> <ref>Smith SC Jr, Feldman TE, Hirshfeld JW Jr, Jacobs AK, Kern MJ, King SB 3rd, Morrison DA, O'neill WW, Schaff HV, Whitlow PL, Williams DO, Antman EM, Smith SC Jr, Adams CD, Anderson JL, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK, Nishimura R, Ornato JP, Page RL, Riegel B; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention. ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention-Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). J Am Coll Cardiol. 2006 Jan 3;47(1):216-35. PMID 16386696</ref>
 
During coronary catheterization (often referred to as a '''cath''' by physicians), [[blood pressure]]s are recorded and [[X-Ray]] motion picture shadow-grams of the blood inside the [[coronary arteries]] are recorded.  In order to create the [[X-ray]] pictures, a [[physician]] guides a small tube-like device called a [[catheter]], typically ~2.0 mm (6-French) in diameter, through the large arteries of the body until the tip is just within the opening of one of the [[coronary arteries]].  By design, the [[catheter]] is smaller than the [[lumen]] of the [[artery]] it is placed in; internal/intraarterial blood pressures are monitored through the [[catheter]] to verify that the [[catheter]] does not block blood flow.
 
The [[catheter]] is itself designed to be radiodense for visibility and it allows a clear, watery, blood compatible [[radiocontrast]] agent, commonly called an [[X-ray]] dye, to be selectively injected and mixed with the blood flowing within the artery.  Typically 3-8 cc of the [[radiocontrast]] agent is injected for each image to make the [[blood flow]] visible for about 3-5 seconds as the [[radiocontrast]] agent is rapidly washed away into the [[coronary]] [[capillaries]] and then [[coronary]] [[vein]]s.  Without the [[X-ray]] dye injection, the blood and surrounding heart [[biological tissue|tissues]] appear, on [[X-ray]], as only a mildly-shape-changing, otherwise uniform water density mass; no details of the blood and internal organ structure are discernible.  The [[radiocontrast]] within the blood allows visualization of the blood flow within the arteries or heart chambers, depending on where it is injected.
 
If [[atheroma]], or [[clot]]s, are protruding into the [[lumen]], producing [[stenosis|narrowing]], the [[stenosis|narrowing]] is seen as either a [[stenosis|narrowing]] or increased haziness within the [[X-ray]] shadow images of the blood/dye column within that portion of the artery; this is as compared to adjacent, presumed healthier, less [[stenosis|stenotic]] areas.
 
For guidance regarding catheter positions during the examination, the physician mostly relies on detailed knowledge of internal anatomy, guide wire and catheter behavior and intermittently, briefly uses fluoroscopy and a low [[X-Ray]] dose to visualize when needed.  This is done without saving recordings of these brief looks.  When the physician is ready to record diagnostic views, which are saved and can be more carefully scrutinized later, he activates the equipment to apply a significantly higher [[X-Ray]] dose, termed cine, in order to create better quality motion picture images, having sharper [[radiodensity]] contrast, typically at 30 frames per second. The physician controls both the contrast injection, [[fluoroscopy]] and cine application timing so as to minimize the total amount of [[radiocontrast]] injected and times the [[X-Ray]] to the injection so as to minimize the total amount of [[X-Ray]] used. Doses of [[radiocontrast]] agents and [[X-Ray]] exposure times are routinely recorded in an effort to maximize safety.
 
The [[patient]] being examined or treated is usually awake during coronary catheterization, ideally with only [[local anaesthesia]] such as [[lidocaine]] and minimal general [[sedation]], throughout the procedure. Performing the procedure with the patient awake is safer as the [[patient]] can immediately report any discomfort or problems and thereby facilitate rapid correction of any undesirable events.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{Coronary angiography}}


[[Category:Angiopedia]]
[[Category:Angiopedia]]
[[Category:Cardiology]]
[[Category:Cardiology]]

Latest revision as of 19:34, 17 April 2015



Resident
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Coronary Angiography

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cardiac catheterization refers to the insertion of hollow tubes (catheters) into various structures of the heart. When catheters are inserted specifically into the coronary arteries that supply blood to the heart muscle (the myocardium), this instrumentation is called coronary catheterization. Coronary catheterization is to be distinguished form left heart catheterization in which catheters (hollow tubes) are inserted into the blood filled chambers of the heart.

