Contraction alkalosis

Revision as of 15:33, 9 October 2022 by 44.197.72.169 (talk)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

WikiDoc Resources for Contraction alkalosis

Articles

Most recent articles on Contraction alkalosis

Most cited articles on Contraction alkalosis

Review articles on Contraction alkalosis

Articles on Contraction alkalosis in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Contraction alkalosis

Images of Contraction alkalosis

Photos of Contraction alkalosis

Podcasts & MP3s on Contraction alkalosis

Videos on Contraction alkalosis

Evidence Based Medicine

Cochrane Collaboration on Contraction alkalosis

Bandolier on Contraction alkalosis

TRIP on Contraction alkalosis

Clinical Trials

Ongoing Trials on Contraction alkalosis at Clinical Trials.gov

Trial results on Contraction alkalosis

Clinical Trials on Contraction alkalosis at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Contraction alkalosis

NICE Guidance on Contraction alkalosis

NHS PRODIGY Guidance

FDA on Contraction alkalosis

CDC on Contraction alkalosis

Books

Books on Contraction alkalosis

News

Contraction alkalosis in the news

Be alerted to news on Contraction alkalosis

News trends on Contraction alkalosis

Commentary

Blogs on Contraction alkalosis

Definitions

Definitions of Contraction alkalosis

Patient Resources / Community

Patient resources on Contraction alkalosis

Discussion groups on Contraction alkalosis

Patient Handouts on Contraction alkalosis

Directions to Hospitals Treating Contraction alkalosis

Risk calculators and risk factors for Contraction alkalosis

Healthcare Provider Resources

Symptoms of Contraction alkalosis

Causes & Risk Factors for Contraction alkalosis

Diagnostic studies for Contraction alkalosis

Treatment of Contraction alkalosis

Continuing Medical Education (CME)

CME Programs on Contraction alkalosis

International

Contraction alkalosis en Espanol

Contraction alkalosis en Francais

Business

Contraction alkalosis in the Marketplace

Patents on Contraction alkalosis

Experimental / Informatics

List of terms related to Contraction alkalosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Contraction alkalosis refers to the increase in blood pH that occurs as a result of fluid losses. The change in pH is especially pronounced with acidic fluid losses caused by problems like vomiting.

Pathophysiology

Extracellular fluid (ECF) volume contraction is associated with decreased blood volume and decreased renal perfusion pressure. Three compensation mechanisms engage as a result:

  1. Renin secretion is increased
  2. Production of angiotensin II is increased
  3. Secretion of aldosterone is increased

Increases in angiotensin II causes increased Na+-K+ exchange and increased HCO3- (bicarbonate) reabsorption in the proximal tubule. Increased aldosterone secretion causes increased collecting duct - alpha intercalated cell H+ secretion, worsening the metabolic alkalosis. Additionally, increased aldosterone secretion causes increased distal tubule K+ secretion, causing the hypokalemia seen with contraction alkalosis.

Treatment

Treatment consists of NaCl infusion to correct ECF volume contraction and administration of K+ to replace urinary losses.

References

Template:WikiDoc Sources