Constrictive pericarditis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pericardial constriction has been associated with, protein losing enteropathy, nephrotic syndrome, and LFT abnormalities consistent with hepatic congestion and chylous ascites.


Laboratory findings

  • Complete blood count (CBC)
    • Dilutional anemia if congestive heart failure (CHF) is present
  • Leukocytosis
    • Infectious, bacteriologic, or rheumatologic etiology source or steroid therapy
  • Leukopenia
    • Malignancy and chemotherapeutic agents use
  • hyponatremia or pseudohyponatremia
  • Contraction alkalosis (hypochloremia with hypercarbia)
  • elevation of blood urea nitrogen (BUN) levels f
  • serum creatinine levels are observed
  • arterial blood gas measurement,
  • metabolic acidosis (ie, low pH and low bicarbonate),
  • with or without compensatory respiratory alkalosis (ie, decreased partial pressure of carbon dioxide
  • elevated transaminase levels
  • Hypoalbuminemia ( a protein-losing enteropathy (PLE)
  • proteinuria (nephrotic range)
  • elevated sedimentation rate (ESR), C-reactive protein (CRP) level (postpericardiotomy syndrome)
  • normocytic normochromic anemia
  • brain natriuretic peptide (BNP), mildly increased (<150 ng/L).
  • antinuclear antibody (ANA) or rheumatoid factor (RF)

References