Once the catheter is inserted into the coronary artery, coronary angiography is the process of injecting iodinated contrast material (i.e. dye) into the coronary arteries to assess the coronary circulation. Coronary angiography is performed for both diagnostic and interventional (treatment) purposes. Coronary angiography is a visually interpreted test performed to recognize occlusion or narrowing (referred to as a stenosis), restenosis (reblockage after successful opening of the artery), thrombosis (clot) or aneurysmal enlargement the coronary artery lumen. [1] [2] [3]

During coronary catheterization (often referred to as a cath by physicians), blood pressures are recorded and X-Ray motion picture shadow-grams of the blood inside the coronary arteries are recorded. In order to create the X-ray pictures, a physician guides a small tube-like device called a catheter, typically ~2.0 mm (6-French) in diameter, through the large arteries of the body until the tip is just within the opening of one of the coronary arteries. By design, the catheter is smaller than the lumen of the artery it is placed in; internal/intraarterial blood pressures are monitored through the catheter to verify that the catheter does not block blood flow.

The catheter is itself designed to be radiodense for visibility and it allows a clear, watery, blood compatible radiocontrast agent, commonly called an X-ray dye, to be selectively injected and mixed with the blood flowing within the artery. Typically 3-8 cc of the radiocontrast agent is injected for each image to make the blood flow visible for about 3-5 seconds as the radiocontrast agent is rapidly washed away into the coronary capillaries and then coronary veins. Without the X-ray dye injection, the blood and surrounding heart tissues appear, on X-ray, as only a mildly-shape-changing, otherwise uniform water density mass; no details of the blood and internal organ structure are discernible. The radiocontrast within the blood allows visualization of the blood flow within the arteries or heart chambers, depending on where it is injected.

If atheroma, or clots, are protruding into the lumen, producing narrowing, the narrowing is seen as either a narrowing or increased haziness within the X-ray shadow images of the blood/dye column within that portion of the artery; this is as compared to adjacent, presumed healthier, less stenotic areas.

For guidance regarding catheter positions during the examination, the physician mostly relies on detailed knowledge of internal anatomy, guide wire and catheter behavior and intermittently, briefly uses fluoroscopy and a low X-Ray dose to visualize when needed. This is done without saving recordings of these brief looks. When the physician is ready to record diagnostic views, which are saved and can be more carefully scrutinized later, he activates the equipment to apply a significantly higher X-Ray dose, termed cine, in order to create better quality motion picture images, having sharper radiodensity contrast, typically at 30 frames per second. The physician controls both the contrast injection, fluoroscopy and cine application timing so as to minimize the total amount of radiocontrast injected and times the X-Ray to the injection so as to minimize the total amount of X-Ray used. Doses of radiocontrast agents and X-Ray exposure times are routinely recorded in an effort to maximize safety.

The patient being examined or treated is usually awake during coronary catheterization, ideally with only local anaesthesia such as lidocaine and minimal general sedation, throughout the procedure. Performing the procedure with the patient awake is safer as the patient can immediately report any discomfort or problems and thereby facilitate rapid correction of any undesirable events.

References

  1. Proudfit WL, Shirey EK, Sones FM Jr. Selective cine coronary arteriography. Correlation with clinical findings in 1,000 patients. Circulation 1966;33:901-10. PMID 5942973.
  2. Sones FM, Shirey EK. Cine coronary arteriography. Mod Concepts Cardiovasc Dis 1962;31:735-8. PMID 13915182.
  3. Smith SC Jr, Feldman TE, Hirshfeld JW Jr, Jacobs AK, Kern MJ, King SB 3rd, Morrison DA, O'neill WW, Schaff HV, Whitlow PL, Williams DO, Antman EM, Smith SC Jr, Adams CD, Anderson JL, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK, Nishimura R, Ornato JP, Page RL, Riegel B; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention. ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention-Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). J Am Coll Cardiol. 2006 Jan 3;47(1):216-35. PMID 16386696